Lackey Lela相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Conservation of extended sequence and structure in the branchpoint-to-3' splice site region upstream of neural microexons

神经微外显子上游分支点至3'剪接位点区域的延伸序列和结构保守性

doi:10.64898/2026.01.16.699960

Randazza, Alexandra; Howe, Kathryn E; McCoy, John R; Hatfield, Abigail; Doucet-O'Hare, Tara; Lackey, Lela

发表日期：2026

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Altered polyadenylation site usage in SERPINA1 3'UTR in response to cellular stress affects A1AT protein expression.

细胞应激反应中 SERPINA1 3'UTR 中多聚腺苷酸化位点的改变会影响 A1AT 蛋白的表达

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-07569-3

Jiamutai F N U, Hatfield Abigail, Herbert Austin, Majumdar Debarati, Shankar Vijay, Lackey Lela

细胞生物学

发表日期：2025

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Precursor RNA structural patterns at SF3B1 mutation sensitive cryptic 3' splice sites

SF3B1突变敏感的隐蔽3'剪接位点的前体RNA结构模式

doi:10.1101/2025.02.19.638873

Herbert, Austin; Hatfield, Abigail; Randazza, Alexandra; Miyamoto, Valeria; Palmer, Katie; Lackey, Lela

发表日期：2025

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How does precursor RNA structure influence RNA processing and gene expression?

前体RNA结构如何影响RNA加工和基因表达？

期刊:Bioscience Reports

影响因子:4.7

doi:10.1042/BSR20220149

Herbert, Austin; Hatfield, Abigail; Lackey, Lela

发表日期：2023

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Global 5'-UTR RNA structure regulates translation of a SERPINA1 mRNA

全球5'-UTR RNA结构调控SERPINA1 mRNA的翻译

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkac739

Grayeski, Philip J; Weidmann, Chase A; Kumar, Jayashree; Lackey, Lela; Mustoe, Anthony M; Busan, Steven; Laederach, Alain; Weeks, Kevin M

发表日期：2022

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Quantitative prediction of variant effects on alternative splicing in MAPT using endogenous pre-messenger RNA structure probing

利用内源性前体信使RNA结构探测对MAPT中变异体对选择性剪接的影响进行定量预测

影响因子:6.4

doi:10.7554/eLife.73888

Kumar, Jayashree; Lackey, Lela; Waldern, Justin M; Dey, Abhishek; Mustoe, Anthony M; Weeks, Kevin M; Mathews, David H; Laederach, Alain

发表日期：2022

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Alternative poly-adenylation modulates α1-antitrypsin expression in chronic obstructive pulmonary disease

替代性多聚腺苷酸化调节慢性阻塞性肺疾病中α1-抗胰蛋白酶的表达

期刊:PLoS Genetics

影响因子:3.7

doi:10.1371/journal.pgen.1009912

Lackey, Lela; Coria, Aaztli; Ghosh, Auyon J; Grayeski, Phil; Hatfield, Abigail; Shankar, Vijay; Platig, John; Xu, Zhonghui; Ramos, Silvia B V; Silverman, Edwin K; Ortega, Victor E; Cho, Michael H; Hersh, Craig P; Hobbs, Brian D; Castaldi, Peter; Laederach, Alain

慢性阻塞性肺疾病

发表日期：2021

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The Effects of Rare SERPINA1 Variants on Lung Function and Emphysema in SPIROMICS

罕见SERPINA1变异对SPIROMICS患者肺功能和肺气肿的影响

期刊:American Journal of Respiratory and Critical Care Medicine

影响因子:19.4

doi:10.1164/rccm.201904-0769OC

Ortega, Victor E; Li, Xingnan; O'Neal, Wanda K; Lackey, Lela; Ampleford, Elizabeth; Hawkins, Gregory A; Grayeski, Philip J; Laederach, Alain; Barjaktarevic, Igor; Barr, R Graham; Cooper, Christopher; Couper, David; Han, MeiLan K; Kanner, Richard E; Kleerup, Eric C; Martinez, Fernando J; Paine, Robert 3rd; Peters, Stephen P; Pirozzi, Cheryl; Rennard, Stephen I; Woodruff, Prescott G; Hoffman, Eric A; Meyers, Deborah A; Bleecker, Eugene R

发表日期：2020

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Comparative Visualization of the RNA Suboptimal Conformational Ensemble In Vivo

体内RNA次优构象集合的比较可视化

期刊:Biophysical Journal

影响因子:3.1

doi:10.1016/j.bpj.2017.05.031

Woods, Chanin T; Lackey, Lela; Williams, Benfeard; Dokholyan, Nikolay V; Gotz, David; Laederach, Alain

发表日期：2017

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Increased Transcript Complexity in Genes Associated with Chronic Obstructive Pulmonary Disease

慢性阻塞性肺病相关基因的转录本复杂性增加

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0140885

Lackey, Lela; McArthur, Evonne; Laederach, Alain

发表日期：2015

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