日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SET7/9 exhibits sigmoidal kinetics on nucleosomes, hyperbolic kinetics on histones by an ordered sequential mechanism, and methylates lysine and arginine

SET7/9 在核小体上表现出 S 形动力学,在组蛋白上通过有序的顺序机制表现出双曲线动力学,并能甲基化赖氨酸和精氨酸。

Ige, Olufola O; Hendrickson-Rebizant, Thordur; Luo, Wenxia; Cheung, Phinehas; Lao, Ying; Zahedi, Rene P; Davie, James R; Lakowski, Ted M

Extracellular macrophage migration inhibitory factor (MIF) downregulates adipose hormone-sensitive lipase (HSL) and contributes to obesity

细胞外巨噬细胞移动抑制因子 (MIF) 下调脂肪激素敏感脂肪酶 (HSL) 并导致肥胖

Liujun Chen, Lisha Li, Donghong Cui, Yiheng Huang, Haibin Tong, Haleh Zabihi, Shuxia Wang, Yadan Qi, Ted Lakowski, Lin Leng, Suixin Liu, Hong Wu, Lawrence H Young, Richard Bucala, Dake Qi

Structure, Function, and Activity of Small Molecule and Peptide Inhibitors of Protein Arginine Methyltransferase 1

蛋白质精氨酸甲基转移酶1的小分子和肽类抑制剂的结构、功能和活性

Hendrickson-Rebizant, Thordur; Sudhakar, Sadhana R N; Rowley, Michael J; Frankel, Adam; Davie, James R; Lakowski, Ted M

Protein arginine N-methyltransferase 2 plays a noncatalytic role in the histone methylation activity of PRMT1

蛋白质精氨酸N-甲基转移酶2在PRMT1的组蛋白甲基化活性中发挥非催化作用。

Rowley, Michael J; Prout-Holm, Riley A; Liu, Rui Wen; Hendrickson-Rebizant, Thordur; Ige, Olufola O; Lakowski, Ted M; Frankel, Adam

Bioinformatics driven discovery of small molecule compounds that modulate the FOXM1 and PPARA pathway activities in breast cancer

生物信息学驱动的小分子化合物发现能够调节乳腺癌中FOXM1和PPARA通路活性

Huang, Shujun; Hu, Pingzhao; Lakowski, Ted M

Bioinformatic Analyses of Broad H3K79me2 Domains in Different Leukemia Cell Line Data Sets

不同白血病细胞系数据集中的广泛H3K79me2结构域的生物信息学分析

Sharma, Prerna; Sattarifard, Hedieh; Fatemiyan, Narges; Lakowski, Ted M; Davie, James R

Microtubule modification defects underlie cilium degeneration in cell models of retinitis pigmentosa associated with pre-mRNA splicing factor mutations

微管修饰缺陷是与前 mRNA 剪接因子突变相关的视网膜色素变性细胞模型中纤毛变性的基础

Liliya Nazlamova, Suly Saray Villa Vasquez, Jenny Lord, Varshini Karthik, Man-Kim Cheung, Jörn Lakowski, Gabrielle Wheway

NRL(-/-) gene edited human embryonic stem cells generate rod-deficient retinal organoids enriched in S-cone-like photoreceptors

经NRL(-/-)基因编辑的人类胚胎干细胞可生成富含S锥样感光细胞的视杆细胞缺陷型视网膜类器官

Cuevas, Elisa; Holder, Daniel L; Alshehri, Ashwak H; Tréguier, Julie; Lakowski, Jörn; Sowden, Jane C

Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors

验证钙粘蛋白 HAV6 肽在瞬时调节血脑屏障以治疗脑肿瘤中的作用

Babu V Sajesh, Ngoc H On, Refaat Omar, Samaa Alrushaid, Brian M Kopec, Wei-Guang Wang, Han-Dong Sun, Ryan Lillico, Ted M Lakowski, Teruna J Siahaan, Neal M Davies, Pema-Tenzin Puno, Magimairajan Issai Vanan, Donald W Miller

Absolute Oral Bioavailability of Creatine Monohydrate in Rats: Debunking a Myth

大鼠口服肌酸一水合物的绝对生物利用度:破除一个迷思

Alraddadi, Eman A; Lillico, Ryan; Vennerstrom, Jonathan L; Lakowski, Ted M; Miller, Donald W