Higher order receptor clustering due to the IgG3 subclass is necessary for TLR4 signaling and tolerance induction by novel human anti-TLR4 antibodies.
由于 IgG3 亚类引起的高阶受体聚集对于 TLR4 信号传导和新型人类抗 TLR4 抗体诱导耐受性是必要的
期刊:MAbs
影响因子:7.3
doi:10.1080/19420862.2025.2515415
Heuer Luke S, Sweeney Nicolle, Rojas Manuel, Zhang Weici, Mendelsohn Andrew R, Huang Manley, Yu Bo, Ackerman Paulina, Wei Qisheng, Herr Andrew B, Larrick James W, Ridgway William M