日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

AUM-302, a novel triple PIM/PI3K/mTOR inhibitor, synergizes with RAS inhibition and impedes the growth of pancreatic ductal adenocarcinoma spheroids and organoids

AUM-302 是一种新型的三重 PIM/PI3K/mTOR 抑制剂,可与 RAS 抑制剂协同作用,抑制胰腺导管腺癌球体和类器官的生长。

Wen, Emma; Vera, Catalina; Kesavan, Sahaana; Kouassi, Fatim; LaComb, Joseph F; Zand, Neecki; Tuveson, David A; Habowski, Amber N; Baines, Antonio T; Bialkowska, Agnieszka B

SBFI Inhibitors Reprogram Transcriptomic Landscape of Prostate Cancer Cells Leading to Cell Death

SBFI抑制剂重编程前列腺癌细胞的转录组图谱,最终导致细胞死亡

Rajput, Shubhra; LaComb, Joseph F; Gordon, Chris; Wang, Hehe; Sarder, Manisha; Kaczocha, Martin; Ojima, Iwao; Bialkowska, Agnieszka B

CNS resident macrophages exhibit region-specific states and immunogenic responses during Rbpj-deficient brain arteriovenous malformation

在Rbpj缺陷型脑动静脉畸形中,中枢神经系统驻留巨噬细胞表现出区域特异性状态和免疫原性反应。

Nakisli, Sera; Fanelli, Kayleigh; LaComb, Julia; Arnold, Lily J; Nielsen, Corinne M

TR-107, an Agonist of Caseinolytic Peptidase Proteolytic Subunit, Disrupts Mitochondrial Metabolism and Inhibits the Growth of Human Colorectal Cancer Cells

TR-107,一种酪蛋白水解肽酶蛋白水解亚基的激动剂,可破坏线粒体代谢并抑制人类结直肠癌细胞的生长。

Michael Giarrizzo ,Joseph F LaComb ,Hetvi R Patel ,Rohan G Reddy ,John D Haley ,Lee M Graves ,Edwin J Iwanowicz ,Agnieszka B Bialkowska

Insights into the Interaction Landscape of the EVH1 Domain of Mena

对 Mena EVH1 结构域相互作用格局的深入研究

LaComb, Lanette; Ghosh, Agnidipta; Bonanno, Jeffrey B; Nilson, Daniel J; Poppel, Alex J; Dada, Lucas; Cahill, Sean M; Maianti, Juan Pablo; Kitamura, Seiya; Cowburn, David; Almo, Steven C

The Role of Krüppel-like Factors in Pancreatic Physiology and Pathophysiology

Krüppel样因子在胰腺生理和病理生理中的作用

Giarrizzo, Michael; LaComb, Joseph F; Bialkowska, Agnieszka B

The Role of MicroRNAs in Pancreatitis Development and Progression

微小RNA在胰腺炎发生发展中的作用

Patel, Hetvi R; Diaz Almanzar, Vanessa M; LaComb, Joseph F; Ju, Jingfang; Bialkowska, Agnieszka B

AUM302, a novel triple kinase PIM/PI3K/mTOR inhibitor, is a potent in vitro pancreatic cancer growth inhibitor

AUM302 是一种新型三重激酶 PIM/PI3K/mTOR 抑制剂,是一种有效的体外胰腺癌生长抑制剂

Komala Ingle, Joseph F LaComb, Lee M Graves, Antonio T Baines, Agnieszka B Bialkowska

5-FU-miR-15a Inhibits Activation of Pancreatic Stellate Cells by Reducing YAP1 and BCL-2 Levels In Vitro

5-FU-miR-15a 通过降低体外 YAP1 和 BCL-2 水平抑制胰腺星状细胞的活化

Vanessa M Diaz Almanzar, Kunal Shah, Joseph F LaComb, Aisharja Mojumdar, Hetvi R Patel, Jacky Cheung, Meiyi Tang, Jingfang Ju, Agnieszka B Bialkowska

Intestinal Epithelial Regeneration in Response to Ionizing Irradiation

电离辐射诱导的肠上皮再生

Orzechowska-Licari, Emilia J; LaComb, Joseph F; Giarrizzo, Michael; Yang, Vincent W; Bialkowska, Agnieszka B