日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Therapeutic targeting of chronic kidney disease-associated DAMPs differentially contributing to vascular pathology

针对慢性肾脏病相关损伤相关分子模式(DAMPs)的治疗靶向作用,这些DAMPs对血管病理学有不同的贡献

Mazzarino, Morgane; Cetin, Esra; Bartosova, Maria; Marinovic, Iva; Ipseiz, Natacha; Hughes, Timothy R; Schmitt, Claus Peter; Ramji, Dipak P; Labéta, Mario O; Raby, Anne-Catherine

Calprotectin blockade inhibits long-term vascular pathology following peritoneal dialysis-associated bacterial infection

钙卫蛋白阻断可抑制腹膜透析相关细菌感染后的长期血管病理

Esra Cetin #, Morgane Mazzarino #, Guadalupe T González-Mateo, Valeria Kopytina, Soma Meran, Donald Fraser, Manuel López-Cabrera, Mario O Labéta, Anne-Catherine Raby

Targeting Toll-like receptors with soluble Toll-like receptor 2 prevents peritoneal dialysis solution-induced fibrosis

以可溶性 Toll 样受体 2 为靶点可预防腹膜透析液诱发的纤维化

Anne-Catherine Raby, Guadalupe T González-Mateo, Aled Williams, Nicholas Topley, Donald Fraser, Manuel López-Cabrera, Mario O Labéta

Toll-Like Receptors 2 and 4 Are Potential Therapeutic Targets in Peritoneal Dialysis-Associated Fibrosis

Toll 样受体 2 和 4 是腹膜透析相关纤维化的潜在治疗靶点

Anne-Catherine Raby, Chantal S Colmont, Ann Kift-Morgan, Jörg Köhl, Matthias Eberl, Donald Fraser, Nicholas Topley, Mario O Labéta

Human peritoneal mesothelial cells respond to bacterial ligands through a specific subset of Toll-like receptors

人类腹膜间皮细胞通过特定的Toll样受体亚群对细菌配体做出反应。

Colmont, Chantal S; Raby, Anne-Catherine; Dioszeghy, Vincent; Lebouder, Emmanuel; Foster, Thomas L; Jones, Simon A; Labéta, Mario O; Fielding, Ceri A; Topley, Nicholas

TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2

TLR 激活通过负向调节第二个 C5a 受体 C5L2 来增强 C5a 诱导的促炎反应

Anne-Catherine Raby, Benjamin Holst, James Davies, Chantal Colmont, Yves Laumonnier, Barbara Coles, Sanjoy Shah, Judith Hall, Nicholas Topley, Jörg Köhl, B Paul Morgan, Mario O Labéta

Soluble TLR2 reduces inflammation without compromising bacterial clearance by disrupting TLR2 triggering

可溶性 TLR2 通过破坏 TLR2 触发机制来减轻炎症,同时又不影响细菌清除

Anne-Catherine Raby, Emmanuel Le Bouder, Chantal Colmont, James Davies, Peter Richards, Barbara Coles, Christopher H George, Simon A Jones, Paul Brennan, Nicholas Topley, Mario O Labéta

Innate recognition of bacteria in human milk is mediated by a milk-derived highly expressed pattern recognition receptor, soluble CD14

母乳中细菌的先天识别是由乳源性高表达模式识别受体可溶性 CD14 介导的

M O Labéta, K Vidal, J E Nores, M Arias, N Vita, B P Morgan, J C Guillemot, D Loyaux, P Ferrara, D Schmid, M Affolter, L K Borysiewicz, A Donnet-Hughes, E J Schiffrin