日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

iPepGen: a modular, immunopeptidogenomic analysis pipeline for discovery, verification, and prioritization of cancer peptide neoantigen candidates

iPepGen:一种模块化的免疫肽基因组学分析流程,用于发现、验证和优先筛选癌症肽新抗原候选物。

Mehta, Subina; Wagner, Reid; Do, Katherine T; Johnson, James E; Yu, Fengchao; Jubenville, Tyler; Richards, Kyle; Coleman, Suzanne; Popescu, Flavia E; Nesvizhskii, Alexey I; Largaespada, David A; Jagtap, Pratik D; Griffin, Timothy J

Pharmacogenomic Synthetic Lethal Screens Reveal Hidden Vulnerabilities and New Therapeutic Approaches for Treatment of NF1-Associated Tumors

药物基因组学合成致死筛选揭示NF1相关肿瘤的潜在弱点和新的治疗方法

Williams, Kyle B; Larsson, Alex T; Keller, Bryant J; Chaney, Katherine E; Williams, Rory L; Bhunia, Minu M; Draper, Garrett M; Jubenville, Tyler A; Hudson, Wendy A; Georg, Gunda I; Moertel, Christopher L; Ratner, Nancy; Largaespada, David A

Non-viral TcBuster transposon engineering of CD70-CAR natural killer cells for the treatment of osteosarcoma.

利用非病毒 TcBuster 转座子工程改造 CD70-CAR 自然杀伤细胞,用于治疗骨肉瘤。

Robbins Gabrielle M, Chang Jae-Woong, Krueger Joshua B, Vue Young Y, Gilkey Alexandria K, Folsom Timothy D, Jubenville Tyler, Skeate Joseph G, Langworthy Benjamin W, Fitzgerald Katelyn M, Peterson Joseph J, Stelljes Erin M, Largaespada David A, Rahrmann Eric P, Webber Beau R, Moriarity Branden S

Direct interaction between human DDX1 and SARS-CoV-2 nucleocapsid protein is regulated by phosphorylation

人源DDX1与SARS-CoV-2核衣壳蛋白之间的直接相互作用受磷酸化调控

Wang, Liangjun; Baxley, Ryan M; Largaespada, David A; Aihara, Hideki; Bielinsky, Anja Katrin

The Cell Surface Proteome of Malignant Peripheral Nerve Sheath Tumors Reveals Therapeutic Targets

恶性周围神经鞘瘤细胞表面蛋白质组揭示治疗靶点

Stehn, Christopher M; Wang, Liangjun; Seeman, Zach; Largaespada, David A

Functional genomics for improving adoptive T-cell transfer therapies

利用功能基因组学改进过继性T细胞转移疗法

Skeate, Joseph G; Lee, Chang-Jung; Stewart, Carli; Fischbach, Mathew J; Kar, Bibekananda; Tsai, Alexander K; Kenderian, Saad S; Stromnes, Ingunn M; Largaespada, David A; Moriarity, Branden S; Rogers, Laura M

Author Correction: CREB5 promotes tumorigenicity and upregulates druggable cell surface modalities in basal-like breast cancer

作者更正:CREB5促进基底样乳腺癌的肿瘤发生并上调可药物靶向的细胞表面模式

Makovec, Allison; Boytim, Ella; Gustafson, Ava; Ludwig, Megan; Wang, Liangjun; Ali, Atef; Ishani, Khalid; Luo, Christine; Bergom, Hannah E; John, Emily; Tape, Sydney; Kellen, Samuel; Deacon, Aiden; Dewji, Fatemah Iman; Richter, Camden; Cookle, Lauren; Moline, David; Rennhack, Jonathan P; Drake, Justin M; Antonarakis, Emmanuel S; Largaespada, David A; Ostrander, Julie H; Hwang, Justin

CREB5 promotes tumorigenicity and upregulates druggable cell surface modalities in basal-like breast cancer

CREB5促进基底样乳腺癌的肿瘤发生并上调可药物靶向的细胞表面模式

Makovec, Allison; Boytim, Ella; Gustafson, Ava; Ludwig, Megan; Wang, Liangjun; Ali, Atef; Ishani, Khalid; Luo, Christine; Bergom, Hannah E; John, Emily; Tape, Sydney; Kellen, Samuel; Deacon, Aiden; Dewji, Fatemah Iman; Richter, Camden; Cookle, Lauren; Moline, David; Rennhack, Jonathan P; Drake, Justin M; Antonarakis, Emmanuel S; Largaespada, David A; Ostrander, Julie H; Hwang, Justin

Cell Type Specific Suppression of Hyper-Recombination by Human RAD18 Is Linked to Proliferating Cell Nuclear Antigen K164 Ubiquitination

人类 RAD18 对细胞类型特异性的超重组抑制与增殖细胞核抗原 K164 泛素化相关

Colette B Rogers, Wendy Leung, Ryan M Baxley, Rachel E Kram, Liangjun Wang, Joseph P Buytendorp, Khoi Le, David A Largaespada, Eric A Hendrickson, Anja-Katrin Bielinsky

DEAPR: Differential Expression and Pathway Ranking Tool Demonstrates NRAS(G12V) and NRAS(G12D) Mutations Have Differing Effects in THP-1 Cells

DEAPR:差异表达和通路排序工具表明 NRAS(G12V) 和 NRAS(G12D) 突变在 THP-1 细胞中具有不同的影响

Rathe, Susan K; White, Jeremy P; Sachs, Zohar; Largaespada, David A