日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Optimization of diastereomeric dihydropyridines as antimalarials

优化非对映异构二氢吡啶类化合物作为抗疟药

Van Horn, Kurt S; Zhao, Yingzhao; Parvatkar, Prakash T; Maier, Julie; Mutka, Tina; Lacrue, Alexis; Brockmeier, Fabian; Ebert, Daniel; Wu, Wesley; Casandra, Debora R; Namelikonda, Niranjan; Yacoub, Jeanine; Sigal, Martina; Knapp, Spencer; Floyd, David; Waterson, David; Burrows, Jeremy N; Duffy, James; DeRisi, Joseph L; Kyle, Dennis E; Guy, R Kiplin; Manetsch, Roman

Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium

口服生物利用度高的6-氯-7-甲氧基-4(1H)-喹诺酮类药物对疟原虫的多个发育阶段均有效

Cross, R Matthew; Flanigan, David L; Monastyrskyi, Andrii; LaCrue, Alexis N; Sáenz, Fabián E; Maignan, Jordany R; Mutka, Tina S; White, Karen L; Shackleford, David M; Bathurst, Ian; Fronczek, Frank R; Wojtas, Lukasz; Guida, Wayne C; Charman, Susan A; Burrows, Jeremy N; Kyle, Dennis E; Manetsch, Roman

Fatty acid synthesis and pyruvate metabolism pathways remain active in dihydroartemisinin-induced dormant ring stages of Plasmodium falciparum

在双氢青蒿素诱导的恶性疟原虫休眠环状体阶段,脂肪酸合成和丙酮酸代谢途径仍然活跃。

Chen, Nanhua; LaCrue, Alexis N; Teuscher, Franka; Waters, Norman C; Gatton, Michelle L; Kyle, Dennis E; Cheng, Qin

Quinolone-3-diarylethers: a new class of antimalarial drug

喹诺酮-3-二芳基醚:一类新型抗疟药

Nilsen, Aaron; LaCrue, Alexis N; White, Karen L; Forquer, Isaac P; Cross, Richard M; Marfurt, Jutta; Mather, Michael W; Delves, Michael J; Shackleford, David M; Saenz, Fabian E; Morrisey, Joanne M; Steuten, Jessica; Mutka, Tina; Li, Yuexin; Wirjanata, Grennady; Ryan, Eileen; Duffy, Sandra; Kelly, Jane Xu; Sebayang, Boni F; Zeeman, Anne-Marie; Noviyanti, Rintis; Sinden, Robert E; Kocken, Clemens H M; Price, Ric N; Avery, Vicky M; Angulo-Barturen, Iñigo; Jiménez-Díaz, María Belén; Ferrer, Santiago; Herreros, Esperanza; Sanz, Laura M; Gamo, Francisco-Javier; Bathurst, Ian; Burrows, Jeremy N; Siegl, Peter; Guy, R Kiplin; Winter, Rolf W; Vaidya, Akhil B; Charman, Susan A; Kyle, Dennis E; Manetsch, Roman; Riscoe, Michael K

4-(1H)-Quinolones and 1,2,3,4-Tetrahydroacridin-9(10H)-ones prevent the transmission of Plasmodium falciparum to Anopheles freeborni

4-(1H)-喹诺酮和1,2,3,4-四氢吖啶-9(10H)-酮可阻止恶性疟原虫向弗里伯恩按蚊的传播。

Sáenz, Fabián E; Lacrue, Alexis N; Cross, R Matthew; Maignan, Jordany R; Udenze, Kenneth O; Manetsch, Roman; Kyle, Dennis E

Expression profile of the Plasmodium falciparum intra-erythrocytic stage protein, PF3D7_1363700

恶性疟原虫红细胞内期蛋白PF3D7_1363700的表达谱

Roberts, Renee N; Schlarman, Maggie S; Kariuki, Michael M; Lacrue, Alexis N; Ou, Ruguang; Beerntsen, Brenda T

Transcript and protein expression profile of PF11_0394, a Plasmodium falciparum protein expressed in salivary gland sporozoites

PF11_0394 的转录本和蛋白质表达谱,PF11_0394 是一种在唾液腺子孢子中表达的恶性疟原虫蛋白

Maggie S Schlarman, Renee N Roberts, Michael M Kariuki, Alexis N LaCrue, Ruguang Ou, Brenda T Beerntsen

PFE0565w, a Plasmodium falciparum protein expressed in salivary gland sporozoites

PFE0565w,一种在恶性疟原虫唾液腺子孢子中表达的蛋白质。

Schlarman, Maggie S; Roberts, Renee N; Kariuki, Michael M; LaCrue, Alexis N; Ou, Ruguang; Beerntsen, Brenda T