A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.
RNF186 中的蛋白质截短变体 R179X 可预防溃疡性结肠炎
期刊:Nature Communications
影响因子:15.7
doi:10.1038/ncomms12342
Rivas Manuel A, Graham Daniel, Sulem Patrick, Stevens Christine, Desch A Nicole, Goyette Philippe, Gudbjartsson Daniel, Jonsdottir Ingileif, Thorsteinsdottir Unnur, Degenhardt Frauke, Mucha Sören, Kurki Mitja I, Li Dalin, D'Amato Mauro, Annese Vito, Vermeire Severine, Weersma Rinse K, Halfvarson Jonas, Paavola-Sakki Paulina, Lappalainen Maarit, Lek Monkol, Cummings Beryl, Tukiainen Taru, Haritunians Talin, Halme Leena, Koskinen Lotta L E, Ananthakrishnan Ashwin N, Luo Yang, Heap Graham A, Visschedijk Marijn C, MacArthur Daniel G, Neale Benjamin M, Ahmad Tariq, Anderson Carl A, Brant Steven R, Duerr Richard H, Silverberg Mark S, Cho Judy H, Palotie Aarno, Saavalainen Päivi, Kontula Kimmo, Färkkilä Martti, McGovern Dermot P B, Franke Andre, Stefansson Kari, Rioux John D, Xavier Ramnik J, Daly Mark J, Barrett J, de Lane K, Edwards C, Hart A, Hawkey C, Jostins L, Kennedy N, Lamb C, Lee J, Lees C, Mansfield J, Mathew C, Mowatt C, Newman B, Nimmo E, Parkes M, Pollard M, Prescott N, Randall J, Rice D, Satsangi J, Simmons A, Tremelling M, Uhlig H, Wilson D, Abraham C, Achkar J P, Bitton A, Boucher G, Croitoru K, Fleshner P, Glas J, Kugathasan S, Limbergen J V, Milgrom R, Proctor D, Regueiro M, Schumm P L, Sharma Y, Stempak J M, Targan S R, Wang M H
