日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reduction in Cold Stress in an Innovative Metabolic Cage Housing System Increases Animal Welfare in Laboratory Mice

创新代谢笼养系统减少冷应激可提高实验室小鼠的动物福利

Laura Wittek, Chadi Touma, Tina Nitezki, Thomas Laeger, Stephanie Krämer, Jens Raila

The ARFRP1-dependent Golgi scaffolding protein GOPC is required for insulin secretion from pancreatic β-cells

ARFRP1 依赖的高尔基支架蛋白 GOPC 是胰腺 β 细胞分泌胰岛素所必需的

Ilka Wilhelmi, Stephan Grunwald, Niclas Gimber, Oliver Popp, Gunnar Dittmar, Anup Arumughan, Erich E Wanker, Thomas Laeger, Jan Schmoranzer, Oliver Daumke, Annette Schürmann

FGF21, not GCN2, influences bone morphology due to dietary protein restrictions

FGF21而非GCN2会影响膳食蛋白质限制引起的骨骼形态变化。

McNulty, Margaret A; Goupil, Brad A; Albarado, Diana C; Castaño-Martinez, Teresa; Ambrosi, Thomas H; Puh, Spela; Schulz, Tim J; Schürmann, Annette; Morrison, Christopher D; Laeger, Thomas

FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism

FGF21 向大脑发出蛋白质状态信号并自适应地调节食物选择和代谢

Cristal M Hill, Thomas Laeger, Madeleine Dehner, Diana C Albarado, Blaise Clarke, Desiree Wanders, Susan J Burke, J Jason Collier, Emily Qualls-Creekmore, Samantha M Solon-Biet, Stephen J Simpson, Hans-Rudolf Berthoud, Heike Münzberg, Christopher D Morrison

Reduced Oxidative Stress and Enhanced FGF21 Formation in Livers of Endurance-Exercised Rats with Diet-Induced NASH

饮食诱发 NASH 的耐力训练大鼠肝脏中氧化应激减少,FGF21 形成增强

Janin Henkel, Katja Buchheim-Dieckow, José P Castro, Thomas Laeger, Kristina Wardelmann, André Kleinridders, Korinna Jöhrens, Gerhard P Püschel

Epigenetic regulation of hepatic Dpp4 expression in response to dietary protein

饮食蛋白质对肝脏 Dpp4 表达的表观遗传调控

Sophie Saussenthaler, Meriem Ouni, Christian Baumeier, Kristin Schwerbel, Pascal Gottmann, Sabrina Christmann, Thomas Laeger, Annette Schürmann

Methionine restriction prevents onset of type 2 diabetes in NZO mice

限制蛋氨酸可预防 NZO 小鼠患上 2 型糖尿病

Teresa Castaño-Martinez, Fabian Schumacher, Silke Schumacher, Bastian Kochlik, Daniela Weber, Tilman Grune, Ronald Biemann, Adrian McCann, Klaus Abraham, Cornelia Weikert, Burkhard Kleuser, Annette Schürmann, Thomas Laeger

Dietary carbohydrates impair the protective effect of protein restriction against diabetes in NZO mice used as a model of type 2 diabetes

饮食中的碳水化合物会削弱蛋白质限制对 NZO 小鼠(作为 2 型糖尿病模型)的糖尿病保护作用

Thomas Laeger, Teresa Castaño-Martinez, Martin W Werno, Lukasz Japtok, Christian Baumeier, Wenke Jonas, Burkhard Kleuser, Annette Schürmann

FGF21 improves glucose homeostasis in an obese diabetes-prone mouse model independent of body fat changes

FGF21 可改善肥胖糖尿病易感小鼠模型中的葡萄糖稳态,且与体脂变化无关

Thomas Laeger, Christian Baumeier, Ilka Wilhelmi, Josefine Würfel, Anne Kamitz, Annette Schürmann

Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease

肝脏 DPP4 活性升高会促进胰岛素抵抗和非酒精性脂肪肝疾病

Christian Baumeier, Luisa Schlüter, Sophie Saussenthaler, Thomas Laeger, Maria Rödiger, Stella Amelie Alaze, Louise Fritsche, Hans-Ulrich Häring, Norbert Stefan, Andreas Fritsche, Robert Wolfgang Schwenk, Annette Schürmann