日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The chromatin remodeller CHD4 regulates transcription factor binding to both prevent activation of silent enhancers and maintain active regulatory elements.

染色质重塑因子 CHD4 调节转录因子结合,既能防止沉默增强子的激活,又能维持活性调控元件。

Koulle Andria, Ogundele Oluwaseun, Shah Devina, Baker India, Lopez Maya, Lando David, Reynolds Nicola, Ragheb Ramy, Laue Ernest D, Hendrich Brian

Enhancer-promoter interactions are reconfigured through the formation of long-range multiway hubs as mouse ES cells exit pluripotency.

当小鼠胚胎干细胞退出多能性时,增强子-启动子相互作用通过形成长程多向枢纽而重新配置

Lando David, Ma Xiaoyan, Cao Yang, Jartseva Aleksandra, Stevens Tim J, Boucher Wayne, Reynolds Nicola, Montibus Bertille, Hall Dominic, Lackner Andreas, Ragheb Ramy, Leeb Martin, Hendrich Brian D, Laue Ernest D

3D structures of individual mammalian genomes studied by single-cell Hi-C

利用单细胞Hi-C技术研究哺乳动物单个基因组的三维结构。

Stevens, Tim J; Lando, David; Basu, Srinjan; Atkinson, Liam P; Cao, Yang; Lee, Steven F; Leeb, Martin; Wohlfahrt, Kai J; Boucher, Wayne; O'Shaughnessy-Kirwan, Aoife; Cramard, Julie; Faure, Andre J; Ralser, Meryem; Blanco, Enrique; Morey, Lluis; Sansó, Miriam; Palayret, Matthieu G S; Lehner, Ben; Di Croce, Luciano; Wutz, Anton; Hendrich, Brian; Klenerman, Dave; Laue, Ernest D

Virtual-'light-sheet' single-molecule localisation microscopy enables quantitative optical sectioning for super-resolution imaging.

虚拟“光片”单分子定位显微镜可实现超分辨率成像的定量光学切片

Palayret Matthieu, Armes Helen, Basu Srinjan, Watson Adam T, Herbert Alex, Lando David, Etheridge Thomas J, Endesfelder Ulrike, Heilemann Mike, Laue Ernest, Carr Antony M, Klenerman David, Lee Steven F

Quantification of DNA-associated proteins inside eukaryotic cells using single-molecule localization microscopy

利用单分子定位显微镜对真核细胞内DNA相关蛋白进行定量分析

Etheridge, Thomas J; Boulineau, Rémi L; Herbert, Alex; Watson, Adam T; Daigaku, Yasukazu; Tucker, Jem; George, Sophie; Jönsson, Peter; Palayret, Matthieu; Lando, David; Laue, Ernest; Osborne, Mark A; Klenerman, David; Lee, Steven F; Carr, Antony M

A microfluidic device for the hydrodynamic immobilisation of living fission yeast cells for super-resolution imaging

一种用于超分辨率成像的活体裂殖酵母细胞流体动力学固定的微流控装置

Bell, Laurence; Seshia, Ashwin; Lando, David; Laue, Ernest; Palayret, Matthieu; Lee, Steven F; Klenerman, David

Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast.

定量单分子显微镜显示,CENP-A(Cnp1) 沉积发生在裂殖酵母的 G2 期

Lando David, Endesfelder Ulrike, Berger Harald, Subramanian Lakxmi, Dunne Paul D, McColl James, Klenerman David, Carr Antony M, Sauer Markus, Allshire Robin C, Heilemann Mike, Laue Ernest D

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

FIH-1 是一种天冬酰胺羟化酶,可调节缺氧诱导因子的转录活性。

Lando, David; Peet, Daniel J; Gorman, Jeffrey J; Whelan, Dean A; Whitelaw, Murray L; Bruick, Richard K

On Separate Acromion Process Simulating Fracture

模拟骨折的独立肩峰突

Lando, David; Stevens, Tim J; Basu, Srinjan; Laue, Ernest D; Struthers, John