文献库，生知库 | 链接生命科学的每一步

Characterization of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein

对一种在刺突蛋白S1/S2连接处发生缺失的减毒SARS-CoV-2变异株进行表征

Wang, Pui; Lau, Siu-Ying; Deng, Shaofeng; Chen, Pin; Mok, Bobo Wing-Yee; Zhang, Anna Jinxia; Lee, Andrew Chak-Yiu; Chan, Kwok-Hung; Tam, Rachel Chun-Yee; Xu, Haoran; Zhou, Runhong; Song, Wenjun; Liu, Li; To, Kelvin Kai-Wang; Chan, Jasper Fuk-Woo; Chen, Zhiwei; Yuen, Kwok-Yung; Chen, Honglin

SARS-CoV-2

发表日期：2021

文献求助收藏

Natural Transmission of Bat-like Severe Acute Respiratory Syndrome Coronavirus 2 Without Proline-Arginine-Arginine-Alanine Variants in Coronavirus Disease 2019 Patients

2019冠状病毒病患者中无脯氨酸-精氨酸-精氨酸-丙氨酸变异体的蝙蝠样严重急性呼吸综合征冠状病毒2的自然传播

期刊:Clinical Infectious Diseases

影响因子:7.3

doi:10.1093/cid/ciaa953

Wong, Yik Chun; Lau, Siu Ying; Wang To, Kelvin Kai; Mok, Bobo Wing Yee; Li, Xin; Wang, Pui; Deng, Shaofeng; Woo, Kin Fai; Du, Zhenglong; Li, Cun; Zhou, Jie; Chan, Jasper Fuk Woo; Yuen, Kwok Yung; Chen, Honglin; Chen, Zhiwei

微生物学

发表日期：2021

文献求助收藏

Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters

严重急性呼吸综合征冠状病毒2和甲型H1N1流感病毒（H1N1）pdm09的合并感染会加重金丝鼠肺炎的病情。

期刊:Clinical Infectious Diseases

影响因子:7.3

doi:10.1093/cid/ciaa1747

Zhang, Anna Jinxia; Lee, Andrew Chak-Yiu; Chan, Jasper Fuk-Woo; Liu, Feifei; Li, Can; Chen, Yanxia; Chu, Hin; Lau, Siu-Ying; Wang, Pui; Chan, Chris Chung-Sing; Poon, Vincent Kwok-Man; Yuan, Shuofeng; To, Kelvin Kai-Wang; Chen, Honglin; Yuen, Kwok-Yung

Intradermal vaccination of live attenuated influenza vaccine protects mice against homologous and heterologous influenza challenges

皮内注射减毒活流感疫苗可保护小鼠免受同源和异源流感病毒的攻击。

期刊:NPJ Vaccines

影响因子:6.5

doi:10.1038/s41541-021-00359-8

Lee, Andrew Chak-Yiu; Zhang, Anna Jinxia; Li, Can; Chen, Yanxia; Liu, Feifei; Zhao, Yan; Chu, Hin; Fong, Carol Ho-Yan; Wang, Pui; Lau, Siu-Ying; To, Kelvin Kai-Wang; Chen, Honglin; Yuen, Kwok-Yung

Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters

低剂量SARS-CoV-2 Alpha变种病毒接种物在仓鼠体内的传播效率比早期变种病毒更高。

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-021-02640-x

Mok, Bobo Wing-Yee; Liu, Honglian; Deng, Shaofeng; Liu, Jiayan; Zhang, Anna Jinxia; Lau, Siu-Ying; Liu, Siwen; Tam, Rachel Chun-Yee; Cremin, Conor J; Ng, Timothy Ting-Leung; Leung, Jake Siu-Lun; Lee, Lam-Kwong; Wang, Pui; To, Kelvin Kai-Wang; Chan, Jasper Fuk-Woo; Chan, Kwok-Hung; Yuen, Kwok-Yung; Siu, Gilman Kit-Hang; Chen, Honglin

Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction

在S1/S2连接处发生缺失的减毒SARS-CoV-2变异株

期刊:Emerging Microbes & Infections

影响因子:7.5

doi:10.1080/22221751.2020.1756700

Lau, Siu-Ying; Wang, Pui; Mok, Bobo Wing-Yee; Zhang, Anna Jinxia; Chu, Hin; Lee, Andrew Chak-Yiu; Deng, Shaofeng; Chen, Pin; Chan, Kwok-Hung; Song, Wenjun; Chen, Zhiwei; To, Kelvin Kai-Wang; Chan, Jasper Fuk-Woo; Yuen, Kwok-Yung; Chen, Honglin

SARS-CoV-2

发表日期：2020

文献求助收藏

Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines

DelNS1流感病毒的制备：一种优化减毒活流感疫苗的策略

期刊:mBio

影响因子:4.7

doi:10.1128/mBio.02180-19

Wang, Pui; Zheng, Min; Lau, Siu-Ying; Chen, Pin; Mok, Bobo Wing-Yee; Liu, Siwen; Liu, Honglian; Huang, Xiaofeng; Cremin, Conor J; Song, Wenjun; Chen, Yixin; Wong, Yik-Chun; Huang, Haode; To, Kelvin Kai-Wong; Chen, Zhiwei; Xia, Ningshao; Yuen, Kwok-Yung; Chen, Honglin

The PB2 Polymerase Host Adaptation Substitutions Prime Avian Indonesia Sub Clade 2.1 H5N1 Viruses for Infecting Humans

PB2聚合酶宿主适应性替换使印尼亚分支2.1 H5N1病毒更容易感染人类

期刊:Viruses-Basel

影响因子:3.5

doi:10.3390/v11030292

Wang, Pui; Song, Wenjun; Mok, Bobo Wing-Yee; Zheng, Min; Lau, Siu-Ying; Liu, Siwen; Chen, Pin; Huang, Xiaofeng; Liu, Honglian; Cremin, Conor J; Chen, Honglin

Unique reassortant of influenza A(H7N9) virus associated with severe disease emerging in Hong Kong

与香港出现的严重疾病相关的甲型H7N9流感病毒独特重组株

期刊:Journal of Infection

影响因子:11.9

doi:10.1016/j.jinf.2014.02.012

To, Kelvin Kai-Wang; Song, Wenjun; Lau, Siu-Ying; Que, Tak-Lun; Lung, David Christopher; Hung, Ivan Fan-Ngai; Chen, Honglin; Yuen, Kwok-Yung

A statistical framework for quantifying the nuclear export rate of influenza viral mRNAs.

用于量化流感病毒mRNA核输出率的统计框架

Characterization of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein

对一种在刺突蛋白S1/S2连接处发生缺失的减毒SARS-CoV-2变异株进行表征

Natural Transmission of Bat-like Severe Acute Respiratory Syndrome Coronavirus 2 Without Proline-Arginine-Arginine-Alanine Variants in Coronavirus Disease 2019 Patients

2019冠状病毒病患者中无脯氨酸-精氨酸-精氨酸-丙氨酸变异体的蝙蝠样严重急性呼吸综合征冠状病毒2的自然传播

Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters

严重急性呼吸综合征冠状病毒2和甲型H1N1流感病毒（H1N1）pdm09的合并感染会加重金丝鼠肺炎的病情。

Intradermal vaccination of live attenuated influenza vaccine protects mice against homologous and heterologous influenza challenges

皮内注射减毒活流感疫苗可保护小鼠免受同源和异源流感病毒的攻击。

Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters

低剂量SARS-CoV-2 Alpha变种病毒接种物在仓鼠体内的传播效率比早期变种病毒更高。

Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction

在S1/S2连接处发生缺失的减毒SARS-CoV-2变异株

Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines

DelNS1流感病毒的制备：一种优化减毒活流感疫苗的策略

The PB2 Polymerase Host Adaptation Substitutions Prime Avian Indonesia Sub Clade 2.1 H5N1 Viruses for Infecting Humans

PB2聚合酶宿主适应性替换使印尼亚分支2.1 H5N1病毒更容易感染人类

Unique reassortant of influenza A(H7N9) virus associated with severe disease emerging in Hong Kong

与香港出现的严重疾病相关的甲型H7N9流感病毒独特重组株