日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CardioGenAI: a machine learning-based framework for re-engineering drugs for reduced hERG liability

CardioGenAI:一种基于机器学习的药物重设计框架,用于降低hERG易感性

Kyro, Gregory W; Martin, Matthew T; Watt, Eric D; Batista, Victor S

A Hybrid Transformer Architecture with a Quantized Self-Attention Mechanism Applied to Molecular Generation

一种应用于分子生成的具有量化自注意力机制的混合Transformer架构

Smaldone, Anthony M; Shee, Yu; Kyro, Gregory W; Farag, Marwa H; Chandani, Zohim; Kyoseva, Elica; Batista, Victor S

The Báa nnilah Program: Results of a Chronic-Illness Self-Management Cluster Randomized Trial with the Apsáalooke Nation

Báa nnilah 项目:与 Apsáalooke 民族合作开展的慢性病自我管理集群随机试验结果

Held, Suzanne; Feng, Du; McCormick, Alma; Schure, Mark; Other Medicine, Lucille; Hallett, John; Inouye, Jillian; Allen, Sarah; Holder, Shannon; Bull Shows, Brianna; Trottier, Coleen; Kyro, Alexi; Kropp, Samantha; Turns Plenty, Nicole

Turning up the heat mimics allosteric signaling in imidazole-glycerol phosphate synthase

提高温度可以模拟咪唑-甘油磷酸合成酶中的变构信号传导。

Maschietto, Federica; Morzan, Uriel N; Tofoleanu, Florentina; Gheeraert, Aria; Chaudhuri, Apala; Kyro, Gregory W; Nekrasov, Peter; Brooks, Bernard; Loria, J Patrick; Rivalta, Ivan; Batista, Victor S

Author Correction: Turning up the heat mimics allosteric signaling in imidazole-glycerol phosphate synthase

作者更正:提高温度可模拟咪唑-甘油磷酸合成酶中的变构信号传导

Maschietto, Federica; Morzan, Uriel N; Tofoleanu, Florentina; Gheeraert, Aria; Chaudhuri, Apala; Kyro, Gregory W; Nekrasov, Peter; Brooks, Bernard; Loria, J Patrick; Rivalta, Ivan; Batista, Victor S

Mapping N- to C-terminal allosteric coupling through disruption of a putative CD74 activation site in D-dopachrome tautomerase

通过破坏 D-多巴色素互变异构酶中假定的 CD74 激活位点来映射 N 端到 C 端的变构偶联

Emily Chen, Vinnie Widjaja, Gregory Kyro, Brandon Allen, Pragnya Das, Varsha M Prahaladan, Vineet Bhandari, Elias J Lolis, Victor S Batista, George P Lisi

MDiGest: A Python package for describing allostery from molecular dynamics simulations

MDiGest:一个用于描述分子动力学模拟中变构效应的Python软件包

Maschietto, Federica; Allen, Brandon; Kyro, Gregory W; Batista, Victor S

Parenteral Exposure of Mice to Ricin Toxin Induces Fatal Hypoglycemia by Cytokine-Mediated Suppression of Hepatic Glucose-6-Phosphatase Expression

小鼠经肠外途径暴露于蓖麻毒素可诱导致命性低血糖,其机制是通过细胞因子介导的肝脏葡萄糖-6-磷酸酶表达抑制。

Pincus, Seth H; Kyro, Alexi; Maresh, Grace A; Peters, Tami; Kempa, Jacob; Marcotte, Tamera K; Gao, Zhanguo; Ye, Jianping; Copié, Valérie; Song, Kejing

Structural Basis for Reduced Dynamics of Three Engineered HNH Endonuclease Lys-to-Ala Mutants for the Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-Associated 9 (CRISPR/Cas9) Enzyme

成簇的规律间隔短回文重复序列 (CRISPR) 相关 9 (CRISPR/Cas9) 酶的三种工程化 HNH 内切酶 Lys-to-Ala 突变体动力学降低的结构基础

Jimin Wang, Erin Skeens, Pablo R Arantes, Federica Maschietto, Brandon Allen, Gregory W Kyro, George P Lisi, Giulia Palermo, Victor S Batista

Generalizability of a Diabetes-Associated Country-Specific Exploratory Dietary Pattern Is Feasible Across European Populations

针对特定国家/地区开发的糖尿病相关探索性饮食模式,其适用性可推广至整个欧洲人群。

Jannasch, Franziska; Kröger, Janine; Agnoli, Claudia; Barricarte, Aurelio; Boeing, Heiner; Cayssials, Valerie; Colorado-Yohar, Sandra; Dahm, Christina C; Dow, Courtney; Fagherazzi, Guy; Franks, Paul W; Freisling, Heinz; Gunter, Marc J; Kerrison, Nicola D; Key, Timothy J; Khaw, Kay-Tee; Kühn, Tilman; Kyro, Cecilie; Mancini, Francesca Romana; Mokoroa, Olatz; Nilsson, Peter; Overvad, Kim; Palli, Domenico; Panico, Salvatore; García, Jose Ramón Quirós; Rolandsson, Olov; Sacerdote, Carlotta; Sánchez, Mariá-José; Sahrai, Mohammad Sediq; Schübel, Ruth; Sluijs, Ivonne; Spijkerman, Annemieke M W; Tjonneland, Anne; Tong, Tammy Y N; Tumino, Rosario; Riboli, Elio; Langenberg, Claudia; Sharp, Stephen J; Forouhi, Nita G; Schulze, Matthias B; Wareham, Nicholas J