日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A potent phenylalkylamine disrupts mycobacterial membrane bioenergetics and augments bactericidal activity of bedaquiline.

一种强效的苯烷基胺可破坏分枝杆菌膜生物能量学，并增强贝达喹啉的杀菌活性

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2025.112915
Phua Zheng Yen, Li Ming, Ali Azhar, Cheong Cedric Cheng Sheng, Goh Kai Jie, Seto Marcus Yi Kang, Ng Amos Shi Ying, Sarathy Jickky Palmae, Goh Boon Cher, Go Mei Lin, Chui Wai Keung, Dick Thomas, Lam Yulin
其它
肠道菌群
发表日期：2025
文献求助 收藏

Development of fluorous boronic acid catalysts integrated with sulfur for enhanced amidation efficiency

开发与硫结合的氟硼酸催化剂以提高酰胺化效率

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d3ra03300g
Fridianto, Kevin Timothy; Wen, Ya-Ping; Lo, Lee-Chiang; Lam, Yulin
发表日期：2023
文献求助 收藏

Alkyltriphenylphosphonium turns naphthoquinoneimidazoles into potent membrane depolarizers against mycobacteria

烷基三苯基膦可将萘醌咪唑转化为对抗分枝杆菌的强效膜去极化剂

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d2md00251e
Fridianto, Kevin Timothy; Gunawan, Gregory Adrian; Hards, Kiel; Sarathy, Jickky Palmae; Cook, Gregory M; Dick, Thomas; Go, Mei-Lin; Lam, Yulin
发表日期：2022
文献求助 收藏

Functionalized Dioxonaphthoimidazoliums: A Redox Cycling Chemotype with Potent Bactericidal Activities against Mycobacterium tuberculosis

功能化二氧萘并咪唑鎓：一种具有强效抗结核分枝杆菌杀菌活性的氧化还原循环化学型

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.1c01383
Fridianto, Kevin T; Li, Ming; Hards, Kiel; Negatu, Dereje A; Cook, Gregory M; Dick, Thomas; Lam, Yulin; Go, Mei-Lin
发表日期：2021
文献求助 收藏

Amide-Amine Replacement in Indole-2-carboxamides Yields Potent Mycobactericidal Agents with Improved Water Solubility

吲哚-2-甲酰胺中的酰胺-胺取代可产生具有更高水溶性的强效杀分枝杆菌剂

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.0c00588
Tan, Yu Jia; Li, Ming; Gunawan, Gregory Adrian; Nyantakyi, Samuel Agyei; Dick, Thomas; Go, Mei-Lin; Lam, Yulin
发表日期：2021
文献求助 收藏

Potency Increase of Spiroketal Analogs of Membrane Inserting Indolyl Mannich Base Antimycobacterials Is Due to Acquisition of MmpL3 Inhibition

膜插入吲哚基曼尼希碱抗分枝杆菌药物的螺缩酮类似物效力增强是由于获得了MmpL3抑制作用

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.0c00121
Li, Ming; Phua, Zheng Yen; Xi, Yu; Xu, Zhujun; Nyantakyi, Samuel A; Li, Wei; Jackson, Mary; Wong, Ming Wah; Lam, Yulin; Chng, Shu Sin; Go, Mei Lin; Dick, Thomas
发表日期：2020
文献求助 收藏

In situ imaging and proteome profiling indicate andrographolide is a highly promiscuous compound

原位成像和蛋白质组分析表明，穿心莲内酯是一种具有高度混杂性的化合物。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/srep11522
Li, Lin; Wijaya, Hadhi; Samanta, Sanjay; Lam, Yulin; Yao, Shao Q
发表日期：2015
文献求助 收藏

Sphingosine kinase 1 promotes malignant progression in colon cancer and independently predicts survival of patients with colon cancer by competing risk approach in South asian population

鞘氨醇激酶1促进结肠癌的恶性进展，并且在南亚人群中，通过竞争风险模型独立预测结肠癌患者的生存率。

期刊:Clinical and Translational Gastroenterology
影响因子:3
doi:10.1038/ctg.2013.21
Tan, Sheryl S L; Khin, Lay W; Wong, Lingkai; Yan, Benedict; Ong, Chee W; Datta, Arpita; Salto-Tellez, Manuel; Lam, Yulin; Yap, Celestial T
信号转导
肿瘤
肠癌
肿瘤免疫
发表日期：2014
文献求助 收藏

Oxidation reactions using polymer-supported 2-benzenesulfonyl-3-(4-nitrophenyl)oxaziridine

利用聚合物负载的2-苯磺酰基-3-(4-硝基苯基)氧杂环丙烷进行氧化反应

期刊:Tetrahedron
影响因子:2.2
doi:10.1016/j.tet.2011.08.058
Susanto, Woen; Lam, Yulin
发表日期：2011
文献求助 收藏

CdpA is a Burkholderia pseudomallei cyclic di-GMP phosphodiesterase involved in autoaggregation, flagellum synthesis, motility, biofilm formation, cell invasion, and cytotoxicity

CdpA是类鼻疽伯克霍尔德菌环状二鸟苷酸磷酸二酯酶，参与自聚集、鞭毛合成、运动、生物膜形成、细胞侵袭和细胞毒性。

期刊:Infection and Immunity
影响因子:2.8
doi:10.1128/IAI.00446-09
Lee, Hwee Siang; Gu, Feiyu; Ching, Shi Min; Lam, Yulin; Chua, Kim Lee
微生物学
细胞生物学
毒理研究
发表日期：2010
文献求助 收藏