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Unique adipose tissue invariant natural killer T cell subpopulations control adipocyte turnover in mice

小鼠体内独特的脂肪组织不变自然杀伤T细胞亚群控制着脂肪细胞的更新。

Sang Mun Han # ，Eun Seo Park # ，Jeu Park # ，Hahn Nahmgoong ，Yoon Ha Choi ，Jiyoung Oh ，Kyung Min Yim ，Won Taek Lee ，Yun Kyung Lee ，Yong Geun Jeon ，Kyung Cheul Shin ，Jin Young Huh ，Sung Hee Choi ，Jiyoung Park ，Jong Kyoung Kim ，Jae Bum Kim

T细胞

A Novel Metabolic Detour for Pancreatic Cancer Survival

胰腺癌生存的新型代谢途径

期刊:Molecules and Cells

影响因子:6.5

doi:10.14348/molcells.2023.0067

Adipocyte HIF2α functions as a thermostat via PKA Cα regulation in beige adipocytes

脂肪细胞 HIF2α 通过 PKA Cα 调节在米色脂肪细胞中发挥恒温器的作用

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-022-30925-0

Ji Seul Han, Yong Geun Jeon, Minsik Oh, Gung Lee, Hahn Nahmgoong, Sang Mun Han, Jeehye Choi, Ye Young Kim, Kyung Cheul Shin, Jiwon Kim, Kyuri Jo, Sung Sik Choe, Eun Jung Park, Sun Kim, Jae Bum Kim

RNF20 Functions as a Transcriptional Coactivator for PPARγ by Promoting NCoR1 Degradation in Adipocytes

RNF20 通过促进脂肪细胞中的 NCoR1 降解，充当 PPARγ 的转录辅激活因子

期刊:Diabetes

影响因子:6.2

doi:10.2337/db19-0508

Yong Geun Jeon, Jae Ho Lee, Yul Ji, Jee Hyung Sohn, Dabin Lee, Dong Wook Kim, Seul Gi Yoon, Kyung Cheul Shin, Jeu Park, Je Kyung Seong, Je-Yoel Cho, Sung Sik Choe, Jae Bum Kim

Activation of invariant natural killer T cells stimulates adipose tissue remodeling via adipocyte death and birth in obesity

在肥胖症中，不变性自然杀伤T细胞的激活通过脂肪细胞的死亡和新生来刺激脂肪组织重塑。

期刊:Genes & Development

影响因子:7.7

doi:10.1101/gad.329557.119

Park, Jeu; Huh, Jin Young; Oh, Jiyoung; Kim, Jong In; Han, Sang Mun; Shin, Kyung Cheul; Jeon, Yong Geun; Choe, Sung Sik; Park, Jiyoung; Kim, Jae Bum

During Adipocyte Remodeling, Lipid Droplet Configurations Regulate Insulin Sensitivity through F-Actin and G-Actin Reorganization

在脂肪细胞重塑过程中，脂滴结构通过 F-肌动蛋白和 G-肌动蛋白重组调节胰岛素敏感性

期刊:Molecular and Cellular Biology

影响因子:3.2

doi:10.1128/MCB.00210-19

Jong In Kim, Jeu Park, Yul Ji, Kyuri Jo, Sang Mun Han, Jee Hyung Sohn, Kyung Cheul Shin, Ji Seul Han, Yong Geun Jeon, Hahn Nahmgoong, Kyung Hee Han, Jiwon Kim, Sun Kim, Sung Sik Choe, Jae Bum Kim

GABA-stimulated adipose-derived stem cells suppress subcutaneous adipose inflammation in obesity

GABA 刺激的脂肪干细胞可抑制肥胖患者的皮下脂肪炎症

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.1822067116

Injae Hwang, Kyuri Jo, Kyung Cheul Shin, Jong In Kim, Yul Ji, Yoon Jeong Park, Jeu Park, Yong Geun Jeon, Sojeong Ka, Sujin Suk, Hye Lim Noh, Sung Sik Choe, Assim A Alfadda, Jason K Kim, Sun Kim, Jae Bum Kim

Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation

巨噬细胞 VLDLR 介导肥胖引起的胰岛素抵抗和脂肪组织炎症

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-017-01232-w

Kyung Cheul Shin, Injae Hwang, Sung Sik Choe, Jeu Park, Yul Ji, Jong In Kim, Gha Young Lee, Sung Hee Choi, Jianhong Ching, Jean-Paul Kovalik, Jae Bum Kim

Immunology/Inflammation

Insulin Receptor

发表日期：2017

文献求助收藏

Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance

肥胖诱导的脂联素基因DNA高甲基化介导胰岛素抵抗

期刊:Nature Communications

影响因子:14.7

doi:10.1038/ncomms8585

A Young Kim ,Yoon Jeong Park ,Xuebo Pan ,Kyung Cheul Shin ,Soo-Heon Kwak ,Abdulelah F Bassas ,Reem M Sallam ,Kyong Soo Park ,Assim A Alfadda ,Aimin Xu ,Jae Bum Kim

PKA regulates autophagy through lipolysis during fasting

PKA 在禁食期间通过脂肪分解来调节自噬

Unique adipose tissue invariant natural killer T cell subpopulations control adipocyte turnover in mice

小鼠体内独特的脂肪组织不变自然杀伤T细胞亚群控制着脂肪细胞的更新。

A Novel Metabolic Detour for Pancreatic Cancer Survival

胰腺癌生存的新型代谢途径

Adipocyte HIF2α functions as a thermostat via PKA Cα regulation in beige adipocytes

脂肪细胞 HIF2α 通过 PKA Cα 调节在米色脂肪细胞中发挥恒温器的作用

RNF20 Functions as a Transcriptional Coactivator for PPARγ by Promoting NCoR1 Degradation in Adipocytes

RNF20 通过促进脂肪细胞中的 NCoR1 降解，充当 PPARγ 的转录辅激活因子

Activation of invariant natural killer T cells stimulates adipose tissue remodeling via adipocyte death and birth in obesity

在肥胖症中，不变性自然杀伤T细胞的激活通过脂肪细胞的死亡和新生来刺激脂肪组织重塑。

During Adipocyte Remodeling, Lipid Droplet Configurations Regulate Insulin Sensitivity through F-Actin and G-Actin Reorganization

在脂肪细胞重塑过程中，脂滴结构通过 F-肌动蛋白和 G-肌动蛋白重组调节胰岛素敏感性

GABA-stimulated adipose-derived stem cells suppress subcutaneous adipose inflammation in obesity

GABA 刺激的脂肪干细胞可抑制肥胖患者的皮下脂肪炎症

Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation

巨噬细胞 VLDLR 介导肥胖引起的胰岛素抵抗和脂肪组织炎症

Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance

肥胖诱导的脂联素基因DNA高甲基化介导胰岛素抵抗