日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Leveraging single cell multiomic analyses to identify gene regulatory networks that drive human articular cartilage cell fate

利用单细胞多组学分析来识别驱动人类关节软骨细胞命运的基因调控网络

Jachim, Sarah K; Venkatasubramanian, Divya; Senevirathne, Gayani; Zhu, Andrew S; Vitale, Concetta S; Melendez, Delmy L; Zhang, Cheng-Hai; Lassar, Andrew B; Capellini, Terence D; Craft, April M

Genetic interaction between Adgrg6 and Sox9 reveals a feedforward mechanism for postnatal spinal stability

Adgrg6 和 Sox9 之间的基因相互作用揭示了一种促进出生后脊柱稳定性的前馈机制

Aceves, Valeria; Xu, Ziyi; Zhang, Cheng-Hai; Kim, Jongkil; Ito, Joshua; Mathers, Kylie; Lassar, Andrew; Liu, Zhaoyang; Gray, Ryan

Genetic interaction between Adgrg6 and Sox9 reveals a feedforward mechanism for postnatal spinal stability

Adgrg6 和 Sox9 之间的基因相互作用揭示了一种促进出生后脊柱稳定性的前馈机制

Gray, Ryan; Aceves, Valeria; Xu, Ziyi; Zhang, Cheng-Hai; Kim, Jongkil; Ito, Joshua; Mathers, Kylie; Lassar, Andrew; Liu, Zhaoyang

Creb5 controls its own expression and directly induces the joint interzone regulatory program

Creb5 控制自身表达并直接诱导联合区间调控程序

Zhang, Cheng-Hai; Shahini, Aref; Cook, Laura E; Mistry, Meeta; Kim, Jongkil; Wick, Heather; Pennacchio, Len A; Lassar, Andrew B

FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton

FOXC1 和 FOXC2 调节小鼠胚胎肢体骨骼中生长板软骨细胞的成熟和肥大

Asra Almubarak, Qiuwan Zhang, Cheng-Hai Zhang, Noor Abdelwahab, Tsutomu Kume, Andrew B Lassar, Fred B Berry

Foxc1 and Foxc2 function in osteochondral progenitors for the progression through chondrocyte hypertrophy and mineralization of the primary ossification center

Foxc1 和 Foxc2 在骨软骨祖细胞中发挥作用,促进软骨细胞肥大和初级骨化中心矿化

Asra Almubarak, Qiuwan Zhang, Cheng-Hai Zhang, Andrew B Lassar, Tsutomu Kume, Fred B Berry

Creb5 coordinates synovial joint formation with the genesis of articular cartilage

Creb5 协调滑膜关节形成与关节软骨的发生

Cheng-Hai Zhang, Yao Gao, Han-Hwa Hung, Zhu Zhuo, Alan J Grodzinsky, Andrew B Lassar

Overexpression of transcription factor FoxA2 in the developing skeleton causes an enlargement of the cartilage hypertrophic zone, but it does not trigger ectopic differentiation in immature chondrocytes

发育中的骨骼中转录因子FoxA2的过度表达会导致软骨肥大区扩大,但不会引发未成熟软骨细胞的异位分化。

Nicole Bell ,Sanket Bhagat ,Shanmugam Muruganandan ,Ryunhyung Kim ,Kailing Ho ,Rachel Pierce ,Elena Kozhemyakina ,Andrew B Lassar ,Laura Gamer ,Vicki Rosen ,Andreia M Ionescu

Colchicine protects against cartilage degeneration by inhibiting MMP13 expression via PLC-γ1 phosphorylation

秋水仙碱通过 PLC-γ1 磷酸化抑制 MMP13 表达,防止软骨退化

K Takeuchi, H Ogawa, N Kuramitsu, K Akaike, A Goto, H Aoki, A Lassar, Y Suehara, A Hara, K Matsumoto, H Akiyama

Creb5 establishes the competence for Prg4 expression in articular cartilage

Creb5 确立了 Prg4 在关节软骨中的表达能力

Cheng-Hai Zhang, Yao Gao, Unmesh Jadhav, Han-Hwa Hung, Kristina M Holton, Alan J Grodzinsky, Ramesh A Shivdasani, Andrew B Lassar