Limonoid compounds inhibit sphingomyelin biosynthesis by preventing CERT protein-dependent extraction of ceramides from the endoplasmic reticulum
柠檬苦素类化合物通过阻止CERT蛋白依赖的神经酰胺从内质网中提取,从而抑制鞘磷脂的生物合成。
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M112.344432
Hullin-Matsuda, Françoise; Tomishige, Nario; Sakai, Shota; Ishitsuka, Reiko; Ishii, Kumiko; Makino, Asami; Greimel, Peter; Abe, Mitsuhiro; Laviad, Elad L; Lagarde, Michel; Vidal, Hubert; Saito, Tamio; Osada, Hiroyuki; Hanada, Kentaro; Futerman, Anthony H; Kobayashi, Toshihide