日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Inhibition of tau neuronal internalization using anti-tau single domain antibodies

利用抗tau单域抗体抑制tau蛋白神经元内吞作用

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-58383-4
Danis, Clément; Dupré, Elian; Bouillet, Thomas; Denéchaud, Marine; Lefebvre, Camille; Nguyen, Marine; Mortelecque, Justine; Cantrelle, François-Xavier; Rain, Jean-Christophe; Hanoulle, Xavier; Colin, Morvane; Buée, Luc; Landrieu, Isabelle
神经科学
发表日期：2025
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Anti-tau VHH therapy against PHF6: a safe approach to slowing the phenotype of tau pathology

针对PHF6的抗tau蛋白VHH疗法：一种减缓tau蛋白病理表型进展的安全方法

期刊:Alzheimers Research & Therapy
影响因子:7.9
doi:10.1186/s13195-025-01823-6
Raphaelle Caillierez ,Clémence Leboullenger ,Sarah Leclercq ,Mélanie Besegher ,Séverine Bégard ,Florent Auger ,Claude-Alain Maurage ,Bertrand Accart ,Justine Mortelecque ,Elian Dupré ,Clément Danis ,Isabelle Landrieu # ,Luc Buée # ,Morvane Colin #
PHF6
发表日期：2025
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Effect of PHF-1 hyperphosphorylation on the seeding activity of C-terminal Tau fragments.

PHF-1 过度磷酸化对 C 端 Tau 片段种子活性的影响

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-91867-3
El Hajjar Léa, Boll Emmanuelle, Cantrelle François-Xavier, Bridot Clarisse, Landrieu Isabelle, Smet-Nocca Caroline
其它
磷酸化
发表日期：2025
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Precision proteoform design for 4R tau isoform selective templated aggregation

针对 4R tau 亚型选择性模板聚集的精确蛋白质组设计

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2320456121
Longhini, Andrew P; DuBose, Austin; Lobo, Samuel; Vijayan, Vishnu; Bai, Yeran; Rivera, Erica Keane; Sala-Jarque, Julia; Nikitina, Arina; Carrettiero, Daniel C; Unger, Matthew T; Sclafani, Olivia R; Fu, Valerie; Beckett, Emily R; Vigers, Michael; Buée, Luc; Landrieu, Isabelle; Shell, Scott; Shea, Joan E; Han, Songi; Kosik, Kenneth S
发表日期：2024
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Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models

塑造阿尔茨海默病疾病修饰药物临床前开发的未来：tau蛋白传播模型的系统性综述

期刊:Acta Neuropathologica Communications
影响因子:5.7
doi:10.1186/s40478-024-01748-5
Basheer, Neha; Buee, Luc; Brion, Jean-Pierre; Smolek, Tomas; Muhammadi, Muhammad Khalid; Hritz, Jozef; Hromadka, Tomas; Dewachter, Ilse; Wegmann, Susanne; Landrieu, Isabelle; Novak, Petr; Mudher, Amritpal; Zilka, Norbert
阿尔茨海默症
发表日期：2024
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A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein

针对tau内在无序蛋白中PHF6线性肽的单域抗体的选择和优化策略

期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1016/j.jbc.2024.107163
Justine Mortelecque, Orgeta Zejneli, Séverine Bégard, Margarida C Simões, Lea ElHajjar, Marine Nguyen, François-Xavier Cantrelle, Xavier Hanoulle, Jean-Christophe Rain, Morvane Colin, Cláudio M Gomes, Luc Buée, Isabelle Landrieu, Clément Danis, Elian Dupré
PHF6
发表日期：2024
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The role of writing motives in the interplay between implicit theories, achievement goals, self-efficacy, and writing performance

写作动机在内隐理论、成就目标、自我效能感和写作表现之间的相互作用中所起的作用

期刊:Frontiers in Psychology
影响因子:2.9
doi:10.3389/fpsyg.2023.1149923
De Smedt, Fien; Landrieu, Yana; De Wever, Bram; Van Keer, Hilde
发表日期：2023
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Argumentation in collaboration: the impact of explicit instruction and collaborative writing on secondary school students' argumentative writing

合作论证：显性指导和合作写作对中学生论证写作的影响

期刊:
影响因子:
doi:10.1007/s11145-023-10439-x
Landrieu, Yana; De Smedt, Fien; Van Keer, Hilde; De Wever, Bram
发表日期：2023
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Precision Proteoform Design for 4R Tau Isoform Selective Templated Aggregation

4R Tau 亚型选择性模板聚集的精确蛋白质组设计

期刊:
影响因子:
doi:10.1101/2023.08.31.555649
Longhini, Andrew P; DuBose, Austin; Lobo, Samuel; Vijayan, Vishnu; Bai, Yeran; Rivera, Erica Keane; Sala-Jarque, Julia; Nikitina, Arina; Carrettiero, Daniel C; Unger, Matthew; Sclafani, Olivia; Fu, Valerie; Vigers, Michael; Buee, Luc; Landrieu, Isabelle; Shell, Scott; Shea, Joan E; Han, Songi; Kosik, Kenneth S
发表日期：2023
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Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment

通过使用单域抗体片段靶向神经元内的 Tau 成核核心来抑制 Tau 的播种

期刊:Molecular Therapy
影响因子:12.1
doi:10.1016/j.ymthe.2022.01.009
Clément Danis, Elian Dupré, Orgeta Zejneli, Raphaëlle Caillierez, Alexis Arrial, Séverine Bégard, Justine Mortelecque, Sabiha Eddarkaoui, Anne Loyens, François-Xavier Cantrelle, Xavier Hanoulle, Jean-Christophe Rain, Morvane Colin, Luc Buée, Isabelle Landrieu
神经
Tau
发表日期：2022
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