日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Molecular characterisation of the trafficking rescue of defective ABCB4 variants by roscovitine analogues

罗斯科维汀类似物对缺陷型ABCB4变体转运拯救作用的分子特征

Banet, Manon; Crespi, Veronica; Elie, Jonathan; Riahi, Yosra; Lakli, Mounia; Mareux, Elodie; Gonzales, Emmanuel; Jacquemin, Emmanuel; Meijer, Laurent; Lapalus, Martine; Di Meo, Florent; Falguières, Thomas

Correction of a Traffic-Defective Missense ABCB11 Variant Responsible for Progressive Familial Intrahepatic Cholestasis Type 2.

纠正导致进行性家族性肝内胆汁淤积症 2 型的交通缺陷错义 ABCB11 变异

Lapalus Martine, Mareux Elodie, Amzal Rachida, Drège Emmanuelle, Riahi Yosra, Petit Sylvain, Banet Manon, Falguières Thomas, Callebaut Isabelle, Figadère Bruno, Joseph Delphine, Gonzales Emmanuel, Jacquemin Emmanuel

Identification of new correctors for traffic-defective ABCB4 variants by a high-content screening approach

利用高内涵筛选方法鉴定针对交通缺陷型ABCB4变体的新型校正因子

Lakli, Mounia; Dumont, Julie; Vauthier, Virginie; Charton, Julie; Crespi, Veronica; Banet, Manon; Riahi, Yosra; Ben Saad, Amel; Mareux, Elodie; Lapalus, Martine; Gonzales, Emmanuel; Jacquemin, Emmanuel; Di Meo, Florent; Deprez, Benoit; Leroux, Florence; Falguières, Thomas

Outcomes of 38 patients with PFIC3: Impact of genotype and of response to ursodeoxycholic acid therapy

38例PFIC3患者的预后:基因型和熊去氧胆酸治疗反应的影响

Gonzales, Emmanuel; Gardin, Antoine; Almes, Marion; Darmellah-Remil, Amaria; Seguin, Hanh; Mussini, Charlotte; Franchi-Abella, Stéphanie; Duché, Mathieu; Ackermann, Oanez; Thébaut, Alice; Habes, Dalila; Hermeziu, Bogdan; Lapalus, Martine; Falguières, Thomas; Combal, Jean-Philippe; Benichou, Bernard; Valero, Sonia; Davit-Spraul, Anne; Jacquemin, Emmanuel

Seasonality and growth in tropical freshwater ectotherm vertebrates: Results from 1-year experimentation in the African gray bichir, giraffe catfish, and the West African mud turtle

热带淡水变温脊椎动物的季节性和生长:以非洲灰多鳍鱼、长颈鲶和西非泥龟为对象,为期一年的实验结果。

Gardin, Axelle; Otero, Olga; Réveillac, Elodie; Lafitte, Alexandra; Valentin, Xavier; Lapalus, Florian; Bouchon, Didier; Garcia, Géraldine

In Vitro Rescue of the Bile Acid Transport Function of ABCB11 Variants by CFTR Potentiators

CFTR 增效剂体外挽救 ABCB11 变体的胆汁酸转运功能

Elodie Mareux, Martine Lapalus, Amel Ben Saad, Renaud Zelli, Mounia Lakli, Yosra Riahi, Marion Almes, Manon Banet, Isabelle Callebaut, Jean-Luc Decout, Thomas Falguières, Emmanuel Jacquemin, Emmanuel Gonzales

In vitro functional rescue by ivacaftor of an ABCB11 variant involved in PFIC2 and intrahepatic cholestasis of pregnancy

体外实验表明,ivacaftor 可挽救与 PFIC2 和妊娠期肝内胆汁淤积症相关的 ABCB11 变异体的功能。

Mareux, Elodie; Lapalus, Martine; Ben-Saad, Amel; Callebaut, Isabelle; Falguières, Thomas; Gonzales, Emmanuel; Jacquemin, Emmanuel

RAB10 Interacts with ABCB4 and Regulates Its Intracellular Traffic

RAB10 与 ABCB4 相互作用并调节其细胞内运输

Amel Ben Saad, Virginie Vauthier, Martine Lapalus, Elodie Mareux, Evangéline Bennana, Anne-Marie Durand-Schneider, Alix Bruneau, Jean-Louis Delaunay, Emmanuel Gonzales, Chantal Housset, Tounsia Aït-Slimane, François Guillonneau, Emmanuel Jacquemin, Thomas Falguières

A Model-Based Illustrative Exploratory Approach to Optimize the Dosing of Peg-IFN/RBV in Cirrhotic Hepatitis C Patients Treated With Triple Therapy

基于模型的探索性方法,用于优化接受三联疗法治疗的肝硬化丙型肝炎患者中聚乙二醇干扰素/利巴韦林的剂量。

Laouénan, C; Guedj, J; Peytavin, G; Nguyen, Th Tram; Lapalus, M; Khelifa-Mouri, F; Boyer, N; Zoulim, F; Serfaty, L; Bronowicki, J-P; Martinot-Peignoux, M; Lada, O; Asselah, T; Dorival, C; Hézode, C; Carrat, F; Nicot, F; Marcellin, P; Mentré, F

Using pharmacokinetic and viral kinetic modeling to estimate the antiviral effectiveness of telaprevir, boceprevir, and pegylated interferon during triple therapy in treatment-experienced hepatitis C virus-infected cirrhotic patients

利用药代动力学和病毒动力学模型评估特拉匹韦、博赛匹韦和聚乙二醇干扰素三联疗法对既往接受过治疗的丙型肝炎病毒感染肝硬化患者的抗病毒疗效

Laouénan, Cédric; Marcellin, Patrick; Lapalus, Martine; Khelifa-Mouri, Feryel; Boyer, Nathalie; Zoulim, Fabien; Serfaty, Lawrence; Bronowicki, Jean-Pierre; Martinot-Peignoux, Michelle; Lada, Olivier; Asselah, Tarik; Dorival, Céline; Hézode, Christophe; Carrat, Fabrice; Nicot, Florence; Peytavin, Gilles; Mentré, France; Guedj, Jeremie