日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Attenuating mitochondrial dysfunction and morphological disruption with PT320 delays dopamine degeneration in MitoPark mice

使用 PT320 减轻线粒体功能障碍和形态破坏可延缓 MitoPark 小鼠的多巴胺退化

Vicki Wang, Kuan-Yin Tseng, Tung-Tai Kuo, Eagle Yi-Kung Huang, Kuo-Lun Lan, Zi-Rong Chen, Kuo-Hsing Ma, Nigel H Greig, Jin Jung, Ho-Ii Choi, Lars Olson, Barry J Hoffer, Yuan-Hao Chen

Serotonergic Regulation of Synaptic Dopamine Levels Mitigates L-DOPA-Induced Dyskinesia in a Mouse Model of Parkinson's Disease

血清素调节突触多巴胺水平可减轻帕金森病小鼠模型中左旋多巴诱发的运动障碍

Yuan-Hao Chen, Tung-Tai Kuo, Vicki Wang, Pin-Wen Cheng, Eagle Yi-Kung Huang, Kuo-Hsing Ma, Nigel H Greig, Lars Olson, Barry J Hoffer, Kuan-Yin Tseng

Mitochondrial Dysfunction and Protein Homeostasis in Aging: Insights from a Premature-Aging Mouse Model

衰老过程中的线粒体功能障碍和蛋白质稳态:来自过早衰老小鼠模型的见解

Jaime M Ross, Lars Olson, Giuseppe Coppotelli

Microglial Nogo delays recovery following traumatic brain injury in mice

小胶质细胞 Nogo 延迟小鼠脑外伤后的恢复

Elliot J Glotfelty, Shih-Chang Hsueh, Quia Claybourne, Alicia Bedolla, Katherine O Kopp, Tonya Wallace, Binhai Zheng, Yu Luo, Tobias E Karlsson, Ross A McDevitt, Lars Olson, Nigel H Greig

The RhoA-ROCK1/ROCK2 Pathway Exacerbates Inflammatory Signaling in Immortalized and Primary Microglia

RhoA-ROCK1/ROCK2通路加剧永生化和原代小胶质细胞中的炎症信号传导

Elliot J Glotfelty ,Luis B Tovar-Y-Romo ,Shih-Chang Hsueh ,David Tweedie ,Yazhou Li ,Brandon K Harvey ,Barry J Hoffer ,Tobias E Karlsson ,Lars Olson ,Nigel H Greig

Sustained Release GLP-1 Agonist PT320 Delays Disease Progression in a Mouse Model of Parkinson's Disease

缓释型 GLP-1 激动剂 PT320 可延缓帕金森病小鼠模型的病情进展

Vicki Wang, Tung-Tai Kuo, Eagle Yi-Kung Huang, Kuo-Hsing Ma, Yu-Ching Chou, Zhao-Yang Fu, Li-Wen Lai, Jin Jung, Hoi-Ii Choi, Doo-Sup Choi, Yazhou Li, Lars Olson, Nigel H Greig, Barry J Hoffer, Yuan-Hao Chen

Mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response

成人中脑多巴胺神经元的线粒体功能障碍引发早期免疫反应

Roberta Filograna, Seungmin Lee, Katarína Tiklová, Mara Mennuni, Viktor Jonsson, Markus Ringnér, Linda Gillberg, Elena Sopova, Oleg Shupliakov, Camilla Koolmeister, Lars Olson, Thomas Perlmann, Nils-Göran Larsson

Forebrain NgR1 Overexpression Impairs DA Release Suggesting Synergy of Local and Global Synaptic Plasticity Mechanisms

前脑 NgR1 过度表达损害 DA 释放,表明局部和整体突触可塑性机制具有协同作用

Emma Arvidsson, Sarolta Gabulya, Alvin Tore Brodin, Tobias Erik Karlsson, Lars Olson

Voluntary exercise normalizes the proteomic landscape in muscle and brain and improves the phenotype of progeroid mice

自愿锻炼使肌肉和大脑的蛋白质组学景观正常化并改善早衰小鼠的表型

Jaime M Ross, Giuseppe Coppotelli, Rui M Branca, Kyung M Kim, Janne Lehtiö, David A Sinclair, Lars Olson

Off-Target Effects in Transgenic Mice: Characterization of Dopamine Transporter (DAT)-Cre Transgenic Mouse Lines Exposes Multiple Non-Dopaminergic Neuronal Clusters Available for Selective Targeting within Limbic Neurocircuitry

转基因小鼠的脱靶效应:多巴胺转运蛋白 (DAT)-Cre 转基因小鼠系的表征揭示了边缘神经回路中可用于选择性靶向的多个非多巴胺能神经元簇

Maria Papathanou, Sylvie Dumas, Hanna Pettersson, Lars Olson, Åsa Wallén-Mackenzie