日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade

传统两性霉素 B 可在白血病母细胞中诱发免疫原性细胞死亡标志物,介导对吞噬细胞的免疫刺激作用,并与 PD-L1 阻断产生协同作用

G Kofla, C Radecke, M Frentsch, W Walther, S Stintzing, H Riess, L Bullinger, I-K Na

Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia

在NPM1突变型急性髓系白血病小鼠模型中,以白血病前期细胞为靶点进行治疗

Uckelmann, Hannah J; Kim, Stephanie M; Wong, Eric M; Hatton, Charles; Giovinazzo, Hugh; Gadrey, Jayant Y; Krivtsov, Andrei V; Rücker, Frank G; Döhner, Konstanze; McGeehan, Gerard M; Levine, Ross L; Bullinger, Lars; Vassiliou, George S; Armstrong, Scott A

Heterodimerization of AML1/ETO with CBFβ is required for leukemogenesis but not for myeloproliferation

AML1/ETO 与 CBFβ 的异二聚化是白血病形成所必需的,但不是骨髓增殖所必需的

V N Thiel, B D Giaimo, P Schwarz, K Soller, V Vas, M Bartkuhn, T J Blätte, K Döhner, L Bullinger, T Borggrefe, H Geiger, F Oswald

Epo-induced erythroid maturation is dependent on Plcγ1 signaling

Epo诱导的红系细胞成熟依赖于Plcγ1信号通路

T M Schnöder ,P Arreba-Tutusaus ,I Griehl ,L Bullinger ,M Buschbeck ,S W Lane ,K Döhner ,C Plass ,D B Lipka ,F H Heidel ,T Fischer

Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia

复发性突变(包括 NPM1c)可激活急性髓系白血病中的 BRD4 依赖性核心转录程序

M A Dawson, E J Gudgin, S J Horton, G Giotopoulos, E Meduri, S Robson, E Cannizzaro, H Osaki, M Wiese, S Putwain, C Y Fong, C Grove, J Craig, A Dittmann, D Lugo, P Jeffrey, G Drewes, K Lee, L Bullinger, R K Prinjha, T Kouzarides, G S Vassiliou, B J P Huntly

Cell of origin determines clinically relevant subtypes of MLL-rearranged AML

来源细胞决定 MLL 重排 AML 的临床相关亚型

A V Krivtsov, M E Figueroa, A U Sinha, M C Stubbs, Z Feng, P J M Valk, R Delwel, K Döhner, L Bullinger, A L Kung, A M Melnick, S A Armstrong

Expression of postsynaptic Ca2+-activated K+ (SK) channels at C-bouton synapses in mammalian lumbar -motoneurons

哺乳动物腰椎运动神经元 C 端突触处突触后 Ca2+ 激活 K+ (SK) 通道的表达

Adam S Deardorff, Shannon H Romer, Zhihui Deng, Katie L Bullinger, Paul Nardelli, Timothy C Cope, Robert E W Fyffe