日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Proof of Concept Application of Hydrophilic Interaction Chromatography for Direct Online Disruption of Lipid Nanoparticles, Intact mRNA Analysis, and Measure of Encapsulation Efficiency

亲水相互作用色谱法在脂质纳米颗粒直接在线破碎、完整mRNA分析和包封效率测定中的概念验证应用

Maurer, Jonathan; Lauber, Matthew A; Fekete, Szabolcs; Imiołek, Mateusz; Malburet, Camille; François-Heude, Marc; Guillarme, Davy

High-Efficiency Analytical Protein A Columns for High Sensitivity Monoclonal Antibody Titer Analysis

用于高灵敏度单克隆抗体滴度分析的高效分析型蛋白A柱

Muriithi, Beatrice; Gritti, Fabrice; Gilar, Martin; Sarisozen, Yeliz; Lauber, Matthew; Wyndham, Kevin

Coupling of Size Exclusion Chromatography to High Throughput Charge Detection Mass Spectrometry for the Analysis of Large Proteins and Virus-like Particles

将尺寸排阻色谱与高通量电荷检测质谱联用分析大分子蛋白质和病毒样颗粒

Parikh, Raj A; Miller, Lohra M; Draper, Benjamin E; Kizekai, Lavelay; Addepalli, Balasubrahmanyam; Chen, Michelle; Lauber, Matthew A; Jarrold, Martin F

High-Throughput Quantification and Characterization of Dual Payload mRNA/LNP Cargo via Deformulating Size Exclusion and Ion Pairing Reversed Phase Assays.

通过重构尺寸排阻和离子对反相分析对双有效载荷 mRNA/LNP 货物进行高通量定量和表征

Imiołek Mateusz, Cojocaru Razvan, Fekete Szabolcs, Le Huray Jon, Lauber Matthew

High-Throughput Chromatographic Separation of Oligonucleotides: A Proof of Concept Using Ultra-Short Columns

寡核苷酸的高通量色谱分离:使用超短柱的概念验证

Lardeux, Honorine; Fekete, Szabolcs; Lauber, Matthew; D'Atri, Valentina; Guillarme, Davy

Challenges and emerging trends in liquid chromatography-based analyses of mRNA pharmaceuticals

基于液相色谱法的mRNA药物分析面临的挑战和新兴趋势

Fekete, Szabolcs; Doneanu, Catalin; Addepalli, Balasubrahmayam; Gaye, Maissa; Nguyen, Jennifer; Alden, Bonnie; Birdsall, Robert; Han, Duanduan; Isaac, Giorgis; Lauber, Matthew

Pressure-Enhanced Liquid Chromatography, a Proof of Concept: Tuning Selectivity with Pressure Changes and Gradients

压力增强液相色谱法:概念验证:利用压力变化和梯度调节选择性

Fekete, Szabolcs; Fogwill, Michael; Lauber, Matthew A

Ultra-Fast Middle-Up Reversed Phase Liquid Chromatography Analysis of Complex Bispecific Antibodies Obtained in Less Than One Minute

不到一分钟即可获得复杂双特异性抗体的超快速中上反相液相色谱分析

Murisier, Amarande; D'Atri, Valentina; Pirner, Sebastian; Larraillet, Vincent; Fekete, Szabolcs; Lauber, Matthew; Guillarme, Davy

Expediting the chromatographic analysis of COVID-19 antibody therapeutics with ultra-short columns, retention modeling and automated method development

利用超短色谱柱、保留模型和自动化方法开发加速 COVID-19 抗体疗法的色谱分析

Duivelshof, Bastiaan; Zöldhegyi, Arnold; Guillarme, Davy; Lauber, Matthew; Fekete, Szabolcs

Direct coupling of size exclusion chromatography and mass spectrometry for the characterization of complex monoclonal antibody products

利用尺寸排阻色谱和质谱直接联用技术表征复杂的单克隆抗体产品

Murisier, Amarande; Andrie, Marie; Fekete, Szabolcs; Lauber, Matthew; D'Atri, Valentina; Iwan, Katharina; Guillarme, Davy