日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

UVA causes dual inactivation of cathepsin B and L underlying lysosomal dysfunction in human dermal fibroblasts.

UVA 会导致组织蛋白酶 B 和 L 的双重失活,从而引起人类真皮成纤维细胞溶酶体功能障碍

Lamore Sarah D, Wondrak Georg T

D-Penicillamine targets metastatic melanoma cells with induction of the unfolded protein response (UPR) and Noxa (PMAIP1)-dependent mitochondrial apoptosis.

D-青霉胺通过诱导未折叠蛋白反应(UPR)和Noxa(PMAIP1)依赖性线粒体凋亡来靶向转移性黑色素瘤细胞

Qiao Shuxi, Cabello Christopher M, Lamore Sarah D, Lesson Jessica L, Wondrak Georg T

Thiostrepton is an inducer of oxidative and proteotoxic stress that impairs viability of human melanoma cells but not primary melanocytes.

硫链丝菌素可诱导氧化应激和蛋白毒性应激,损害人类黑色素瘤细胞的活力,但不损害原代黑色素细胞的活力

Qiao Shuxi, Lamore Sarah D, Cabello Christopher M, Lesson Jessica L, Muñoz-Rodriguez José L, Wondrak Georg T

Autophagic-lysosomal dysregulation downstream of cathepsin B inactivation in human skin fibroblasts exposed to UVA.

UVA照射下人类皮肤成纤维细胞中组织蛋白酶B失活导致自噬溶酶体失调

Lamore Sarah D, Wondrak Georg T

The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosis.

抗疟疾药物双氢青蒿素通过诱导 NOXA 依赖性细胞凋亡,靶向人类转移性黑色素瘤细胞,但不靶向原代黑色素细胞

Cabello Christopher M, Lamore Sarah D, Bair Warner B 3rd, Qiao Shuxi, Azimian Sara, Lesson Jessica L, Wondrak Georg T

Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells

白藜芦醇可阻止芳香烃受体对人乳腺癌细胞中 BRCA-1 的表观遗传沉默

Papoutsis, Andreas J; Lamore, Sarah D; Wondrak, Georg T; Selmin, Ornella I; Romagnolo, Donato F

The malondialdehyde-derived fluorophore DHP-lysine is a potent sensitizer of UVA-induced photooxidative stress in human skin cells

丙二醛衍生的荧光团DHP-赖氨酸是UVA诱导的人类皮肤细胞光氧化应激的有效敏化剂。

Lamore, Sarah D; Azimian, Sara; Horn, David; Anglin, Bobbi L; Uchida, Koji; Cabello, Christopher M; Wondrak, Georg T

Proteomic identification of cathepsin B and nucleophosmin as novel UVA-targets in human skin fibroblasts

蛋白质组学鉴定组织蛋白酶B和核仁磷蛋白为人类皮肤成纤维细胞中新型UVA靶点

Lamore, Sarah D; Qiao, Shuxi; Horn, David; Wondrak, Georg T