日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.

人类 NuA4/TIP60 乙酰转移酶和染色质重塑复合物的结构解析

Yang Zhenlin, Mameri Amel, Cattoglio Claudia, Lachance Catherine, Florez Ariza Alfredo Jose, Luo Jie, Humbert Jonathan, Sudarshan Deepthi, Banerjea Arul, Galloy Maxime, Fradet-Turcotte Amélie, Lambert Jean-Philippe, Ranish Jeff A, Côté Jacques, Nogales Eva

Guiding the HBO1 complex function through the JADE subunit.

通过 JADE 亚基引导 HBO1 复合物发挥功能

Gaurav Nitika, Kanai Akinori, Lachance Catherine, Cox Khan L, Liu Jiuyang, Grzybowski Adrian T, Saksouk Nehmé, Klein Brianna J, Komata Yosuke, Asada Shuhei, Ruthenburg Alexander J, Poirier Michael G, Côté Jacques, Yokoyama Akihiko, Kutateladze Tatiana G

Recurrent chromosomal translocations in sarcomas create a megacomplex that mislocalizes NuA4/TIP60 to Polycomb target loci

肉瘤中反复发生的染色体易位形成巨型复合物,导致 NuA4/TIP60 错误定位到 Polycomb 靶位点。

Sudarshan, Deepthi; Avvakumov, Nikita; Lalonde, Marie-Eve; Alerasool, Nader; Joly-Beauparlant, Charles; Jacquet, Karine; Mameri, Amel; Lambert, Jean-Philippe; Rousseau, Justine; Lachance, Catherine; Paquet, Eric; Herrmann, Lara; Thonta Setty, Samarth; Loehr, Jeremy; Bernardini, Marcus Q; Rouzbahman, Marjan; Gingras, Anne-Claude; Coulombe, Benoit; Droit, Arnaud; Taipale, Mikko; Doyon, Yannick; Côté, Jacques

The scaffolding protein JADE1 physically links the acetyltransferase subunit HBO1 with its histone H3-H4 substrate

支架蛋白JADE1将乙酰转移酶亚基HBO1与其组蛋白H3-H4底物进行物理连接。

Han, Joseph; Lachance, Catherine; Ricketts, M Daniel; McCullough, Cheryl E; Gerace, Morgan; Black, Ben E; Côté, Jacques; Marmorstein, Ronen