日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Antibacterial activity of ibezapolstat against antimicrobial-resistant clinical strains of Clostridioides difficile

伊贝扎波尔司他针对耐药性艰难梭菌临床菌株的抗菌活性

Bassères, Eugénie; Eubank, Taryn A; Begum, Khurshida; Alam, M Jahangir; Jo, Jinhee; Le, Thanh M; Lancaster, Chris K; Gonzales-Luna, Anne J; Garey, Kevin W

Efficacy, Safety, Pharmacokinetics, and Microbiome Changes of Ibezapolstat in Adults with Clostridioides difficile Infection: A Phase 2a Multicenter Clinical Trial

伊贝扎泊司他治疗成人艰难梭菌感染的疗效、安全性、药代动力学和微生物组变化:一项 2a 期多中心临床试验

Garey, Kevin W; McPherson, Jacob; Dinh, An Q; Hu, Chenlin; Jo, Jinhee; Wang, Weiqun; Lancaster, Chris K; Gonzales-Luna, Anne J; Loveall, Caroline; Begum, Khurshida; Jahangir Alam, M; Silverman, Michael H; Hanson, Blake M

Functional and Metagenomic Evaluation of Ibezapolstat for Early Evaluation of Anti-Recurrence Effects in Clostridioides difficile Infection

伊贝扎泊司他用于早期评估其在艰难梭菌感染中抗复发作用的功能和宏基因组学评价

McPherson, Jacob; Hu, Chenlin; Begum, Khurshida; Wang, Weiqun; Lancaster, Chris; Gonzales-Luna, Anne J; Loveall, Caroline; Silverman, Michael H; Alam, M Jahangir; Garey, Kevin W

Multi-country surveillance of Clostridioides difficile demonstrates high prevalence of spores in non-healthcare environmental settings

针对艰难梭菌的多国监测表明,在非医疗机构环境中,艰难梭菌孢子的检出率很高。

Jo, Jinhee; Gonzales-Luna, Anne J; Lancaster, Chris K; McPherson, Jacob K; Begum, Khurshida; Jahangir Alam, M; Garey, Kevin W

Systems biology evaluation of refractory Clostridioides difficile infection including multiple failures of fecal microbiota transplantation

系统生物学评估难治性艰难梭菌感染,包括多次粪便微生物移植失败

Gonzales-Luna, Anne J; Spinler, Jennifer K; Oezguen, Numan; Khan, Md Abdul Wadud; Danhof, Heather A; Endres, Bradley T; Alam, M Jahangir; Begum, Khurshida; Lancaster, Chris; Costa, Gabriela Pd; Savidge, Tor C; Hurdle, Julian G; Britton, Robert; Garey, Kevin W

PCR ribotypes of Clostridioides difficile across Texas from 2011 to 2018 including emergence of ribotype 255

2011年至2018年德克萨斯州艰难梭菌PCR核糖体分型,包括255型核糖体分型的出现

Gonzales-Luna, Anne J; Carlson, Travis J; Dotson, Kierra M; Poblete, Kelley; Costa, Gabriela; Miranda, Julie; Lancaster, Chris; Walk, Seth T; Tupy, Shawn; Begum, Khurshida; Alam, M Jahangir; Garey, Kevin W

In Vitro Activity of Omadacycline, a New Tetracycline Analog, and Comparators against Clostridioides difficile

奥马环素(一种新型四环素类似物)及其对照药物对艰难梭菌的体外活性

Begum, Khurshida; Bassères, Eugénie; Miranda, Julie; Lancaster, Chris; Gonzales-Luna, Anne J; Carlson, Travis J; Rashid, Tasnuva; Eyre, David W; Wilcox, Mark H; Alam, M Jahangir; Garey, Kevin W

Eosinopenia and Binary Toxin Increase Mortality in Hospitalized Patients With Clostridioides difficile Infection

嗜酸性粒细胞减少症和二元毒素会增加艰难梭菌感染住院患者的死亡率

Carlson, Travis J; Endres, Bradley T; Le Pham, Julie; Gonzales-Luna, Anne J; Alnezary, Faris S; Nebo, Kimberly; Miranda, Julie; Lancaster, Chris; Bassères, Eugénie; Begum, Khurshida; Alam, M Jahangir; Reveles, Kelly R; Garey, Kevin W

A randomized, double-blind, placebo-controlled, single and multiple ascending dose Phase 1 study to determine the safety, pharmacokinetics and food and faecal microbiome effects of ibezapolstat administered orally to healthy subjects

一项随机、双盲、安慰剂对照、单次和多次递增剂量的 I 期研究,旨在确定口服 ibezapolstat 对健康受试者的安全性、药代动力学以及对食物和粪便微生物组的影响。

Garey, Kevin W; Begum, Khurshida; Lancaster, Chris; Gonzales-Luna, Anne; Bui, Dinh; Mercier, Julie; Seng Yue, Corinne; Ducharme, Murray P; Hu, Ming; Vince, Bradley; Silverman, Michael H; Alam, M Jahangir; Kankam, Martin

Molecular epidemiology of toxigenic Clostridioides difficile isolates from hospitalized patients and the hospital environment in Dhaka, Bangladesh

孟加拉国达卡住院患者及医院环境中产毒性艰难梭菌分离株的分子流行病学研究

Sofjan, Amelia K; Islam, Mohammad Aminul; Halder, Kakali; Kabir, Nayel D; Saleh, Ahmed Abu; Miranda, Julie; Lancaster, Chris; Begum, Khurshida; Alam, M Jahangir; Garey, Kevin W