日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cryo-EM structure and regulation of human NAD kinase

人类 NAD 激酶的低温电子显微镜结构和调控

Prakash P Praharaj, Yang Li, Charline Mary, Mona H Soflaee, Kevin Ryu, Dohun Kim, Diem H Tran, Trishna Dey, Harrison J Tom, Halie Rion, Muriel Gelin, Andrew Lemoff, Lauren G Zacharias, João S Patricio, Thomas P Mathews, Zhe Chen, Corinne Lionne, Gerta Hoxhaj, Gilles Labesse

Fragment-based drug design of a bacterial kinase inhibitor capable of increasing the antibiotic sensitivity of clinical isolates

基于片段的细菌激酶抑制剂药物设计,可提高临床分离株对抗生素的敏感性

Kowalewski, Julien; Deutscher, Robin; Richardoz, Marion; Tomaszczyk, Mathilde; Gelin, Muriel; Labesse, Gilles; Hausch, Felix; Wright, Gerard D; Dunyach-Remy, Catherine; Guichou, Jean-François; Lionne, Corinne

APH Inhibitors that Reverse Aminoglycoside Resistance in Enterococcus casseliflavus

逆转卡氏肠球菌氨基糖苷类耐药性的APH抑制剂

Kaplan, Elise; Chaloin, Laurent; Guichou, Jean-François; Berrou, Kévin; Rahimova, Rahila; Labesse, Gilles; Lionne, Corinne

SLiMAn 2.0: meaningful navigation through peptide-protein interaction networks

SLiMAn 2.0:肽-蛋白质相互作用网络的有效导航

Reys, Victor; Pons, Jean-Luc; Labesse, Gilles

Increases in cyclin A/Cdk activity and in PP2A-B55 inhibition by FAM122A are key mitosis-inducing events

细胞周期蛋白 A/Cdk 活性的增加和 FAM122A 对 PP2A-B55 的抑制是关键的有丝分裂诱导事件

Benjamin Lacroix #, Suzanne Vigneron #, Jean Claude Labbé, Lionel Pintard, Corinne Lionne, Gilles Labesse, Anna Castro, Thierry Lorca

Structure-based design, synthesis and biological evaluation of a NAD+ analogue targeting Pseudomonas aeruginosa NAD kinase

针对铜绿假单胞菌 NAD 激酶的 NAD+ 类似物的结构设计、合成和生物学评价

Rahila Rahimova, Pauline Nogaret, Valérie Huteau, Muriel Gelin, David A Clément, Gilles Labesse, Sylvie Pochet, Anne-Béatrice Blanc-Potard, Corinne Lionne

Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases

通过工程化 IMP 脱氢酶深入了解 Bateman 结构域在分子和生理水平上的作用

Antoine Gedeon, Nour Ayoub, Sébastien Brûlé, Bertrand Raynal, Gouzel Karimova, Muriel Gelin, Ariel Mechaly, Ahmed Haouz, Gilles Labesse, Hélène Munier-Lehmann

Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation

人类 NADK2 的晶体结构揭示了赖氨酸乙酰化引起的二聚体组织和活性位点闭塞

Charline Mary, Mona Hoseini Soflaee, Rushendhiran Kesavan, Muriel Gelin, Harrison Brown, G Zacharias, Thomas P Mathews, Andrew Lemoff, Corinne Lionne, Gilles Labesse, Gerta Hoxhaj

Structural evolution of the ancient enzyme, dissimilatory sulfite reductase

古老酶——异化亚硫酸盐还原酶的结构演化

Colman, Daniel R; Labesse, Gilles; Swapna, Gurla V T; Stefanakis, Johanna; Montelione, Gaetano T; Boyd, Eric S; Royer, Catherine A

The study of the determinants controlling Arpp19 phosphatase-inhibitory activity reveals an Arpp19/PP2A-B55 feedback loop

控制arpp19磷酸酶抑制活性的决定因素的研究揭示了arpp19/pp2a-b55反馈回路

Jean Claude Labbé, Suzanne Vigneron, Francisca Méchali, Perle Robert, Sylvain Roque, Cindy Genoud, Perrine Goguet-Rubio, Phillipe Barthe, Gilles Labesse, Martin Cohen-Gonsaud, Anna Castro, Thierry Lorca