日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of the Phosphonate Flavophos Produced by Burkholderia

伯克霍尔德氏菌产生的膦酸盐黄酮磷的发现

Simon, Max A; Ramos-Figueroa, Josseline S; Lopez, Vanessa Reyes; Ongpipattanakul, Chayanid; Zhu, Lingyang; Giurgiu, Constantin; Hoffpauir, Zoe A; Lamb, Audrey L; Nair, Satish K; van der Donk, Wilfred A

Dual Inhibitors of SARS-CoV-2 3CL Protease and Human Cathepsin L Containing Glutamine Isosteres Are Anti-CoV-2 Agents.

含有谷氨酰胺同分异构体的SARS-CoV-2 3CL蛋白酶和人组织蛋白酶L双重抑制剂是抗CoV-2药物

Kumar Vivek, Zhu Jiyun, Chenna Bala C, Hoffpauir Zoe A, Rademacher Andrew, Rogers Ashley M, Tseng Chien-Te, Drelich Aleksandra, Farzandh Sharfa, Lamb Audrey L, Meek Thomas D

Identification of the phosphatase essential for riboflavin biosynthesis in Aquifex aeolicus

鉴定嗜热栖水菌中核黄素生物合成所必需的磷酸酶

Hoffpauir, Zoe A; Lamb, Audrey L

Evidence for the Chemical Mechanism of RibB (3,4-Dihydroxy-2-butanone 4-phosphate Synthase) of Riboflavin Biosynthesis

核黄素生物合成中 RibB(3,4-二羟基-2-丁酮-4-磷酸合成酶)化学机制的证据

Kenjić, Nikola; Meneely, Kathleen M; Wherritt, Daniel J; Denler, Melissa C; Jackson, Timothy A; Moran, Graham R; Lamb, Audrey L

Substitutions at a rheostat position in human aldolase A cause a shift in the conformational population

人醛缩酶A中变阻器位置的氨基酸替换会导致构象群体的改变

Fenton, Kathryn D; Meneely, Kathleen M; Wu, Tiffany; Martin, Tyler A; Swint-Kruse, Liskin; Fenton, Aron W; Lamb, Audrey L

Rational inhibitor design for Pseudomonas aeruginosa salicylate adenylation enzyme PchD

针对铜绿假单胞菌水杨酸腺苷酸化酶 PchD 的合理抑制剂设计

Shelton, Catherine L; Meneely, Kathleen M; Ronnebaum, Trey A; Chilton, Annemarie S; Riley, Andrew P; Prisinzano, Thomas E; Lamb, Audrey L

Not as easy as π: An insertional residue does not explain the π-helix gain-of-function in two-component FMN reductases

并非像π那样简单:插入残基并不能解释双组分FMN还原酶中π螺旋的功能获得。

McFarlane, Jeffrey S; Hagen, Richard A; Chilton, Annemarie S; Forbes, Dianna L; Lamb, Audrey L; Ellis, Holly R

PvdF of pyoverdin biosynthesis is a structurally unique N(10)-formyltetrahydrofolate-dependent formyltransferase

绿脓菌素生物合成中的 PvdF 是一种结构独特的 N(10)-甲酰四氢叶酸依赖性甲酰转移酶

Kenjić, Nikola; Hoag, Matthew R; Moraski, Garrett C; Caperelli, Carol A; Moran, Graham R; Lamb, Audrey L

Changes in the allosteric site of human liver pyruvate kinase upon activator binding include the breakage of an intersubunit cation-π bond

激活剂结合后,人肝丙酮酸激酶变构位点的变化包括亚基间阳离子-π键的断裂。

McFarlane, Jeffrey S; Ronnebaum, Trey A; Meneely, Kathleen M; Chilton, Annemarie; Fenton, Aron W; Lamb, Audrey L

Unraveling the Structure and Mechanism of the MST(ery) Enzymes

揭示MST(ery)酶的结构和机制

Shelton, Catherine L; Lamb, Audrey L