日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Cytokine profiling of molecular endotypes of knee osteoarthritis: insights from the IMI-APPROACH cohort

膝骨关节炎分子内型细胞因子谱分析：来自 IMI-APPROACH 队列研究的启示

期刊:Arthritis Research & Therapy
影响因子:4.6
doi:10.1186/s13075-026-03742-9
Hannani, Monica T; Bacardit, Jaume; Larkin, Jonathan; Glumoff, Virpi; Karsdal, Morten A; Bay-Jensen, Anne-Christine; Mobasheri, Ali; Thudium, Christian S
APP
关节炎
免疫/内分泌
细胞生物学
发表日期：2026
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Cleavage of Cartilage Oligomeric Matrix Protein (COMP) by ADAMTS4 generates a neoepitope associated with osteoarthritis and other forms of degenerative joint disease.

ADAMTS4 对软骨寡聚基质蛋白 (COMP) 的切割产生了一种与骨关节炎和其他形式的退行性关节疾病相关的新表位

期刊:Matrix Biology
影响因子:4.8
doi:10.1016/j.matbio.2024.12.005
de Groot Rens, Folgado Patricia Badía, Yamamoto Kazuhiro, Martin Daniel R, Koch Christopher D, Debruin Danielle, Blagg Sophie, Minns Alexander F, Bhutada Sumit, Ahnström Josefin, Larkin Jonathan, Aspberg Anders, Önnerfjord Patrik, Apte Suneel S, Santamaria Salvatore
炎症/感染
关节炎
炎症
发表日期：2025
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Rapidly progressive osteoarthritis (RPOA) in companion animals treated with bedinvetmab (Librela™): an expected pathophysiological phenomenon or a cause for concern?

使用贝地维单抗（Librela™）治疗的伴侣动物出现快速进展性骨关节炎（RPOA）：是预期的病理生理现象还是令人担忧的原因？

期刊:Frontiers in Veterinary Science
影响因子:2.9
doi:10.3389/fvets.2025.1640217
Mobasheri, Ali; Hanson, Peter; Larkin, Jonathan
关节炎
发表日期：2025
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Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development.

在特定时间窗口内，通过基因和药理学手段联合灭活紧密连接的 ADAMTS 蛋白酶，揭示了 versican 蛋白水解和 glypican-6 在心脏发育中的不同作用

期刊:Matrix Biology
影响因子:4.8
doi:10.1016/j.matbio.2024.05.003
Mead Timothy J, Bhutada Sumit, Foulcer Simon J, Peruzzi Niccolò, Nelson Courtney M, Seifert Deborah E, Larkin Jonathan, Tran-Lundmark Karin, Filmus Jorge, Apte Suneel S
发育与干细胞
发表日期：2024
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Development and validation of a machine learning-supported strategy of patient selection for osteoarthritis clinical trials: the IMI-APPROACH study

开发和验证一种基于机器学习的骨关节炎临床试验患者选择策略：IMI-APPROACH 研究

期刊:Osteoarthritis and Cartilage Open
影响因子:2.8
doi:10.1016/j.ocarto.2023.100406
Widera, Paweł; Welsing, Paco M J; Danso, Samuel O; Peelen, Sjaak; Kloppenburg, Margreet; Loef, Marieke; Marijnissen, Anne C; van Helvoort, Eefje M; Blanco, Francisco J; Magalhães, Joana; Berenbaum, Francis; Haugen, Ida K; Bay-Jensen, Anne-Christine; Mobasheri, Ali; Ladel, Christoph; Loughlin, John; Lafeber, Floris P J G; Lalande, Agnès; Larkin, Jonathan; Weinans, Harrie; Bacardit, Jaume
APP
关节炎
发表日期：2023
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Predicted and actual 2-year structural and pain progression in the IMI-APPROACH knee osteoarthritis cohort

IMI-APPROACH膝骨关节炎队列中预测和实际的2年结构和疼痛进展

期刊:Rheumatology
影响因子:4.4
doi:10.1093/rheumatology/keac292
van Helvoort, Eefje M; Jansen, Mylène P; Marijnissen, Anne C A; Kloppenburg, Margreet; Blanco, Francisco J; Haugen, Ida K; Berenbaum, Francis; Bay-Jensen, Anne-Christine C; Ladel, Christoph; Lalande, Agnes; Larkin, Jonathan; Loughlin, John; Mobasheri, Ali; Weinans, Harrie H; Widera, Pawel; Bacardit, Jaume; Welsing, Paco M J; Lafeber, Floris P J G
APP
关节炎
发表日期：2022
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Neuropathic pain in the IMI-APPROACH knee osteoarthritis cohort: prevalence and phenotyping

IMI-APPROACH膝骨关节炎队列中的神经性疼痛：患病率和表型

期刊:RMD Open
影响因子:4.7
doi:10.1136/rmdopen-2021-002025
van Helvoort, Eefje Martine; Welsing, Paco M J; Jansen, Mylène P; Gielis, Willem Paul; Loef, Marieke; Kloppenburg, Margreet; Blanco, Francisco; Haugen, Ida K; Berenbaum, Francis; Bay-Jensen, Anne-C; Ladel, Christoph; Lalande, Agnes; Larkin, Jonathan; Loughlin, John; Mobasheri, Ali; Weinans, Harrie; Lafeber, Floris; Eijkelkamp, Niels; Mastbergen, Simon
APP
关节炎
发表日期：2021
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Cohort profile: The Applied Public-Private Research enabling OsteoArthritis Clinical Headway (IMI-APPROACH) study: a 2-year, European, cohort study to describe, validate and predict phenotypes of osteoarthritis using clinical, imaging and biochemical markers

研究队列简介：应用公私合作研究促进骨关节炎临床进展（IMI-APPROACH）研究：一项为期2年的欧洲队列研究，旨在利用临床、影像学和生化标志物描述、验证和预测骨关节炎的表型。

期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2019-035101
van Helvoort, Eefje M; van Spil, Willem E; Jansen, Mylène P; Welsing, Paco M J; Kloppenburg, Margreet; Loef, Marieke; Blanco, Francisco J; Haugen, Ida K; Berenbaum, Francis; Bacardit, Jaume; Ladel, Christoph H; Loughlin, John; Bay-Jensen, Anne C; Mobasheri, Ali; Larkin, Jonathan; Boere, Janneke; Weinans, Harrie H; Lalande, Agnes; Marijnissen, Anne C A; Lafeber, Floris P J G
APP
关节炎
发表日期：2020
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Determinants of versican-V1 proteoglycan processing by the metalloproteinase ADAMTS5

金属蛋白酶ADAMTS5对versican-V1蛋白聚糖加工的决定因素

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M114.573287
Foulcer, Simon J; Nelson, Courtney M; Quintero, Maritza V; Kuberan, Balagurunathan; Larkin, Jonathan; Dours-Zimmermann, Maria T; Zimmermann, Dieter R; Apte, Suneel S
ADA
发表日期：2014
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