日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

mRNA stability fine-tunes gene expression in the developing cortex to control neurogenesis

mRNA稳定性精细调控发育中皮层的基因表达,从而控制神经发生。

Lucas D Serdar ,Jacob R Egol ,Brad Lackford ,Brian D Bennett ,Guang Hu ,Debra L Silver

Cnot3 is required for male germ cell development and spermatogonial stem cell maintenance.

Cnot3 是雄性生殖细胞发育和精原干细胞维持所必需的

Chen Qing, Malki Safia, Xu Xiaojiang, Wang Jiajia, Bennett Brian, Zheng Xiaofeng, Lackford Brad L, Kirsanov Oleksandr, Geyer Christopher B, Hu Guang

Dissecting the Role of the Ccr4-Not Deadenylase Complex in Pluripotency and Differentiation

解析 Ccr4-Not 脱腺苷酸酶复合物在多能性和分化中的作用

Xiukun Wang, Qing Chen, Brad Lackford, Guang Hu

Retinoic acid is dispensable for meiotic initiation but required for spermiogenesis in the mammalian testis

视黄酸对于减数分裂起始不是必需的,但对于哺乳动物睾丸中的精子发生是必需的

Oleksandr Kirsanov, Taylor A Johnson, Bryan A Niedenberger, Taylor N Malachowski, Benjamin J Hale, Qing Chen, Brad Lackford, Jiajia Wang, Anukriti Singh, Karen Schindler, Brian P Hermann, Guang Hu, Christopher B Geyer

Cnot3 is required for male germ cell development and spermatogonial stem cell maintenance

Cnot3 是男性生殖细胞发育和精原干细胞维持所必需的

Qing Chen, Safia Malki, Xiaojiang Xu, Brian Bennett, Brad L Lackford, Oleksandr Kirsanov, Christopher B Geyer, Guang Hu

INO80 promotes H2A.Z occupancy to regulate cell fate transition in pluripotent stem cells

INO80 促进 H2A.Z 占据调控多能干细胞命运转变

Hongyao Yu, Jiajia Wang, Brad Lackford, Brian Bennett, Jian-Liang Li, Guang Hu

CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State

CNOT3 依赖的 mRNA 脱腺苷酸化保障多能状态

Xiaofeng Zheng, Pengyi Yang, Brad Lackford, Brian D Bennett, Li Wang, Hui Li, Yu Wang, Yiliang Miao, Julie F Foley, David C Fargo, Ying Jin, Carmen J Williams, Raja Jothi, Guang Hu

A Serial shRNA Screen for Roadblocks to Reprogramming Identifies the Protein Modifier SUMO2

通过一系列shRNA筛选,我们发现了阻碍重编程的蛋白质修饰因子SUMO2。

Marti Borkent ,Brian D Bennett ,Brad Lackford ,Ori Bar-Nur ,Justin Brumbaugh ,Li Wang ,Ying Du ,David C Fargo ,Effie Apostolou ,Sihem Cheloufi ,Nimet Maherali ,Stephen J Elledge ,Guang Hu ,Konrad Hochedlinger

INO80 facilitates pluripotency gene activation in embryonic stem cell self-renewal, reprogramming, and blastocyst development

INO80 促进胚胎干细胞自我更新、重编程和囊胚发育中的多能性基因激活

Li Wang, Ying Du, James M Ward, Takashi Shimbo, Brad Lackford, Xiaofeng Zheng, Yi-liang Miao, Bingying Zhou, Leng Han, David C Fargo, Raja Jothi, Carmen J Williams, Paul A Wade, Guang Hu

Fip1 regulates mRNA alternative polyadenylation to promote stem cell self-renewal

Fip1通过调控mRNA选择性多聚腺苷酸化促进干细胞自我更新

Lackford, Brad; Yao, Chengguo; Charles, Georgette M; Weng, Lingjie; Zheng, Xiaofeng; Choi, Eun-A; Xie, Xiaohui; Wan, Ji; Xing, Yi; Freudenberg, Johannes M; Yang, Pengyi; Jothi, Raja; Hu, Guang; Shi, Yongsheng