日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Activation of FoxO1 prevents and reverses cardiac hypertrophy from diverse stimuli

FoxO1的激活可以预防和逆转由多种刺激引起的心肌肥大。

Martin, Thomas G; Langer, Stephen J; Crocini, Claudia; Chung, Eunhee; Leinwand, Leslie A

Regression of postprandial cardiac hypertrophy in burmese pythons is mediated by FoxO1

缅甸蟒餐后心脏肥大的消退是由FoxO1介导的。

Martin, Thomas G; Hunt, Dakota R; Langer, Stephen J; Tan, Yuxiao; Ebmeier, Christopher C; Leinwand, Leslie A

A Conserved Mechanism of Cardiac Hypertrophy Regression through FoxO1.

FoxO1介导的保守性心脏肥大消退机制

Martin Thomas G, Hunt Dakota R, Langer Stephen J, Tan Yuxiao, Ebmeier Christopher C, Crocini Claudia, Chung Eunhee, Leinwand Leslie A

Divergent Molecular Phenotypes in Point Mutations at the Same Residue in Beta-Myosin Heavy Chain Lead to Distinct Cardiomyopathies

β-肌球蛋白重链同一残基上的点突变导致不同的分子表型,进而引发不同的心肌病

Lehman, Sarah J; Meller, Artur; Solieva, Shahlo O; Lotthammer, Jeffrey M; Greenberg, Lina; Langer, Stephen J; Greenberg, Michael J; Tardiff, Jil C; Bowman, Gregory R; Leinwand, Leslie

Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties

携带与早发性或晚发性肥厚型心肌病相关的突变的肌球蛋白运动结构域具有相似的特性。

Vera, Carlos D; Johnson, Chloe A; Walklate, Jonathan; Adhikari, Arjun; Svicevic, Marina; Mijailovich, Srboljub M; Combs, Ariana C; Langer, Stephen J; Ruppel, Kathleen M; Spudich, James A; Geeves, Michael A; Leinwand, Leslie A

Particulate matter, endotoxin, and worker respiratory health on large Californian dairies

加州大型奶牛场的颗粒物、内毒素和工人呼吸健康

Diane C Mitchell, Tracey L Armitage, Marc B Schenker, Deborah H Bennett, Daniel J Tancredi, Chelsea Eastman Langer, Stephen J Reynolds, Greg Dooley, John Mehaffy, Frank M Mitloehner

Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway

水凝胶通过弹性调控的PI3K/AKT通路维持瓣膜成纤维细胞的天然表型。

Wang, Huan; Tibbitt, Mark W; Langer, Stephen J; Leinwand, Leslie A; Anseth, Kristi S

Immunogenicity of intrathecal plasmid gene delivery: cytokine release and effects on transgene expression

鞘内质粒基因递送的免疫原性:细胞因子释放及其对转基因表达的影响

Hughes, Travis S; Langer, Stephen J; Virtanen, Salla I; Chavez, Raymond A; Watkins, Linda R; Milligan, Erin D; Leinwand, Leslie A

Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats

鞘内注射白细胞介素-10基因疗法可减轻紫杉醇诱导的大鼠背根神经节机械性痛觉过敏和促炎细胞因子表达

Ledeboer, Annemarie; Jekich, Brian M; Sloane, Evan M; Mahoney, John H; Langer, Stephen J; Milligan, Erin D; Martin, David; Maier, Steven F; Johnson, Kirk W; Leinwand, Leslie A; Chavez, Raymond A; Watkins, Linda R

Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain.

鞘内注射聚合物基白细胞介素-10基因治疗神经性疼痛

Milligan Erin D, Soderquist Ryan G, Malone Stephanie M, Mahoney John H, Hughes Travis S, Langer Stephen J, Sloane Evan M, Maier Steven F, Leinwand Leslie A, Watkins Linda R, Mahoney Melissa J