日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Stalling the Enemy: Targeting Nsp13 for Next-Generation SARS-CoV-2 Antivirals

阻击敌人:以 Nsp13 为靶点开发下一代 SARS-CoV-2 抗病毒药物

Castro, Jose M; Slack, Ryan L; Ong, Yee T; Zhang, Huanchun; Gifford, Levi B; Courouble, Valentine V; Aiken, Riley M; Shankar, Vishal; O'Leary, Timothy R; Griffin, Patrick R; Lan, Shuiyun; Du, Yuhong; Fu, Haian; Sarafianos, Stefan G

Strategy to overcome a nirmatrelvir resistance mechanism in the SARS-CoV-2 nsp5 protease

克服SARS-CoV-2 nsp5蛋白酶中尼尔马特雷韦耐药机制的策略

Neilsen, Grace; Lan, Shuiyun; Slack, Ryan L; Lorson, Zachary C; Emanuelli Castaner, Andres; Lee, Rachel; Edwards, Kristin G; Zhang, Huanchun; Lee, Jasper; Cantara, William A; Cilento, Maria E; Zhang, Hongwang; De, Ramyani; Amblard, Franck; Tedbury, Philip R; Kirby, Karen A; Schinazi, Raymond F; Sarafianos, Stefan G

Synthesis and Antiviral Evaluation of Unexplored Dioxolane-Derived 7‑Deazapurine Nucleoside Analogues against Epstein-Barr Virus (EBV)

合成及未探索的二氧戊环衍生的7-脱氮嘌呤核苷类似物抗Epstein-Barr病毒(EBV)的抗病毒活性评价

Singh, Uma S; Jones, Ransom A; Kothapalli, Yugandhar; Lan, Shuiyun; Zhang, Xing-Quan; Slack, Ryan L; Thoomu, Harischandra P; Schooley, Robert T; Sarafianos, Stefan G; Chu, Chung K

Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease.

冠状病毒3C样蛋白酶新型肽模拟抑制剂的合成及生物学评价

Amblard Franck, LeCher Julia C, De Ramyani, Zhou Shaoman, Liu Peng, Goh Shu Ling, Tao Sijia, Patel Dharmeshkumar, Downs-Bowen Jessica, Zandi Keivan, Zhang Huanchun, Chaudhry Gitika, McBrayer Tamara, Muczynski Michael, Al-Homoudi Abdullah, Engel Joseph, Lan Shuiyun, Sarafianos Stefan G, Kovari Ladislau C, Schinazi Raymond F

Dimming the corona: studying SARS-coronavirus-2 at reduced biocontainment level using replicons and virus-like particles

降低冠状病毒的传播风险:利用复制子和病毒样颗粒在较低的生物安全等级下研究SARS冠状病毒2

Neilsen, Grace; Mathew, Asha Maria; Castro, Jose M; McFadden, William M; Wen, Xin; Ong, Yee T; Tedbury, Philip R; Lan, Shuiyun; Sarafianos, Stefan G

Virulent infection of outbred Hartley guinea pigs with recombinant Pichinde virus as a surrogate small animal model for human Lassa fever

用重组皮钦德病毒对非近交系哈特利豚鼠进行强毒性感染,以此作为人类拉沙热的替代小动物模型。

Lan, Shuiyun; Shieh, Wun-Ju; Huang, Qinfeng; Zaki, Sherif R; Liang, Yuying; Ly, Hinh

Pichinde Virus Infection of Outbred Hartley Guinea Pigs as a Surrogate Animal Model for Human Lassa Fever: Histopathological and Immunohistochemical Analyses

皮钦德病毒感染哈特利豚鼠作为人类拉沙热的替代动物模型:组织病理学和免疫组织化学分析

Shieh, Wun-Ju; Lan, Shuiyun; Zaki, Sherif R; Ly, Hinh; Liang, Yuying

Establishment of Bisegmented and Trisegmented Reverse Genetics Systems to Generate Recombinant Pichindé Viruses

建立双节段和三节段反向遗传学系统以产生重组皮钦德病毒

Dhanwani, Rekha; Huang, Qinfeng; Lan, Shuiyun; Zhou, Yanqing; Shao, Junjie; Liang, Yuying; Ly, Hinh

In vitro and in vivo characterizations of pichinde viral nucleoprotein exoribonuclease functions

皮钦德病毒核蛋白外切核糖核酸酶功能的体外和体内表征

Huang, Qinfeng; Shao, Junjie; Lan, Shuiyun; Zhou, Yanqin; Xing, Junji; Dong, Changjiang; Liang, Yuying; Ly, Hinh

Cap binding and immune evasion revealed by Lassa nucleoprotein structure

拉沙病毒核蛋白结构揭示帽结合和免疫逃避机制

Qi, Xiaoxuan; Lan, Shuiyun; Wang, Wenjian; Schelde, Lisa McLay; Dong, Haohao; Wallat, Gregor D; Ly, Hinh; Liang, Yuying; Dong, Changjiang