日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Phase 1/1B Trial of Pembrolizumab and Trametinib in Advanced NSCLC Enriched for KRAS Mutations.

帕博利珠单抗和曲美替尼治疗富含 KRAS 突变的晚期非小细胞肺癌的 1/1B 期试验

Riess Jonathan W, Lara Matthew S, Luxardi Guillaume, Lopez de Rodas Miguel, Shimoda Michiko, Kelly Karen, Lara Primo N, Beckett Laurel, Monjazeb Arta, Schalper Kurt A, Maverakis Emanual, Gandara David R

POLE Mutation Associated With Microsatellite Instability and High Tumor Mutational Burden Confers Exquisite Sensitivity to Immune Checkpoint Inhibitor Therapy in Non-Small Cell Lung Cancer: A Case Report and Genomic Database Analysis

POLE基因突变与微卫星不稳定性及高肿瘤突变负荷相关,赋予非小细胞肺癌对免疫检查点抑制剂治疗的极高敏感性:病例报告及基因组数据库分析

Lara, Matthew S; Riess, Jonathan W; Kaleka, Guneet; Borowsky, Alexander; McPherson, John D; Godoy, Luis A; Grego, Lorenzo; Lara, Primo N Jr; Mitsiades, Nicholas

Immune Cell Dynamics in EGFR-Mutated NSCLC Treated With Afatinib and Pembrolizumab: Results From a Phase IB Study

阿法替尼和帕博利珠单抗治疗EGFR突变型非小细胞肺癌的免疫细胞动力学:一项IB期研究的结果

Riess, Jonathan W; Lara, Matthew S; Lopez de Rodas, Miguel; Luxardi, Guillaume; Herbert, Samantha; Shimoda, Michiko; Kelly, Karen; Meerlev, Alexander; Moore, Elizabeth; Beckett, Laurel; Monjazeb, Arta; Schalper, Kurt; Maverakis, Emanual; Gandara, David R

Current Trial Report: A Multicenter Phase I/Ib study of Capmatinib Plus Trametinib in Patients With Metastatic Nonsmall Cell Lung Center Harboring MET Exon 14 Skipping Mutations and Other MET-Alterations

当前试验报告:一项针对携带MET外显子14跳跃突变和其他MET改变的转移性非小细胞肺癌患者的Capmatinib联合Trametinib的多中心I/Ib期研究

Lara, Matthew S; Riess, Jonathan W; Goldman, Jonathan W; Jiang, Fei; Bivona, Trever G; Blakely, Collin M

Phase 1 Study of Ceritinib Combined With Trametinib in Patients With Advanced ALK- or ROS1-Positive NSCLC

一项针对晚期ALK或ROS1阳性非小细胞肺癌患者的塞瑞替尼联合曲美替尼的I期研究

Lara, Matthew S; Gubens, Matthew A; Bacaltos, Bianca; Daran, Lea; Lim, Steffany L; Li, Tianhong; Gandara, David R; Bivona, Trever G; Riess, Jonathan W; Blakely, Collin M

Identifying historical and future potential lake drainage events on the western Arctic coastal plain of Alaska

确定阿拉斯加西部北极沿海平原的历史和未来潜在湖泊排水事件

Benjamin M Jones, Christopher D Arp, Guido Grosse, Ingmar Nitze, Mark J Lara, Matthew S Whitman, Louise M Farquharson, Mikhail Kanevskiy, Andrew D Parsekian, Amy L Breen, Nori Ohara, Rodrigo Correa Rangel, Kenneth M Hinkel2