Lacadena相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

GPA33-Targeted Trimeric Immunotoxin Exhibits Enhanced Antitumor Activity in Human Colorectal Cancer Xenografts

靶向GPA33的三聚体免疫毒素在人结直肠癌异种移植模型中表现出增强的抗肿瘤活性

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms27020764

Ruiz-de-la-Herrán, Javier; Narbona, Javier; Gordo, Rubén G; Sanz, Laura; Lacadena, Javier

免疫/内分泌

发表日期：2026

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An Innovative Immunotoxin Design Against Allergy Based on the IL-33 Cytokine and the Ribotoxin α-Sarcin

一种基于IL-33细胞因子和核糖毒素α-沙雷氏菌素的创新型抗过敏免疫毒素设计

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26199827

Narbona, Javier; Lázaro-Gorines, Rodrigo; Gutiérrez-Carmona, Adrián; López-Rodríguez, Juan Carlos; Villalba, Mayte; Lacadena, Javier

细胞生物学

免疫/内分泌

发表日期：2025

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Combination of T cell-redirecting strategies with a bispecific antibody blocking TGF-β and PD-L1 enhances antitumor responses

细胞重定向策略与阻断 TGF-β 和 PD-L1 的双特异性抗体相结合可增强抗肿瘤反应

期刊:Oncoimmunology

doi:10.1080/2162402X.2024.2338558

Antonio Tapia-Galisteo, Iñigo Sánchez-Rodríguez, Javier Narbona, Patricia Iglesias-Hernández, Saray Aragón-García, Anaïs Jiménez-Reinoso, Marta Compte, Shaukat Khan, Takeshi Tsuda, Patrick Chames, Javier Lacadena, Luis Álvarez-Vallina, Laura Sanz

发表日期：2024

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Nanobody-Based EGFR-Targeting Immunotoxins for Colorectal Cancer Treatment

基于纳米抗体的EGFR靶向免疫毒素用于结直肠癌治疗

期刊:Biomolecules

影响因子:4.8

doi:10.3390/biom13071042

Narbona, Javier; Hernández-Baraza, Luisa; Gordo, Rubén G; Sanz, Laura; Lacadena, Javier

免疫/内分泌

发表日期：2023

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A New Optimized Version of a Colorectal Cancer-Targeted Immunotoxin Based on a Non-Immunogenic Variant of the Ribotoxin α-Sarcin

一种基于非免疫原性核糖毒素α-沙雷氏菌素变体的新型优化结直肠癌靶向免疫毒素。

影响因子:4.4

doi:10.3390/cancers15041114

Narbona, Javier; Gordo, Rubén G; Tomé-Amat, Jaime; Lacadena, Javier

免疫/内分泌

发表日期：2023

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Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer

三特异性 T 细胞接合剂用于结直肠癌的双重肿瘤靶向

期刊:Oncoimmunology

doi:10.1080/2162402X.2022.2034355

Antonio Tapia-Galisteo, Íñigo Sánchez Rodríguez, Oscar Aguilar-Sopeña, Seandean Lykke Harwood, Javier Narbona, Mariola Ferreras Gutierrez, Rocío Navarro, Laura Martín-García, Cesáreo Corbacho, Marta Compte, Javier Lacadena, Francisco J Blanco, Patrick Chames, Pedro Roda-Navarro, Luis Álvarez-Vallina

发表日期：2022

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Antibody-Based Immunotoxins for Colorectal Cancer Therapy

基于抗体的免疫毒素用于结直肠癌治疗

期刊:Biomedicines

影响因子:3.9

doi:10.3390/biomedicines9111729

Sanz, Laura; Ibáñez-Pérez, Raquel; Guerrero-Ochoa, Patricia; Lacadena, Javier; Anel, Alberto

免疫/内分泌

发表日期：2021

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Der p 1-based immunotoxin as potential tool for the treatment of dust mite respiratory allergy

基于Der p 1的免疫毒素作为治疗尘螨呼吸道过敏的潜在工具

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-020-69166-w

Lázaro-Gorines, Rodrigo; López-Rodríguez, Juan Carlos; Benedé, Sara; González, Miguel; Mayorga, Cristobalina; Vogel, Lothar; Martínez-Del-Pozo, Álvaro; Lacadena, Javier; Villalba, Mayte

免疫/内分泌

发表日期：2020

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Inclusion of a Furin Cleavage Site Enhances Antitumor Efficacy against Colorectal Cancer Cells of Ribotoxin α-Sarcin- or RNase T1-Based Immunotoxins

引入弗林蛋白酶切割位点可增强核糖毒素α-沙雷氏菌素或RNase T1类免疫毒素对结直肠癌细胞的抗肿瘤疗效。

doi:10.3390/toxins11100593

Ruiz-de-la-Herrán, Javier; Tomé-Amat, Jaime; Lázaro-Gorines, Rodrigo; Gavilanes, José G; Lacadena, Javier

免疫/内分泌

细胞生物学

发表日期：2019

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A deimmunised form of the ribotoxin, α-sarcin, lacking CD4+ T cell epitopes and its use as an immunotoxin warhead

缺乏 CD4+ T 细胞表位的核糖毒素 α-sarcin 的去免疫形式及其作为免疫毒素弹头的用途

期刊:Protein Engineering Design & Selection

影响因子:2.6

doi:10.1093/protein/gzw045

Tim D Jones, Arron R Hearn, Robert G E Holgate, Dorota Kozub, Mark H Fogg, Francis J Carr, Matthew P Baker, Javier Lacadena, Kurt R Gehlsen

发表日期：2016

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