日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Amyotrophic lateral sclerosis caused by TARDBP mutations: from genetics to TDP-43 proteinopathy

由TARDBP基因突变引起的肌萎缩侧索硬化症:从遗传学到TDP-43蛋白病

Balendra, Rubika; Sreedharan, Jemeen; Hallegger, Martina; Luisier, Raphaëlle; Lashuel, Hilal A; Gregory, Jenna M; Patani, Rickie

Self-driving microscopy detects the onset of protein aggregation and enables intelligent Brillouin imaging

自主显微镜能够检测蛋白质聚集的发生,并实现智能布里渊成像。

Ibrahim, Khalid A; Cathala, Camille; Bevilacqua, Carlo; Feletti, Lely; Prevedel, Robert; Lashuel, Hilal A; Radenovic, Aleksandra

Nanoplasmonic Infrared Microarray Sensor Enabling Structural Protein Biomarker-Based Drug Screening for Neurodegenerative Diseases

纳米等离子体红外微阵列传感器助力基于结构蛋白生物标志物的神经退行性疾病药物筛选

Kavungal, Deepthy; Morro, Enzo; Kumar, Senthil T; Dagli, Berkay; Lashuel, Hilal A; Altug, Hatice

Alpha-synuclein seed amplification assays: Data sharing, standardization needed for clinical use

α-突触核蛋白种子扩增检测:临床应用需要数据共享和标准化。

Lashuel, Hilal A; Surmeier, D James; Simuni, Tanya; Merchant, Kalpana; Caughey, Byron; Soto, Claudio; Fares, Mohamed-Bilal; Heym, Roland G; Melki, Ronald

Differential role of C-terminal truncations on alpha-synuclein pathology and Lewy body formation.

端截短对 α-突触核蛋白病理和路易体形成的影响差异

Mahul-Mellier Anne-Laure, Altay Melek Firat, Maharjan Niran, Ait-Bouziad Nadine, Chiki Anass, Jagannath Somanath, Limorenko Galina, Novello Salvatore, Ricci Jonathan, Jasiqi Yllza, Vingill Siv, Wade-Martins Richard, Holton Janice, Strand Catherine, Haikal Caroline, Li Jia-Yi, Hamelin Romain, Croisier Marie, Knott Graham, Mairet-Coello Georges, Weerens Laura, Michel Anne, Downey Patrick, Citron Martin, Lashuel Hilal A

Huntingtin inclusion bodies have distinct immunophenotypes and ubiquitination profiles in the Huntington's disease human cerebral cortex.

亨廷顿病患者大脑皮层中的亨廷顿蛋白包涵体具有独特的免疫表型和泛素化特征

Swanson Molly E V, Tan Adelie Y S, Tippett Lynette J, Turner Clinton P, Curtis Maurice A, Scotter Emma L, Lashuel Hilal A, Dragunow Mike, Faull Richard L M, Murray Helen C, Singh-Bains Malvindar K

Defined human tri-lineage brain microtissues.

已定义的人类三系脑微组织

Uenaka Takeshi, Jung Sascha, Kumar Ishan, Vodehnal Kit, Rastogi Mohit, Yoo Yongjin, Koontz Mark, Thome Christian, Li Wanhua, Chan Tamara, Green Erin M, Chesnov Kirill, Sun Zijun, Zhang Shuyuan, Wang Jinzhao, Venida Anthony, Mellier Anne-Laure Mahul, Atkins Micaiah, Jackrel Meredith, Skotheim Jan M, Wyss-Coray Tony, Abu-Remaileh Monther, Lashuel Hilal A, Bassik Michael C, Südhof Thomas C, Del Sol Antonio, Ullian Erik, Wernig Marius

Deep Learning-Assisted Single-Molecule Detection of Protein Post-translational Modifications with a Biological Nanopore

利用深度学习辅助生物纳米孔进行蛋白质翻译后修饰的单分子检测

Cao, Chan; Magalhães, Pedro; Krapp, Lucien F; Bada Juarez, Juan F; Mayer, Simon Finn; Rukes, Verena; Chiki, Anass; Lashuel, Hilal A; Dal Peraro, Matteo

Author Correction: Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates

作者更正:完全不含辅因子的ClearTau平台可产生具有成核能力的Tau原纤维,用于重建病理性Tau聚集体。

Limorenko, Galina; Tatli, Meltem; Kolla, Rajasekhar; Nazarov, Sergey; Weil, Marie-Theres; Schöndorf, David C; Geist, Daniela; Reinhardt, Peter; Ehrnhoefer, Dagmar E; Stahlberg, Henning; Gasparini, Laura; Lashuel, Hilal A

A Versatile Method for Site-Specific Chemical Installation of Aromatic Posttranslational Modification Analogs into Proteins

一种将芳香族翻译后修饰类似物定点化学引入蛋白质的通用方法

Lin, Xiaoxi; Mandal, Shaswati; Nithun, Raj V; Kolla, Rajasekhar; Bouri, Bouchra; Lashuel, Hilal A; Jbara, Muhammad