The Ashkenazi-Centric G334R Variant of TP53 is Severely Impaired for Transactivation but Retains Tumor Suppressor Function in a Mouse Model.

TP53 的 Ashkenazi 中心 G334R 变体在转录激活方面严重受损，但在小鼠模型中仍保留肿瘤抑制功能