日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Evolutionary turnover of key amino acids explains conservation of function without conservation of sequence in transcriptional activation domains

关键氨基酸的进化更替解释了转录激活结构域中功能保守而序列不保守的现象。

LeBlanc, Claire J; Stefani, Jordan; Soriano, Melvin; Lam, Angelica W Y; Zintel, Marissa A; Kotha, Sanjana R; Chase, Emily P; Pimentel-Solorio, Giovani; Vunnum, Aditya; Hu, Gean; Flug, Katherine L; Fultineer, Aaron; Hummel, Niklas; Staller, Max V

Evolutionary discovery and characterization of fungal transcriptional activators using active learning

利用主动学习进行真菌转录激活因子的进化发现和表征

Waldburger, Lucas; Nisonoff, Hunter; Zintel, Marissa; Kirkpatrick, Liam D; Lam, Angelica; Lanclos, Nathan; Keasling, Jay D; Staller, Max V; Shih, Patrick M

Interpretable biophysical neural networks of transcriptional activation domains separate roles of protein abundance and coactivator binding

可解释的转录激活域生物物理神经网络区分了蛋白质丰度和辅激活因子结合的作用

LeBlanc, Claire; Agarwal, Pooja; Demaray, Jack; Hu, Gean; Zintel, Marissa; Lam, Angelica; Castro Hernandez, Joel Enrique; Staller, Max

Evolutionary turnover of key amino acids explains conservation of function without conservation of sequence in transcriptional activation domains.

关键氨基酸的进化更替解释了转录激活结构域中功能保守而序列不保守的原因

LeBlanc Claire, Stefani Jordan, Soriano Melvin, Lam Angelica, Zintel Marissa A, Kotha Sanjana R, Chase Emily, Pimentel-Solorio Giovani, Vunnum Aditya, Flug Katherine, Fultineer Aaron, Hummel Niklas, Staller Max V

Identification of plant transcriptional activation domains

植物转录激活结构域的鉴定

Morffy, Nicholas; Van den Broeck, Lisa; Miller, Caelan; Emenecker, Ryan J; Bryant, John A Jr; Lee, Tyler M; Sageman-Furnas, Katelyn; Wilkinson, Edward G; Pathak, Sunita; Kotha, Sanjana R; Lam, Angelica; Mahatma, Saloni; Pande, Vikram; Waoo, Aman; Wright, R Clay; Holehouse, Alex S; Staller, Max V; Sozzani, Rosangela; Strader, Lucia C

High-content synaptic phenotyping in human cellular models reveals a role for BET proteins in synapse assembly

人类细胞模型中的高含量突触表型揭示了 BET 蛋白在突触组装中的作用

Martin H Berryer, Gizem Rizki, Anna Nathanson, Jenny A Klein, Darina Trendafilova, Sara G Susco, Daisy Lam, Angelica Messana, Kristina M Holton, Kyle W Karhohs, Beth A Cimini, Kathleen Pfaff, Anne E Carpenter, Lee L Rubin, Lindy E Barrett