日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Regional conformational flexibility couples substrate specificity and scissile phosphate diester selectivity in human flap endonuclease 1

区域构象灵活性与人类瓣膜内切酶 1 中的底物特异性和可裂解磷酸二酯选择性相结合

Ian A Bennet, L David Finger, Nicola J Baxter, Benjamin Ambrose, Andrea M Hounslow, Mark J Thompson, Jack C Exell, Nur Nazihah B Md Shahari, Timothy D Craggs, Jonathan P Waltho, Jane A Grasby

Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site

细胞活性 N-羟基脲 FEN1 抑制剂可阻断底物进入活性位点

Jack C Exell, Mark J Thompson, L David Finger, Steven J Shaw, Judit Debreczeni, Thomas A Ward, Claire McWhirter, Catrine L B Siöberg, Daniel Martinez Molina, W Mark Abbott, Clifford D Jones, J Willem M Nissink, Stephen T Durant, Jane A Grasby

The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome

DNA 修复内切酶 XPG 与 Werner 综合征中缺陷的 WRN 解旋酶直接发生功能性相互作用

Kelly S Trego, Sophia B Chernikova, Albert R Davalos, J Jefferson P Perry, L David Finger, Cliff Ng, Miaw-Sheue Tsai, Steven M Yannone, John A Tainer, Judith Campisi, Priscilla K Cooper