日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mesothelioma location influences the tumour microenvironment and immune checkpoint therapy response in preclinical models

间皮瘤的位置会影响临床前模型中的肿瘤微环境和免疫检查点疗法反应。

Orozco Morales, M Lizeth; Lansley, Sally M; Chin, Wee Loong; Tilsed, Caitlin M; Principe, Nicola; Leslie, Connull; Vitali, Breana J; Rwandamuriye, Francois X; de Jong, Emma; Kidman, Joel; Zemek, Rachael M; Rinaldi, Catherine A; Lassmann, Timo; Bosco, Anthony; Lee, Y C Gary; Lake, Richard A; Chee, Jonathan; Lesterhuis, W Joost

Comparative analysis of malignant pleural effusion and peripheral blood reveals unique T cell signatures associated with survival in mesothelioma patients

恶性胸腔积液和外周血的比较分析揭示了与间皮瘤患者生存相关的独特T细胞特征

Principe, Nicola; Stevens, Kofi L P; Phung, Amber-Lee; McCoy, Melanie; Kidman, Joel; Ismail, Ali; Cook, Alistair M; Chopra, Abha; Watson, Mark; Robinson, Bruce W; Creaney, Jenette; Lee, Y C Gary; Waithman, Jason; Lesterhuis, W Joost; Lake, Richard A; Nowak, Anna K; Chee, Jonathan; McDonnell, Alison M

Coupling of response biomarkers between tumor and peripheral blood in patients undergoing chemoimmunotherapy.

接受化疗免疫治疗的患者肿瘤和外周血中反应生物标志物的耦合

Chin Wee Loong, Cook Alistair M, Chee Jonathan, Principe Nicola, Hoang Tracy S, Kidman Joel, Hmon Khaing P W, Yeow Yen, Jones Matthew E, Hou Rui, Denisenko Elena, McDonnell Alison M, Hon Chung-Chau, Moody Jonathan, Anderson Denise, Yip Sonia, Cummins Michelle M, Stockler Martin R, Kok Peey-Sei, Brown Chris, John Thomas, Kao Steven C-H, Karikios Deme J, O'Byrne Kenneth J, Hughes Brett G M, Lake Richard A, Forrest Alistair R R, Nowak Anna K, Lassmann Timo, Lesterhuis W Joost

The MexTAg collaborative cross: host genetics affects asbestos related disease latency, but has little influence once tumours develop

MexTAg合作研究发现:宿主遗传因素会影响石棉相关疾病的潜伏期,但对肿瘤发展后的影响甚微。

Fisher, Scott A; Patrick, Kimberley; Hoang, Tracy; Marcq, Elly; Behrouzfar, Kiarash; Young, Sylvia; Miller, Timothy J; Robinson, Bruce W S; Bueno, Raphael; Nowak, Anna K; Lesterhuis, W Joost; Morahan, Grant; Lake, Richard A

Tretinoin improves the anti-cancer response to cyclophosphamide, in a model-selective manner

维甲酸以模型选择性方式增强环磷酰胺的抗癌反应。

Tilsed, Caitlin M; Morales, M Lizeth Orozco; Zemek, Rachael M; Gordon, Brianna A; Piggott, Matthew J; Nowak, Anna K; Fisher, Scott A; Lake, Richard A; Lesterhuis, W Joost

Comprehensive Testing of Chemotherapy and Immune Checkpoint Blockade in Preclinical Cancer Models Identifies Additive Combinations

在临床前癌症模型中对化疗和免疫检查点阻断进行全面测试,发现了叠加组合疗法

Principe, Nicola; Aston, Wayne J; Hope, Danika E; Tilsed, Caitlin M; Fisher, Scott A; Boon, Louis; Dick, Ian M; Chin, Wee Loong; McDonnell, Alison M; Nowak, Anna K; Lake, Richard A; Chee, Jonathan; Lesterhuis, Willem Joost

Retinoic Acid Induces an IFN-Driven Inflammatory Tumour Microenvironment, Sensitizing to Immune Checkpoint Therapy

维甲酸诱导IFN驱动的炎症性肿瘤微环境,从而增强对免疫检查点疗法的敏感性

Tilsed, Caitlin M; Casey, Thomas H; de Jong, Emma; Bosco, Anthony; Zemek, Rachael M; Salmons, Joanne; Wan, Graeme; Millward, Michael J; Nowak, Anna K; Lake, Richard A; Lesterhuis, Willem Joost

Cancer chemotherapy: insights into cellular and tumor microenvironmental mechanisms of action

癌症化疗:深入了解细胞和肿瘤微环境的作用机制

Tilsed, Caitlin M; Fisher, Scott A; Nowak, Anna K; Lake, Richard A; Lesterhuis, W Joost

Malignant Pleural Effusions-A Window Into Local Anti-Tumor T Cell Immunity?

恶性胸腔积液——局部抗肿瘤T细胞免疫的窗口?

Principe, Nicola; Kidman, Joel; Lake, Richard A; Lesterhuis, Willem Joost; Nowak, Anna K; McDonnell, Alison M; Chee, Jonathan

How to Better Understand the Influence of Host Genetics on Developing an Effective Immune Response to Thoracic Cancers

如何更好地了解宿主遗传因素对胸部肿瘤有效免疫反应的影响

Behrouzfar, Kiarash; Burton, Kimberley; Mutsaers, Steve E; Morahan, Grant; Lake, Richard A; Fisher, Scott A