日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Clinical evidence of immunogenicity of CAR-T cell therapies and its implication in the clinical development of CAR-T drug products

CAR-T细胞疗法免疫原性的临床证据及其在CAR-T药物产品临床开发中的意义

Alfar, Hammodah R; Chen, Cecil; Lachacz, Eric; Tang, Weifeng; Zhang, Yuqian

Development of production methodologies for scFv-Fc conjugated critical reagents to support CAR-T clinical programs

开发用于生产scFv-Fc偶联关键试剂以支持CAR-T临床项目的生产方法

O'Connor, Ellen; Lachacz, Eric; Delmar, Jared; D'souza, Bradley; Edwards, Samuel; Griffin, Christopher; Lin, Rosie; Mody, Neil; Salas, Alicia; Schoch-Lopez, Natalia; Shah, Mitali; Shih, Ai; van Dyk, Dewald; Xu, Yueming

Insights into the modular design of kinase inhibitors and application to Abl and Axl

深入探讨激酶抑制剂的模块化设计及其在 Abl 和 Axl 中的应用

Phadke, Sameer; Lopez-Barcons, Lluis; Vandecan, Nathalie; Wu, Zhifen; Johnson, Taylor K; Lachacz, Eric J; Merajver, Sofia D; Soellner, Matthew B

Molecular determinants of drug response in TNBC cell lines

TNBC 细胞系药物反应的分子决定因素

Nathan M Merrill, Eric J Lachacz, Nathalie M Vandecan, Peter J Ulintz, Liwei Bao, John P Lloyd, Joel A Yates, Aki Morikawa, Sofia D Merajver, Matthew B Soellner

Selective Proteolysis to Study the Global Conformation and Regulatory Mechanisms of c-Src Kinase

利用选择性蛋白水解研究c-Src激酶的整体构象和调控机制

Agius, Michael P; Ko, Kristin S; Johnson, Taylor K; Kwarcinski, Frank E; Phadke, Sameer; Lachacz, Eric J; Soellner, Matthew B

Population Effect of Differences in Cholesterol Guidelines in Eastern Europe and the United States

东欧和美国胆固醇指南差异对人群的影响

Lee, Jerry C; Zdrojewski, Tomasz; Pencina, Michael J; Wyszomirski, Adam; Lachacz, Mateusz; Opolski, Grzegorz; Bandosz, Piotr; Rutkowski, Marcin; Gaciong, Zbigniew; Wyrzykowski, Bogdan; Navar, Ann M

Exquisitely specific bisubstrate inhibitors of c-Src kinase

c-Src激酶的特异性极高的双底物抑制剂

Brandvold, Kristoffer R; Santos, Shana M; Breen, Meghan E; Lachacz, Eric J; Steffey, Michael E; Soellner, Matthew B

Substrate activity screening with kinases: discovery of small-molecule substrate-competitive c-Src inhibitors

利用激酶进行底物活性筛选:发现小分子底物竞争性 c-Src 抑制剂

Breen, Meghan E; Steffey, Michael E; Lachacz, Eric J; Kwarcinski, Frank E; Fox, Christel C; Soellner, Matthew B

Influence of aromatase inhibition on the bone-protective effects of testosterone

芳香化酶抑制对睾酮骨保护作用的影响

Beck, Darren T; Yarrow, Joshua F; Beggs, Luke A; Otzel, Dana M; Ye, Fan; Conover, Christine F; Miller, Julie R; Balaez, Alexander; Combs, Sarah M; Leeper, Alicia M; Williams, Alyssa A; Lachacz, Stephanie A; Zheng, Nigel; Wronski, Thomas J; Borst, Stephen E