日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-cell atlas of AML reveals age-related gene regulatory networks in t(8;21) AML

AML单细胞图谱揭示了t(8;21) AML中与年龄相关的基因调控网络

Whittle, Jessica; Meyer, Stefan; Lacaud, Georges; Murtuza-Baker, Syed; Iqbal, Mudassar

Gfi1 controls the formation of effector-like CD8(+) T cells during chronic infection and cancer.

Gfi1 控制慢性感染和癌症期间效应样 CD8(+) T 细胞的形成

Ojo Oluwagbemiga A, Shen Hongxing, Ingram Jennifer T, Bonner James A, Welner Robert S, Lacaud Georges, Zajac Allan J, Shi Lewis Z

Competing dynamic gene regulatory networks involved in fibroblast reprogramming to hematopoietic progenitor cells

参与成纤维细胞重编程为造血祖细胞的竞争性动态基因调控网络

Shafiq, Samiyah; Hamashima, Kiyofumi; Guest, Laura A; Al-Anbaki, Ali H; Amaral, Fabio M R; Wiseman, Daniel H; Kouskoff, Valerie; Lacaud, Georges; Loh, Yuin-Han; Batta, Kiran

Single-cell profiling reveals three endothelial-to-hematopoietic transitions with divergent isoform expression landscapes

单细胞分析揭示了三种内皮细胞向造血细胞转变过程,每种转变过程都具有不同的亚型表达谱。

Neo, Wen Hao; Fadlullah, Muhammad Zaki Hidayatullah; Bhatnagar, Harshangda; Barone, Cristiana; Quattrini, Giulia; Timóteo-Ferreira, Filipa; Carrelha, Joana; Sala, Gianluca; Sellers, Robert; Weightman, John; Breitwieser, Wolfgang; Moncaut, Natalia; Thambyrajah, Roshana; Jacobsen, Sten Eirik W; Iqbal, Mudassar; Baker, Syed Murtuza; Azzoni, Emanuele; Lie-A-Ling, Michael; Lacaud, Georges

SGOL1-AS1 enhances cell survival in acute myeloid leukemia by maintaining pro-inflammatory signaling

SGOL1-AS1通过维持促炎信号通路增强急性髓系白血病细胞的存活率

Selkirk, Ewan; Patel, Rahima; Hoyle, Anna; Lie-A-Ling, Michael; Smith, Duncan; Swift, Joe; Lacaud, Georges

Contributions of Embryonic HSC-Independent Hematopoiesis to Organogenesis and the Adult Hematopoietic System

胚胎造血干细胞非依赖性造血对器官发生和成体造血系统的贡献

Neo, Wen Hao; Lie-A-Ling, Michael; Fadlullah, Muhammad Zaki Hidayatullah; Lacaud, Georges

RUNX1 Dosage in Development and Cancer

RUNX1 在发育和癌症中的剂量

Lie-A-Ling, Michael; Mevel, Renaud; Patel, Rahima; Blyth, Karen; Baena, Esther; Kouskoff, Valerie; Lacaud, Georges

Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells: An integrative approach using high-throughput datasets

利用高通量数据集进行整合方法,鉴定小鼠胚胎干细胞分化过程中基因特异性顺式调控元件

Vijayabaskar, M S; Goode, Debbie K; Obier, Nadine; Lichtinger, Monika; Emmett, Amber M L; Abidin, Fatin N Zainul; Shar, Nisar; Hannah, Rebecca; Assi, Salam A; Lie-A-Ling, Michael; Gottgens, Berthold; Lacaud, Georges; Kouskoff, Valerie; Bonifer, Constanze; Westhead, David R

Transcriptional control of blood cell emergence

血细胞出现的转录调控

Menegatti, Sara; de Kruijf, Marcel; Garcia-Alegria, Eva; Lacaud, Georges; Kouskoff, Valerie

Regulation of RUNX1 dosage is crucial for efficient blood formation from hemogenic endothelium

RUNX1剂量的调控对于造血内皮细胞高效造血至关重要。

Lie-A-Ling, Michael; Marinopoulou, Elli; Lilly, Andrew J; Challinor, Mairi; Patel, Rahima; Lancrin, Christophe; Kouskoff, Valerie; Lacaud, Georges