PHGDH preserves one-carbon cycle to confer metabolic plasticity in chemoresistant gastric cancer during nutrient stress
在营养胁迫下,PHGDH 维持一碳循环,从而赋予化疗耐药性胃癌细胞代谢可塑性。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2217826120
Yoon, Bo Kyung; Kim, Hyeonhui; Oh, Tae Gyu; Oh, Se Kyu; Jo, Sugyeong; Kim, Minki; Chun, Kyu-Hye; Hwang, Nahee; Lee, Suji; Jin, Suyon; Atkins, Annette R; Yu, Ruth T; Downes, Michael; Kim, Jae-Woo; Kim, Hyunkyung; Evans, Ronald M; Cheong, Jae-Ho; Fang, Sungsoon