日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

NEK7 phosphorylation of cortactin modulates the migratory capacity of cells expressing EML4-ALK V3.

NEK7 对 cortactin 的磷酸化调节表达 EML4-ALK V3 的细胞的迁移能力。

Richardson Emily L, Knebel Axel, Straatman Kees R, Gourlay Robert, Lamont Douglas, Hardy Tara, Turnbull Robert E, Robinson Susan W, O'Regan Laura, Bayliss Richard, Fry Andrew M

Multi-omics analysis of SFTS virus infection in Rhipicephalus microplus cells reveals antiviral tick factors.

对微小牛蜱细胞中SFTS病毒感染的多组学分析揭示了抗病毒蜱因子

Petit Marine J, Flory Charlotte, Gu Quan, Fares Mazigh, Lamont Douglas, Score Alan, Davies Kelsey, Bell-Sakyi Lesley, Scaturro Pietro, Brennan Benjamin, Kohl Alain

Phenformin, But Not Metformin, Delays Development of T Cell Acute Lymphoblastic Leukemia/Lymphoma via Cell-Autonomous AMPK Activation

苯乙双胍(而非二甲双胍)通过细胞自主性AMPK激活延缓T细胞急性淋巴细胞白血病/淋巴瘤的发展

Vara-Ciruelos, Diana; Dandapani, Madhumita; Russell, Fiona M; Grzes, Katarzyna M; Atrih, Abdelmadjid; Foretz, Marc; Viollet, Benoit; Lamont, Douglas J; Cantrell, Doreen A; Hardie, D Grahame

The Ancient Drug Salicylate Indirectly Targets Fructose-1,6-Bisphosphatase to Suppress Liver Glucose Production in Diet-Induced Obese Mice.

古代药物水杨酸盐通过间接靶向果糖-1,6-二磷酸酶来抑制饮食诱导肥胖小鼠的肝脏葡萄糖生成

Nisr Raid B, Atrih Abdelmadjid, Lara Erika J Gutierrez, Lamont Douglas, Luda Katarzyna M, McCrimmon Rory J, Sakamoto Kei, Rena Graham, McNeilly Alison D

Uukuniemi virus infection causes a pervasive remodelling of the RNA-binding proteome in tick cells.

乌库涅米病毒感染会导致蜱细胞中 RNA 结合蛋白组发生普遍性重塑

Wilson Alexandra, Kamel Wael, Davies Kelsey, De Laurent Zaydah R, Arif Rozeena, Clarke Andrew T, Bell-Sakyi Lesley, Lamont Douglas, Demyanenko Yana, Noerenberg Marko, Kohl Alain, Mohammed Shabaz, Castello Alfredo, Brennan Benjamin

Glycine-to-aspartic acid mutation at codon 51 in Snca disrupts the synaptic localisation of α-synuclein and enhances its propensity for synucleinopathy.

Snca 基因第 51 位密码子上的甘氨酸突变为天冬氨酸,破坏了 α-突触核蛋白的突触定位,并增强了其发生突触核蛋白病的倾向

West Stephen, Natalwala Ammar, Singh Dolt Karamjit, Lamont Douglas J, McMillan Melanie, Luk Kelvin, Mashimo Tomoji, Kunath Tilo

Alterations in cardiac function correlate with a disruption in fatty acid metabolism in a mouse model of SMA.

SMA小鼠模型中心脏功能的改变与脂肪酸代谢紊乱相关

Nair Nithya N, Kline Rachel A, Boyd Imogen, Anikumar Meenakshi, Thomson Adrian, Lamont Douglas J, Gray Gillian A, Wishart Thomas M, Murray Lyndsay M

Synaptic resilience is associated with maintained cognition during ageing

突触弹性与老年人认知能力的维持有关。

King, Declan; Holt, Kris; Toombs, Jamie; He, Xin; Dando, Owen; Okely, Judith A; Tzioras, Makis; Rose, Jamie; Gunn, Ciaran; Correia, Adele; Montero, Carmen; McAlister, Hannah; Tulloch, Jane; Lamont, Douglas; Taylor, Adele M; Harris, Sarah E; Redmond, Paul; Cox, Simon R; Henstridge, Christopher M; Deary, Ian J; Smith, Colin; Spires-Jones, Tara L

Correction to: Integrative proteomics highlight presynaptic alterations and c-Jun misactivation as convergent pathomechanisms in ALS

更正:整合蛋白质组学揭示突触前改变和c-Jun异常激活是ALS的共同致病机制

Aly, Amr; Laszlo, Zsofia I; Rajkumar, Sandeep; Demir, Tugba; Hindley, Nicole; Lamont, Douglas J; Lehmann, Johannes; Seidel, Mira; Sommer, Daniel; Franz-Wachtel, Mirita; Barletta, Francesca; Heumos, Simon; Czemmel, Stefan; Kabashi, Edor; Ludolph, Albert; Boeckers, Tobias M; Henstridge, Christopher M; Catanese, Alberto

Necroptosis inhibition counteracts neurodegeneration, memory decline, and key hallmarks of aging, promoting brain rejuvenation

抑制坏死性凋亡可以对抗神经退行性变、记忆力衰退和衰老的关键特征,促进大脑再生。

Arrázola, Macarena S; Lira, Matías; Véliz-Valverde, Felipe; Quiroz, Gabriel; Iqbal, Somya; Eaton, Samantha L; Lamont, Douglas J; Huerta, Hernán; Ureta, Gonzalo; Bernales, Sebastián; Cárdenas, J César; Cerpa, Waldo; Wishart, Thomas M; Court, Felipe A