日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC-Derived Cortical Organoids.

自噬激活剂可使异常的 Tau 蛋白稳态正常化，并挽救人类家族性阿尔茨海默病 iPSC 衍生皮质类器官中的突触。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202514783
Labra Sergio R, Compher Jadon, Prabhavalkar Akhil, Almaraz Mireya, Cedeño Kwong Claudia, Baal Christine, Talantova Maria, Dolatabadi Nima, Piña-Sanz Julian, Wang Yubo, Yoon Leonard, Ghatak Swagata, Gao Zi, Zhang Yuting, Trudler Dorit, Massey Lynee, Lin Wei, Balistreri Anthony, Bula Michael, Schork Nicholas J, Mondala Tony S, Head Steven R, Kelly Jeffery W, Lipton Stuart A
阿尔茨海默症
Human
神经科学
TAU
Autophagy
自噬
发表日期：2026
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A strong start for sustained success: inclusivity through a national group mentorship program for first-year graduate students

良好的开端是持续成功的关键：通过面向一年级研究生的全国性团体导师计划实现包容性

期刊:
影响因子:
doi:10.64898/2026.03.12.710679
Labra, Sergio R; Tornini, Valerie A; Salazar, Maria Pia Rodriguez; Cossio, Daniela M; Gelpí, Rebekah A; Perez, Bryan E Rubio; Rodríguez, Yanitza M; Sandoval, Gerardo Leana; Hernandez, Kimberly; Goldman, Olivia V; Fernandez, Robert W
发表日期：2026
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Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids.

MEF2C自闭症患者hiPSC神经元和脑类器官中miRNA表达和兴奋失调

期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-024-02761-9
Trudler Dorit, Ghatak Swagata, Bula Michael, Parker James, Talantova Maria, Luevanos Melissa, Labra Sergio, Grabauskas Titas, Noveral Sarah Moore, Teranaka Mayu, Schahrer Emily, Dolatabadi Nima, Bakker Clare, Lopez Kevin, Sultan Abdullah, Patel Parth, Chan Agnes, Choi Yongwook, Kawaguchi Riki, Stankiewicz Pawel, Garcia-Bassets Ivan, Kozbial Piotr, Rosenfeld Michael G, Nakanishi Nobuki, Geschwind Daniel H, Chan Shing Fai, Lin Wei, Schork Nicholas J, Ambasudhan Rajesh, Lipton Stuart A
神经科学
3D/类器官
miRNA
发表日期：2025
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Detecting Boolean Asymmetric Relationships With a Loop Counting Technique and its Implications for Analyzing Heterogeneity Within Gene Expression Datasets

利用循环计数技术检测布尔不对称关系及其在分析基因表达数据集异质性中的应用

期刊:
影响因子:
doi:10.1109/TCBB.2024.3487434
Zhou, Haosheng; Lin, Wei; Labra, Sergio R; Lipton, Stuart A; Elman, Jeremy A; Schork, Nicholas J; Rangan, Aaditya V
发表日期：2025
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Autophagy activators normalize aberrant Tau proteostasis and rescue synapses in human familial Alzheimer's disease iPSC-derived cortical organoids.

自噬激活剂可使异常的 Tau 蛋白稳态正常化，并挽救人类家族性阿尔茨海默病 iPSC 衍生皮质类器官中的突触

期刊:
影响因子:
doi:10.1101/2025.06.25.661453
Labra Sergio R, Compher Jadon, Prabhavalkar Akhil, Almaraz Mireya, Kwong Claudia Cedeño, Baal Christine, Talantova Maria, Dolatabadi Nima, Piña-Sanz Julian, Wang Yubo, Yoon Leonard, Ghatak Swagata, Gao Zi, Zhang Yuting, Trudler Dorit, Massey Lynee, Lin Wei, Balistreri Anthony, Bula Michael, Schork Nicholas J, Mondala Tony S, Head Steven R, Kelly Jeffery W, Lipton Stuart A
信号转导
Autophagy
Human
3D/类器官
自噬
发表日期：2025
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Single‐cell spatial and non‐spatial RNA sequencing on herpes simplex virus 1 (HSV‐1) infected 2D and 3D cerebral organoids reveal molecular granularity on virus‐human gene interactions in Alzheimer’s disease

对单纯疱疹病毒1型（HSV-1）感染的二维和三维脑类器官进行单细胞空间和非空间RNA测序，揭示了阿尔茨海默病中病毒-人类基因相互作用的分子精细性

期刊:Alzheimers & Dementia
影响因子:11.1
doi:10.1101/2025.06.03.25328936
Barajas, Jonathan; Yang, Zhi; Agyare, Edward; Zhu, Xueyou; Yoon, Saun-Joo; Han, Bo; McClatchy, Daniel B; Labra, Sergio R; Baal, Christine; Lipton, Stuart A; Yates, John R III; Dawes, Pepper; Barton, Nathaniel J; Orszulak, Adrian R; Chigas, Samantha M; Tran, Khanh; Sundstrom, Jonathan; Olson, Meagan N; Murray, Liam F; Oh, HyungSuk; Church, George M; Knipe, David M; Readhead, Benjamin; Chan, Yingleong; Lim, Elaine T
炎症/感染
神经科学
细胞生物学
阿尔茨海默症
3D/类器官
微生物学
单细胞
疱疹
发表日期：2024
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Single-molecule fluorescence studies of intrinsically disordered proteins and liquid phase separation

单分子荧光研究固有无序蛋白和液相分离

期刊:Biochimica et Biophysica Acta-Proteins and Proteomics
影响因子:2.3
doi:10.1016/j.bbapap.2019.04.007
Nasir, Irem; Onuchic, Paulo L; Labra, Sergio R; Deniz, Ashok A
IF
相分离
发表日期：2019
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