日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88

抗菌肽 Api137 和 Api88 对细菌核糖体的多模式结合和抑制

Simon M Lauer #, Maren Reepmeyer #, Ole Berendes, Dorota Klepacki, Jakob Gasse, Sara Gabrielli, Helmut Grubmüller, Lars V Bock, Andor Krizsan, Rainer Nikolay, Christian M T Spahn, Ralf Hoffmann1

The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome

SecM 阻滞肽捕获核糖体的前肽键形成状态

Felix Gersteuer #, Martino Morici #, Sara Gabrielli, Keigo Fujiwara, Haaris A Safdari, Helge Paternoga, Lars V Bock, Shinobu Chiba, Daniel N Wilson

Structural conservation of antibiotic interaction with ribosomes

抗生素与核糖体相互作用的结构保守性

Helge Paternoga #, Caillan Crowe-McAuliffe #, Lars V Bock, Timm O Koller, Martino Morici, Bertrand Beckert, Alexander G Myasnikov, Helmut Grubmüller, Jiří Nováček, Daniel N Wilson

Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics

大环内酯类和酮内酯类抗生素抑制翻译的结构和机制基础

Bertrand Beckert #, Elodie C Leroy #, Shanmugapriya Sothiselvam #, Lars V Bock #, Maxim S Svetlov, Michael Graf, Stefan Arenz, Maha Abdelshahid, Britta Seip, Helmut Grubmüller, Alexander S Mankin, C Axel Innis, Nora Vázquez-Laslop, Daniel N Wilson

A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest

低温电子显微镜和分子动力学相结合的方法揭示了 ErmBL 介导的翻译停滞机制

Stefan Arenz, Lars V Bock, Michael Graf, C Axel Innis, Roland Beckmann, Helmut Grubmüller, Andrea C Vaiana, Daniel N Wilson