Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.
疟疾血红素在免疫学上是惰性的,但它通过将疟疾DNA呈递给Toll样受体9,从而极大地增强先天免疫反应
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.0608745104
Parroche Peggy, Lauw Fanny N, Goutagny Nadege, Latz Eicke, Monks Brian G, Visintin Alberto, Halmen Kristen A, Lamphier Marc, Olivier Martin, Bartholomeu Daniella C, Gazzinelli Ricardo T, Golenbock Douglas T
炎症/感染
疟疾
Toll-Like Receptor