日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Liver lipid droplet cholesterol content is a key determinant of metabolic dysfunction-associated steatohepatitis

肝脏脂滴胆固醇含量是代谢功能障碍相关性脂肪性肝炎的关键决定因素。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2502978122
Sakuma, Ikki; Gaspar, Rafael C; Nasiri, Ali R; Dufour, Sylvie; Kahn, Mario; Zheng, Jie; LaMoia, Traci E; Guerra, Mateus T; Taki, Yuki; Kawashima, Yusuke; Yimlamai, Dean; Perelis, Mark; Vatner, Daniel F; Petersen, Kitt Falk; Huttasch, Maximilian; Knebel, Birgit; Kahl, Sabine; Roden, Michael; Samuel, Varman T; Tanaka, Tomoaki; Shulman, Gerald I
肝炎
代谢
发表日期：2025
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Liver lipid droplet cholesterol content is a key determinant of metabolic dysfunction-associated steatohepatitis

肝脏脂滴胆固醇含量是代谢功能障碍相关性脂肪性肝炎的关键决定因素。

期刊:
影响因子:
doi:10.1101/2025.02.25.640203
Sakuma, Ikki; Gaspar, Rafael C; Nasiri, Ali R; Dufour, Sylvie; Kahn, Mario; Zheng, Jie; LaMoia, Traci E; Guerra, Mateus T; Taki, Yuki; Kawashima, Yusuke; Yimlamai, Dean; Perelis, Mark; Vatner, Daniel F; Petersen, Kitt Falk; Huttasch, Maximilian; Knebel, Birgit; Kahl, Sabine; Roden, Michael; Samuel, Varman T; Tanaka, Tomoaki; Shulman, Gerald I
肝炎
代谢
发表日期：2025
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Cytosolic calcium regulates hepatic mitochondrial oxidation, intrahepatic lipolysis, and gluconeogenesis via CAMKII activation.

胞质钙通过 CAMKII 激活调节肝线粒体氧化、肝内脂肪分解和糖异生

期刊:Cell Metabolism
影响因子:30.9
doi:10.1016/j.cmet.2024.07.016
LaMoia Traci E, Hubbard Brandon T, Guerra Mateus T, Nasiri Ali, Sakuma Ikki, Kahn Mario, Zhang Dongyan, Goodman Russell P, Nathanson Michael H, Sancak Yasemin, Perelis Mark, Mootha Vamsi K, Shulman Gerald I
线粒体
发表日期：2024
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SGLT2 inhibition alters substrate utilization and mitochondrial redox in healthy and failing rat hearts

SGLT2抑制剂可改变健康和衰竭大鼠心脏的底物利用率和线粒体氧化还原状态

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI176708
Goedeke, Leigh; Ma, Yina; Gaspar, Rafael C; Nasiri, Ali; Lee, Jieun; Zhang, Dongyan; Galsgaard, Katrine Douglas; Hu, Xiaoyue; Zhang, Jiasheng; Guerrera, Nicole; Li, Xiruo; LaMoia, Traci; Hubbard, Brandon T; Haedersdal, Sofie; Wu, Xiaohong; Stack, John; Dufour, Sylvie; Butrico, Gina Marie; Kahn, Mario; Perry, Rachel J; Cline, Gary W; Young, Lawrence H; Shulman, Gerald I
SGLT2
线粒体
Rat
发表日期：2024
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Small molecule inhibition of glycogen synthase I reduces muscle glycogen content and improves biomarkers in a mouse model of Pompe disease.

小分子抑制糖原合成酶 I 可降低庞贝氏症小鼠模型的肌肉糖原含量并改善生物标志物

期刊:American Journal of Physiology-Endocrinology and Metabolism
影响因子:3.1
doi:10.1152/ajpendo.00175.2024
Gaspar Rafael Calais, Sakuma Ikki, Nasiri Ali, Hubbard Brandon T, LaMoia Traci E, Leitner Brooks P, Tep Samnang, Xi Yannan, Green Eric M, Ullman Julie C, Petersen Kitt Falk, Shulman Gerald I
信号转导
Mouse
发表日期：2024
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MAD2-Dependent Insulin Receptor Endocytosis Regulates Metabolic Homeostasis

MAD2 依赖性胰岛素受体内吞作用调节代谢稳态

期刊:Diabetes
影响因子:6.2
doi:10.2337/db23-0314
Junhee Park, Catherine Hall, Brandon Hubbard, Traci LaMoia, Rafael Gaspar, Ali Nasiri, Fang Li, Hanrui Zhang, Jiyeon Kim, Rebecca A Haeusler, Domenico Accili, Gerald I Shulman, Hongtao Yu, Eunhee Choi
代谢
Insulin Receptor
发表日期：2023
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Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis

二甲双胍、苯乙双胍和加利根抑制复合物IV活性，从而降低甘油衍生的糖异生作用。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2122287119
LaMoia, Traci E; Butrico, Gina M; Kalpage, Hasini A; Goedeke, Leigh; Hubbard, Brandon T; Vatner, Daniel F; Gaspar, Rafael C; Zhang, Xian-Man; Cline, Gary W; Nakahara, Keita; Woo, Seungwan; Shimada, Atsuhiro; Hüttemann, Maik; Shulman, Gerald I
发表日期：2022
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Cellular and Molecular Mechanisms of Metformin Action

二甲双胍作用的细胞和分子机制

期刊:Endocrine Reviews
影响因子:22
doi:10.1210/endrev/bnaa023
LaMoia, Traci E; Shulman, Gerald I
细胞生物学
发表日期：2021
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High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice

高剂量糖精补充剂不会引起健康人类和小鼠肠道菌群变化或葡萄糖不耐受

期刊:Microbiome
影响因子:13.8
doi:10.1186/s40168-020-00976-w
Joan Serrano, Kathleen R Smith, Audra L Crouch, Vandana Sharma, Fanchao Yi, Veronika Vargova, Traci E LaMoia, Lydia M Dupont, Vanida Serna, Fenfen Tang, Laisa Gomes-Dias, Joshua J Blakeslee, Emmanuel Hatzakis, Scott N Peterson, Matthew Anderson, Richard E Pratley, George A Kyriazis
微生物学
Human
发表日期：2021
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T1R2 receptor-mediated glucose sensing in the upper intestine potentiates glucose absorption through activation of local regulatory pathways

上肠中 T1R2 受体介导的葡萄糖感应通过激活局部调节通路增强葡萄糖吸收

期刊:Molecular Metabolism
影响因子:7
doi:10.1016/j.molmet.2018.08.009
Kathleen Smith, Elnaz Karimian Azari, Traci E LaMoia, Tania Hussain, Veronika Vargova, Katalin Karolyi, Paula P Veldhuis, Juan Pablo Arnoletti, Sebastian G de la Fuente, Richard E Pratley, Timothy F Osborne, George A Kyriazis
信号转导
WB
发表日期：2018
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