日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication

经 CCR5 编辑的 CD4+ T 细胞可增强 HIV 特异性免疫力,从而实现 HIV 病毒反弹后复制的控制。

Tebas, Pablo; Jadlowsky, Julie K; Shaw, Pamela A; Tian, Lifeng; Esparza, Erin; Brennan, Andrea L; Kim, Sukyung; Naing, Soe Yu; Richardson, Max W; Vogel, Ashley N; Maldini, Colby R; Kong, Hong; Liu, Xiaojun; Lacey, Simon F; Bauer, Anya M; Mampe, Felicity; Richman, Lee P; Lee, Gary; Ando, Dale; Levine, Bruce L; Porter, David L; Zhao, Yangbing; Siegel, Don L; Bar, Katharine J; June, Carl H; Riley, James L

Two cases of severe pulmonary toxicity from highly active mesothelin-directed CAR T cells

两例由高活性间皮素靶向CAR-T细胞引起的严重肺毒性病例

Haas, Andrew R; Golden, Ryan J; Litzky, Leslie A; Engels, Boris; Zhao, Linlin; Xu, Fangmin; Taraszka, John A; Ramones, Melissa; Granda, Brian; Chang, Wan-Jung; Jadlowsky, Julie; Shea, Kim-Marie; Runkle, Adam; Chew, Anne; Dowd, Emily; Gonzalez, Vanessa; Chen, Fang; Liu, Xiaojun; Fang, Chongyun; Jiang, Shuguang; Davis, Megan M; Sheppard, Neil C; Zhao, Yangbing; Fraietta, Joseph A; Lacey, Simon F; Plesa, Gabriela; Melenhorst, J Joseph; Mansfield, Keith; Brogdon, Jennifer L; Young, Regina M; Albelda, Steven M; June, Carl H; Tanyi, Janos L

Changes in Bone Marrow Tumor and Immune Cells Correlate with Durability of Remissions Following BCMA CAR T Therapy in Myeloma

骨髓肿瘤和免疫细胞的变化与骨髓瘤患者接受BCMA CAR-T疗法后缓解期的持久性相关

Dhodapkar, Kavita M; Cohen, Adam D; Kaushal, Akhilesh; Garfall, Alfred L; Manalo, Renee Julia; Carr, Allison R; McCachren, Samuel S; Stadtmauer, Edward A; Lacey, Simon F; Melenhorst, J Joseph; June, Carl H; Milone, Michael C; Dhodapkar, Madhav V

Anti-CD19 CAR T cells in combination with ibrutinib for the treatment of chronic lymphocytic leukemia

抗CD19 CAR T细胞联合伊布替尼治疗慢性淋巴细胞白血病

Gill, Saar; Vides, Vanessa; Frey, Noelle V; Hexner, Elizabeth O; Metzger, Susan; O'Brien, Megan; Hwang, Wei-Ting; Brogdon, Jennifer L; Davis, Megan M; Fraietta, Joseph A; Gaymon, Avery L; Gladney, Whitney L; Lacey, Simon F; Lamontagne, Anne; Mato, Anthony R; Maus, Marcela V; Melenhorst, J Joseph; Pequignot, Edward; Ruella, Marco; Shestov, Maksim; Byrd, John C; Schuster, Stephen J; Siegel, Donald L; Levine, Bruce L; June, Carl H; Porter, David L

PD1 Expression in EGFRvIII-Directed CAR T Cell Infusion Product for Glioblastoma Is Associated with Clinical Response

胶质母细胞瘤EGFRvIII靶向CAR-T细胞输注产品中PD1表达与临床疗效相关

Tang, Oliver Y; Tian, Lifeng; Yoder, Todd; Xu, Rong; Kulikovskaya, Irina; Gupta, Minnal; Melenhorst, Jan Joseph; Lacey, Simon F; O'Rourke, Donald M; Binder, Zev A

Temperature Trajectory Sub-phenotypes and the Immuno-Inflammatory Response in Pediatric Sepsis

儿童脓毒症中体温轨迹亚表型与免疫炎症反应的关系

Yehya, Nadir; Fitzgerald, Julie C; Hayes, Katie; Zhang, Donglan; Bush, Jenny; Koterba, Natalka; Chen, Fang; Tuluc, Florin; Teachey, David T; Balamuth, Fran; Lacey, Simon F; Melenhorst, Jan Joseph; Weiss, Scott L

Humanized CD19-Targeted Chimeric Antigen Receptor (CAR) T Cells in CAR-Naive and CAR-Exposed Children and Young Adults With Relapsed or Refractory Acute Lymphoblastic Leukemia

在复发或难治性急性淋巴细胞白血病的儿童和青少年中,人源化 CD19 靶向嵌合抗原受体 (CAR) T 细胞治疗未接受过 CAR 治疗和接受过 CAR 治疗的儿童和青少年。

Myers, Regina M; Li, Yimei; Barz Leahy, Allison; Barrett, David M; Teachey, David T; Callahan, Colleen; Fasano, Christina C; Rheingold, Susan R; DiNofia, Amanda; Wray, Lisa; Aplenc, Richard; Baniewicz, Diane; Liu, Hongyan; Shaw, Pamela A; Pequignot, Edward; Getz, Kelly D; Brogdon, Jennifer L; Fesnak, Andrew D; Siegel, Donald L; Davis, Megan M; Bartoszek, Chelsie; Lacey, Simon F; Hexner, Elizabeth O; Chew, Anne; Wertheim, Gerald B; Levine, Bruce L; June, Carl H; Grupp, Stephan A; Maude, Shannon L

Risk-Adapted Preemptive Tocilizumab to Prevent Severe Cytokine Release Syndrome After CTL019 for Pediatric B-Cell Acute Lymphoblastic Leukemia: A Prospective Clinical Trial

风险适应性预防性托珠单抗治疗预防儿童B细胞急性淋巴细胞白血病CTL019治疗后严重细胞因子释放综合征:一项前瞻性临床试验

Kadauke, Stephan; Myers, Regina M; Li, Yimei; Aplenc, Richard; Baniewicz, Diane; Barrett, David M; Barz Leahy, Allison; Callahan, Colleen; Dolan, Joseph G; Fitzgerald, Julie C; Gladney, Whitney; Lacey, Simon F; Liu, Hongyan; Maude, Shannon L; McGuire, Regina; Motley, Laura S; Teachey, David T; Wertheim, Gerald B; Wray, Lisa; DiNofia, Amanda M; Grupp, Stephan A

BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia

BET溴结构域蛋白抑制可逆转嵌合抗原受体的消亡,并重新激活慢性淋巴细胞白血病中耗竭的T细胞。

Kong, Weimin; Dimitri, Alexander; Wang, Wenliang; Jung, In-Young; Ott, Christopher J; Fasolino, Maria; Wang, Yan; Kulikovskaya, Irina; Gupta, Minnal; Yoder, Todd; DeNizio, Jamie E; Everett, John K; Williams, Erik F; Xu, Jun; Scholler, John; Reich, Tyler J; Bhoj, Vijay G; Haines, Kathleen M; Maus, Marcela V; Melenhorst, J Joseph; Young, Regina M; Jadlowsky, Julie K; Marcucci, Katherine T; Bradner, James E; Levine, Bruce L; Porter, David L; Bushman, Frederic D; Kohli, Rahul M; June, Carl H; Davis, Megan M; Lacey, Simon F; Vahedi, Golnaz; Fraietta, Joseph A

The Safety of Bridging Radiation with Anti-BCMA CAR T-Cell Therapy for Multiple Myeloma

多发性骨髓瘤患者接受抗BCMA CAR T细胞疗法桥接放疗的安全性

Manjunath, Shwetha H; Cohen, Adam D; Lacey, Simon F; Davis, Megan M; Garfall, Alfred L; Melenhorst, J Joseph; Maxwell, Russell; Arscott, W Tristram; Maity, Amit; Jones, Joshua A; Plastaras, John P; Stadtmauer, Edward A; Levine, Bruce L; June, Carl H; Milone, Michael C; Paydar, Ima