Laaker相关文献与解析，生知库 | 链接生命科学的每一步

Cribriform Plate Microenvironment Assembles a Suppressive Myeloid Network during EAE-induced Neuroinflammation.

筛板微环境在 EAE 诱导的神经炎症期间组装抑制性髓系网络。

doi:10.64898/2026.01.07.698165

Laaker Collin, Hsu Martin, Madrid Andy, Port Jenna, Vrba Sophia M, Herbath Melinda, Baenen Cameron, Kumar Mohan, Priyathilaka Thanthrige Thiunuwan, Sandor Matyas, Fabry Zsuzsanna

Perineural immune environment of olfactory nerves is reshaped by neuroinflammatory drainage and connects to ethmoid bone marrow

嗅神经周围的免疫环境因神经炎症引流而重塑，并与筛骨骨髓相连。

期刊:Science Advances

影响因子:11.7

doi:10.1126/sciadv.adt9591

Collin J Laaker ，Kristof G Kovacs ，Cameron M Baenen ，Martin Hsu ，Jenna M Port ，Sophia M Vrba ，Mohan Kumar ，Annika J Hubacek ，Melinda Herbath ，Thanthrige Thiunuwan Priyathilaka ，Matyas Sandor ，Zsuzsanna Fabry

Dual role of vascular endothelial growth factor-C in post-stroke recovery

血管内皮生长因子-C在卒中后恢复中的双重作用

期刊:Journal of Experimental Medicine

影响因子:10.6

doi:10.1084/jem.20231816

Choi, Yun Hwa; Hsu, Martin; Laaker, Collin; Port, Jenna; Kovács, Kristóf G; Herbath, Melinda; Yang, Heeyoon; Cismaru, Peter; Johnson, Alexis M; Spellman, Bailey; Wigand, Kelsey; Sandor, Matyas; Fabry, Zsuzsanna

心血管

发表日期：2025

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Early life cancer and chemotherapy lead to cognitive deficits related to alterations in microglial-associated gene expression in prefrontal cortex

早期癌症和化疗会导致认知缺陷，这与前额叶皮层中小胶质细胞相关基因表达的改变有关。

期刊:Brain Behavior and Immunity

影响因子:7.6

doi:10.1016/j.bbi.2023.07.009

Laaker, Collin J; Cantelon, Claire; Davis, Alyshia B; Lloyd, Kelsey R; Agyeman, Nana; Hiltz, Adam R; Smith, Brittany L; Konsman, Jan Pieter; Reyes, Teresa M

HAA by the first {Mn(iii)OH} complex with all O-donor ligands

第一个含所有氧供体配体的{Mn(iii)OH}配合物对HAA的作用

期刊:Chemical Science

影响因子:7.4

doi:10.1039/d3sc01971c

Moore, Shawn M; Sun, Chen; Steele, Jennifer L; Laaker, Ellen M; Rheingold, Arnold L; Doerrer, Linda H

发表日期：2023

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Immune cells as messengers from the CNS to the periphery: the role of the meningeal lymphatic system in immune cell migration from the CNS

免疫细胞作为从中枢神经系统到外周的信使：脑膜淋巴系统在免疫细胞从中枢神经系统迁移中的作用

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2023.1233908

Laaker, Collin; Baenen, Cameron; Kovács, Kristóf G; Sandor, Matyas; Fabry, Zsuzsanna

Dual role of Vascular Endothelial Growth Factor-C (VEGF-C) in post-stroke recovery

血管内皮生长因子-C (VEGF-C) 在卒中后恢复中的双重作用

期刊:

影响因子:

doi:10.1101/2023.08.30.555144

Yun Hwa Choi, Martin Hsu, Collin Laaker, Melinda Herbath, Heeyoon Yang, Peter Cismaru, Alexis M Johnson, Bailey Spellman, Kelsey Wigand, Matyas Sandor, Zsuzsanna Fabry

信号转导

发表日期：2023

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Neuroinflammation creates an immune regulatory niche at the meningeal lymphatic vasculature near the cribriform plate

神经炎症在筛板附近的脑膜淋巴管系统形成免疫调节微环境。

期刊:Nature Immunology

影响因子:27.7

doi:10.1038/s41590-022-01158-6

Martin Hsu ，Collin Laaker ，Andy Madrid ，Melinda Herbath ，Yun Hwa Choi ，Matyas Sandor ，Zsuzsanna Fabry

CXCL13 expressed on inflamed cerebral blood vessels recruit IL-21 producing TFH cells to damage neurons following stroke

发炎的脑血管上表达的 CXCL13 会募集产生 IL-21 的 TFH 细胞来破坏中风后的神经元

期刊:Journal of Neuroinflammation

影响因子:9.3

doi:10.1186/s12974-022-02490-2

Aditya Rayasam, Julie A Kijak, Lee Kissel, Yun Hwa Choi, Taehee Kim, Martin Hsu, Dinesh Joshi, Collin J Laaker, Peter Cismaru, Anders Lindstedt, Krisztian Kovacs, Raghu Vemuganti, Shing Yan Chiu, Thanthrige Thiunuwan Priyathilaka, Matyas Sandor, Zsuzsanna Fabry

VEGFR Blockade Reduces Mycobacterium tuberculosis-Induced Lung Pathology in Immunocompromised Mice.

VEGFR阻断可减轻免疫缺陷小鼠中结核分枝杆菌引起的肺部病变。

Cribriform Plate Microenvironment Assembles a Suppressive Myeloid Network during EAE-induced Neuroinflammation.

筛板微环境在 EAE 诱导的神经炎症期间组装抑制性髓系网络。

Perineural immune environment of olfactory nerves is reshaped by neuroinflammatory drainage and connects to ethmoid bone marrow

嗅神经周围的免疫环境因神经炎症引流而重塑，并与筛骨骨髓相连。

Dual role of vascular endothelial growth factor-C in post-stroke recovery

血管内皮生长因子-C在卒中后恢复中的双重作用

Early life cancer and chemotherapy lead to cognitive deficits related to alterations in microglial-associated gene expression in prefrontal cortex

早期癌症和化疗会导致认知缺陷，这与前额叶皮层中小胶质细胞相关基因表达的改变有关。

HAA by the first {Mn(iii)OH} complex with all O-donor ligands

第一个含所有氧供体配体的{Mn(iii)OH}配合物对HAA的作用

Immune cells as messengers from the CNS to the periphery: the role of the meningeal lymphatic system in immune cell migration from the CNS

免疫细胞作为从中枢神经系统到外周的信使：脑膜淋巴系统在免疫细胞从中枢神经系统迁移中的作用

Dual role of Vascular Endothelial Growth Factor-C (VEGF-C) in post-stroke recovery

血管内皮生长因子-C (VEGF-C) 在卒中后恢复中的双重作用

Neuroinflammation creates an immune regulatory niche at the meningeal lymphatic vasculature near the cribriform plate

神经炎症在筛板附近的脑膜淋巴管系统形成免疫调节微环境。

CXCL13 expressed on inflamed cerebral blood vessels recruit IL-21 producing TFH cells to damage neurons following stroke

发炎的脑血管上表达的 CXCL13 会募集产生 IL-21 的 TFH 细胞来破坏中风后的神经元