日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hematopoietic expression of cIAP2 drives inflammation and heart failure after myocardial infarction.

心肌梗死后,cIAP2 的造血表达会引发炎症和心力衰竭。

Smyth David, Zhang Liyong, Al-Khalaf Mohammad, Robichaud Sabrina, Seymour Richard, Geoffrion Michele, Jung Richard, Parlow Simon, Du Feng, McNeill Brian, Du Qiujiang, Beauregard Caroline, Zhao Xiaoling, Ouimet Mireille, Beug Shawn T, LaCasse Eric C, Rayner Katey J, Mak Tak W, Hibbert Benjamin, Korneluk Robert G, Liu Peter P

Enhanced glioblastoma immunotherapy via SMAC mimetic dose escalation and TGFβ blockade.

通过增加 SMAC 模拟物剂量和阻断 TGFβ 来增强胶质母细胞瘤免疫疗法。

Malone Kyle, Dugas Melanie, Earl Nathalie, Alain Tommy, Korneluk Robert G, LaCasse Eric, Beug Shawn T

Cell death in glioblastoma and the central nervous system

胶质母细胞瘤和中枢神经系统中的细胞死亡

Malone, Kyle; LaCasse, Eric; Beug, Shawn T

Xevinapant plus avelumab in advanced solid tumours, with a dose expansion in advanced non-small-cell lung cancer: exploratory biomarker, safety and efficacy analyses from an open-label, nonrandomised phase Ib study

Xevinapant联合avelumab治疗晚期实体瘤,并在晚期非小细胞肺癌中进行剂量扩展:一项开放标签、非随机Ib期研究的探索性生物标志物、安全性和疗效分析

Goss, Glenwood; Ciuleanu, Tudor; Ramlau, Rodryg; Renouf, Daniel J; Chu, Quincy; Kalinka, Ewa; Sawrycki, Piotr; Bramson, Jonathan; Nelson, Brad H; Crabbé, Rafael; LaCasse, Eric; Lo, Bryan; Sahlender, Daniela A; Crompton, Philippa; Brichory, Franck; Piggott, Luke; Schenker, Michael; Juergens, Rosalyn

Taking aim with IAP antagonists at triple-negative breast cancer: a moving target no more?

使用 IAP 拮抗剂治疗三阴性乳腺癌:不再是移动的目标了吗?

LaCasse, Eric C

Sp3-cificity of TNF-α expression promotes the Smac mimetic-mediated killing of cancer cells

TNF-α表达的特异性促进Smac模拟物介导的癌细胞杀伤作用

Beug, Shawn T; Korneluk, Robert G; LaCasse, Eric C

Smac mimetics combined with innate immune stimuli create the perfect cytokine storm to kill tumor cells

Smac 模拟物与先天免疫刺激相结合,可产生完美的细胞因子风暴,从而杀死肿瘤细胞。

Beug, Shawn T; LaCasse, Eric C; Korneluk, Robert G

Distinct role of calmodulin and calmodulin-dependent protein kinase-II in lipopolysaccharide and tumor necrosis factor-α-mediated suppression of apoptosis and antiapoptotic c-IAP2 gene expression in human monocytic cells

钙调蛋白和钙调蛋白依赖性蛋白激酶II在脂多糖和肿瘤坏死因子-α介导的人单核细胞凋亡抑制和抗凋亡基因c-IAP2表达中发挥着不同的作用

Mishra, Sasmita; Mishra, Jyoti P; Gee, Katrina; McManus, Dan C; LaCasse, Eric C; Kumar, Ashok

Phase I/II trial of AEG35156 X-linked inhibitor of apoptosis protein antisense oligonucleotide combined with idarubicin and cytarabine in patients with relapsed or primary refractory acute myeloid leukemia

AEG35156 X连锁凋亡蛋白反义寡核苷酸联合伊达比星和阿糖胞苷治疗复发或原发性难治性急性髓系白血病患者的I/II期临床试验

Schimmer, Aaron D; Estey, Elihu H; Borthakur, Gautam; Carter, Bing Z; Schiller, Gary J; Tallman, Martin S; Altman, Jessica K; Karp, Judith E; Kassis, Jeannine; Hedley, David W; Brandwein, Joseph; Xu, Wei; Mak, Duncan H; LaCasse, Eric; Jacob, Christine; Morris, Stephen J; Jolivet, Jacques; Andreeff, Michael

XIAP protection of photoreceptors in animal models of retinitis pigmentosa.

XIAP 对视网膜色素变性动物模型中感光细胞的保护作用

Leonard Kevin C, Petrin Dino, Coupland Stuart G, Baker Adam N, Leonard Brian C, LaCasse Eric C, Hauswirth William W, Korneluk Robert G, Tsilfidis Catherine