日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Clostridia from preterm infants metabolize human milk oligosaccharides to suppress pathobionts and modulate intestinal function in organoids

早产儿梭菌代谢人乳寡糖,从而抑制致病菌并调节类器官中的肠道功能。

Chapman, Jonathan A; Masi, Andrea C; Beck, Lauren C; Watson, Hannah; Young, Gregory R; Browne, Hilary P; Shao, Yan; Kiu, Raymond; Nelson, Andrew; Doyle, Jennifer A; Palmowski, Pawel; Lengyel, Márton; Connolly, James P R; Lamb, Christopher A; Porter, Andrew; Lawley, Trevor D; Hall, Lindsay J; Embleton, Nicholas D; Perry, John D; Berrington, Janet E; Stewart, Christopher J

From single-sequences to evolutionary trajectories: protein language models capture the evolutionary potential of SARS-CoV-2

从单序列到进化轨迹:蛋白质语言模型捕捉SARS-CoV-2的进化潜力

Lamb, Kieran D; Hughes, Joseph; Lytras, Spyros; Young, Francesca; Koci, Orges; Herzig, James C; Lovell, Simon C; Grove, Joe; Yuan, Ke; Robertson, David L

Mapping Charge Interactions in Intrinsically Disordered Proteins

绘制固有无序蛋白中的电荷相互作用图谱

Phillips, Michael; Holla, Andrea; Wojtas, Magdalena; Chowdhury, Aritra; Sottini, Andrea; König, Sebastian L B; Mutter, Natalie; Lamb, Nick; Huihui, Jonathan; Lopko, Monika; Soranno, Andrea; Nettels, Daniel; Ożyhar, Andrzej; Schuler, Benjamin; Ghosh, Kingshuk

Next-generation Alzheimer's therapeutics: target assessment and enablement at the Indiana University School of Medicine-Purdue University TREAT-AD Center

下一代阿尔茨海默病疗法:印第安纳大学医学院-普渡大学TREAT-AD中心的靶点评估和开发

Richardson, Timothy I; Klein, Rebecca C; Huang, Kun; Zhang, Jie; Mesecar, Andrew D; Dage, Jeffrey L; Clayton, Brent; Lamb, Bruce T; Palkowitz, Alan D

From consortia discovery to biotech creation: An innovative approach to next-gen Alzheimer's drugs

从联盟发现到生物技术创造:下一代阿尔茨海默病药物的创新方法

Giardina, Sarah F; Culver, Alexander; Ahmed, Chandrama; Mirescu, Christian; Oblak, Adrian L; Brosch, Jared; Clayton, W Brent; Dage, Jeffrey L; Lamb, Bruce T; Richardson, Timothy I; Small, Derek; Palkowitz, Alan D

Generation and characterization of iPSC-derived microglia for in vitro modeling of stimuli-specific neuroimmune responses.

利用 iPSC 衍生的小胶质细胞进行体外模型构建,以模拟刺激特异性神经免疫反应。

Haskell Angela K, Kulas Joshua A, Carter William E, Javens-Wolfe June, Hinkel Raven Dance, Moussaif Mustapha, Smiley Jacob S, Lazaro Olivia, Robertson Sylvia, Palkowitz Alan D, Lamb Bruce T, Richardson Timothy I, Dage Jeffrey L, Chu Shaoyou, Johnson Travis, Stancato Louis F, Syed Abdul Qadir

The association between liver fat content and plasma metabolite profiles in fasting and postprandial states: an integration of a cohort study and a randomized controlled trial

空腹和餐后状态下肝脏脂肪含量与血浆代谢物谱之间的关联:一项队列研究和一项随机对照试验的整合研究

Fang, Yan; de Mutsert, Renée; Gijbels, Anouk; Deng, Keyong; Lamb, Hildo; Rosendaal, Frits R; Mook-Kanamori, Dennis O; van Dijk, Ko Willems; Afman, Lydia A; Li-Gao, Ruifang

Interventions to prevent and treat multiple long-term conditions and their consequences across the life course: concepts and definitions

预防和治疗多种长期疾病及其在生命历程中后果的干预措施:概念和定义

Witham, Miles D; Aithal, Guruprasad P; Collinson, Michelle; Cooper, Rachel; Davies, Melanie J; Farmer, Andrew; Fraser, Simon D S; Hanlon, Peter; Khunti, Kamlesh; Lamb, Sarah E; McDonald, Claire; Nirantharakumar, Krishnarajah; Sayer, Avan A; Shah, Nira; Sheppard, James P; Taylor, Stephanie J C; Yameen, Farheen; Yao, Lily; Singh, Sally J

Smooth Muscle LRRC8A Knockout Preserves Vascular Function in Ang II Hypertension

平滑肌LRRC8A基因敲除可维持血管紧张素II高血压患者的血管功能

Choi, Hyehun; Panja, Sourav; Nguyen, Hong-Ngan; Stark, Ryan J; Lamb, Fred S

Hemoglobin binders reduce inflammation and tissue injury from hemolysis in venovenous extracorporeal circulation.

血红蛋白结合剂可减少静脉-静脉体外循环中溶血引起的炎症和组织损伤。

Govender Krianthan, Lamb Derek R, Walser Cynthia, Pal Saurabh, Setua Saini, O'Boyle Quintin, Pires Ivan S, Lu Shuwei, Irwin David C, Buehler Paul W, Palmer Andre F, Cabrales Pedro