日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Failure of the Anti-Inflammatory Parasitic Worm Product ES-62 to Provide Protection in Mouse Models of Type I Diabetes, Multiple Sclerosis, and Inflammatory Bowel Disease

抗炎寄生虫产品 ES-62 未能为 I 型糖尿病、多发性硬化症和炎症性肠病的小鼠模型提供保护

James Doonan, David Thomas, Michelle H Wong, Hazel J Ramage, Lamyaa Al-Riyami, Felicity E Lumb, Kara S Bell, Karen J Fairlie-Clarke, Colin J Suckling, Kathrin S Michelsen, Hui-Rong Jiang, Anne Cooke, Margaret M Harnett, William Harnett4

The Carbohydrate-linked Phosphorylcholine of the Parasitic Nematode Product ES-62 Modulates Complement Activation

寄生线虫产物 ES-62 的碳水化合物连接磷酰胆碱调节补体活化

Umul Kulthum Ahmed, N Claire Maller, Asif J Iqbal, Lamyaa Al-Riyami, William Harnett, John G Raynes

The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ

蠕虫产品 ES-62 通过诱导 TLR 传感器的选择性自噬溶酶体降解来调节树突状细胞反应,例如 PKCδ

Russell J Eason, Kara S Bell, Fraser A Marshall, David T Rodgers, Miguel A Pineda, Christina N Steiger, Lamyaa Al-Riyami, William Harnett, Margaret M Harnett

The parasitic worm product ES-62 targets myeloid differentiation factor 88-dependent effector mechanisms to suppress antinuclear antibody production and proteinuria in MRL/lpr mice

寄生虫产品 ES-62 靶向髓系分化因子 88 依赖性效应机制,以抑制 MRL/lpr 小鼠的抗核抗体产生和蛋白尿

David T Rodgers, Mairi A McGrath, Miguel A Pineda, Lamyaa Al-Riyami, Justyna Rzepecka, Felicity Lumb, William Harnett, Margaret M Harnett

ES-62 protects against collagen-induced arthritis by resetting interleukin-22 toward resolution of inflammation in the joints

ES-62 通过重置白细胞介素-22,使其向关节炎症消退的方向发展,从而起到预防胶原蛋白诱导性关节炎的作用。

Miguel A Pineda ,David T Rodgers, Lamyaa Al-Riyami, William Harnett, Margaret M Harnett

Designing anti-inflammatory drugs from parasitic worms: a synthetic small molecule analogue of the Acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis

从寄生虫中设计抗炎药物:棘唇虫产品 ES-62 的合成小分子类似物可防止胶原诱导性关节炎的发展

Lamyaa Al-Riyami, Miguel A Pineda, Justyna Rzepecka, Judith K Huggan, Abedawn I Khalaf, Colin J Suckling, Fraser J Scott, David T Rodgers, Margaret M Harnett, William Harnett

Mast Cell Subsets and Their Functional Modulation by the Acanthocheilonema viteae Product ES-62

肥大细胞亚群及其由棘唇藻产物 ES-62 进行的功能调节

Dimity H Ball, Hwee Kee Tay, Kara S Bell, Michelle L Coates, Lamyaa Al-Riyami, Justyna Rzepecka, William Harnett, Margaret M Harnett